Biotech News Brief

Biotech news for Tuesday, May 5, 2026, ranked by our 5-dimension investment framework — regulatory, technology, commercial, manufacturing, and narrative.

May 5, 6:26 AM EDT

Strong Buy at under $10: The highest Quant-rated bargain stocks right now

GTEALTO

Jonathan Kitchen Seeking Alpha's Quant Rating system has identified a group of sub-$10 stocks that score near the very top of its quantitative rankings, a rare distinction given that penny and micro-cap stocks often struggle to meet the profitability, growth,…

May 5, 5:20 AM EDT

Biggest stock movers Tuesday: INTC, DUOL, and more

PLTRDUOLAAPL

design master Stock futures edged higher early Tuesday as investors tracked renewed Middle East tensions while eyeing key economic data later this week. Here are some of Tuesday's biggest stock movers: Biggest stock gainers Pinterest ( PINS ) +16% - Shares sur…

May 4, 11:04 PM EDT

Vertex projects 2026 revenue of $12.95B-$13.1B while targeting $500M-plus from non-CF products

VRTX

Earnings Call Insights: Vertex Pharmaceuticals (VRTX) Q1 2026 Management View "Vertex is off to a terrific start in 2026, which we see as a year defined by execution" (CEO, President & Director Reshma Kewalramani), citing "total product revenue of $2.99 bi…

May 4, 9:34 PM EDT

BioMarin outlines $3.825B-$3.925B 2026 revenue outlook driven by Amicus integration and 20% growth target

BMRN

Earnings Call Insights: BioMarin Pharmaceutical Inc. (BMRN) Q1 2026 Management View "I am so pleased that we completed the Amicus acquisition last week... with the addition of 2 innovative therapies, Galafold for Fabry disease and Pombiliti and Opfolda for Pom…

May 4, 4:27 PM EDT

Ocugen issues $115M notes to repay debt; stock faces after-hours selling

OCGN

Ocugen ( OCGN ) announced on Monday that it plans to raise about $115M through Convertible Senior Notes due 2034 in a private placement to qualified institutional buyers. Additionally, it also plans a 13-day option for the initial purchaser to raise an additio…

May 4, 2:42 PM EDT

Amgen to spend another $300M on US manufacturing

AMGN

Sundry Photography Amgen ( AMGN ) said it is boosting its already significant investment to add to its US manufacturing capacity through an additional $300M. The large biopharma is specifically expanding an existing biologic facility in Juncos, Puerto Rico. Si…

May 4, 1:54 PM EDT

Twist Bioscience targets $442M-$447M FY2026 revenue while staying on track for Q4 FY2026 adjusted EBITDA breakeven

TWST

Earnings Call Insights: Twist Bioscience (TWST) Q2 fiscal 2026 Management View “Twist delivered another strong quarter and extended our track record of consistent execution, posting our 13th quarter of sequential revenue growth,” said (CEO Emily Leproust), add…

May 4, 1:44 PM EDT

Krystal Biotech outlines $175M-$195M 2026 non-GAAP opex while targeting 6 data readouts before year-end

KRYS

Earnings Call Insights: Krystal Biotech (KRYS) Q1 2026 Management View "We delivered another quarter of global revenue growth with net revenue of $116.4 million in the Q." (Founder, Chairman, President & CEO Krish Krishnan) "Gross margin was 95%, and we de…

May 4, 10:24 AM EDT

ADC Therapeutics targets $600M-$1B U.S. peak ZYNLONTA revenue as LOTIS-5 top-line data is expected by end of June

ADCT

Earnings Call Insights: ADC Therapeutics (ADCT) Q1 2026 Management View "We continue to make good progress in the first quarter of 2026 as we advance towards multiple important milestones for ZYNLONTA over the remainder of the year, beginning with the expected

May 4, 9:50 AM EDT

Most and least shorted healthcare stocks with up to $2B market cap in May

XLVSNSEIBBPPH

iQoncept/iStock via Getty Images Short sellers aggressively ramped up their positions in small-cap healthcare stocks, driving a significant spike in bearish sentiment for companies with market capitalizations under $2 billion, according to April-end figures. I…

May 4, 9:35 AM EDT

Most and least shorted mid-to mega-cap healthcare stocks in May

XLVHIMSIBBPPH

iQoncept/iStock via Getty Images Short interest data from late April indicates varying investor feelings in the healthcare sector, with strong bearish bets on biotechnology and telehealth through May 2026. Telehealth and biotechnology are facing bearish sentim…

May 4, 9:10 AM EDT

Aura Biosciences prices $260M stock, warrant offering

AURA

Aura Biosciences ( NASDAQ: AURA ) on Monday said it has priced an underwritten public offering expected to raise about $260.3 million in gross proceeds. The offering includes 39.6 million shares of common stock priced at $6.00 per share and pre-funded warrants…

May 4, 8:50 AM EDT

MacroGenics expands ZYNYZ royalty deal with Sagard, secures $60M upfront

MGNX

MacroGenics ( NASDAQ: MGNX ) on Monday said it has entered into an expanded royalty purchase agreement with Sagard Healthcare Partners tied to global sales of its drug ZYNYZ. MacroGenics said it will receive $60 million upfront and could get up to $20 million

May 4, 8:34 AM EDT

Pasithea Therapeutics appoints chief medical officer

KTTAAMGNRCUS

Pasithea Therapeutics ( KTTA ) said on Monday it appointed Kartik Krishnan as chief medical officer as it advances its lead candidate, PAS-004, which is a next-generation MEK inhibitor. Krishnan will oversee clinical strategy and development, with a focus on n…

May 4, 7:03 AM EDT

Cabaletta Bio prices $150M stock offering

CABALLY

Cabaletta Bio ( CABA ) priced an underwritten offering of 51.7M shares at $2.90 each, raising about $150M in proceeds. The purchase price represents the at-the-market price under Nasdaq rules. The sale is expected to close on or about May 5, 2026, subject to

May 4, 6:17 AM EDT

Aura Biosciences names Natalie Holles as CEO

AURA

Aura Biosciences ( AURA ) Monday said that Natalie Holles has been appointed CEO and President, effective April 30. Holles succeeds founder Elisabet de los Pinos, who stepped down from the roles the same date. The company also announced it has enrolled 86 pati…

May 3, 11:15 AM EDT

Key deals this week: Organon, ARC Resources, Nebius, Eli Lilly and more

ESPRNBIS

fengdr Here's a list of key deals reported across sectors this week: Esperion Therapeutics ( ESPR ) shares jumped about 57% in premarket trading on Friday after the drugmaker agreed to be acquired by healthcare investment firm ARCHIMED in a deal

May 3, 9:30 AM EDT

Quant snapshot: Lumentum, Fastly among top-rated names as SUI Group, Service Properties lag

PLTRAMD

Quant rankings for the upcoming earnings calendar show strength concentrated across information technology, energy, and materials, while weakness is more pronounced in health care, consumer-facing segments, and real estate. A total of 1468 companies are schedu…

May 1, 5:52 PM EDT

Moderna expects up to 10% 2026 revenue growth and $4.5B-$5B year-end cash, while targeting ~$4.2B cash costs

MRNA

Earnings Call Insights: Moderna (MRNA) Q1 2026 Management view Moderna described Q1 performance as driven by international execution, with CEO Stéphane Bancel saying, "In the first quarter, we grew year-over-year revenues significantly to $0.4 billion, driven…

May 1, 5:42 PM EDT

Vanda rises after hours on launch of tradipitant for motion sickness

VNDA

Koldunova_Anna/iStock via Getty Images Vanda Pharmaceuticals ( VNDA ) is up ~3% in after-hours trading Friday after announcing the availability of Nereus (tradipitant) for the prevention of vomiting induced by motion in adults. The company said that Nereus is…