Jun 3, 12:53 PM EDT
TG Therapeutics rises on early-stage trial data for Briumvi injectable
TGTX
Md Saiful Islam Khan/iStock via Getty Images TG Therapeutics ( TGTX ) added more than 10% on Wednesday after data from an early-stage trial evaluating a subcutaneously delivered version of its top-selling drug, Briumvi, supported a quarterly dosing regimen cur…
Jun 3, 12:29 PM EDT
Protean Funds makes portfolio changes with additions and exits
OCTVTRUBF
Protean Small Cap gained 5.7% in May, outperforming the Carnegie Nordic Small-Cap Index's 3.3% return. Meanwhile, Protean Select returned 1.4% in May, while Protean Aktiesparfond Norden gained 3.2%, trailing its benchmark index's 4.0% rise. The fund initiated…
Jun 3, 11:30 AM EDT
Rezolute upgraded at Citizens after late-stage trial data for lead asset
RZLT
alexsl Rezolute ( RZLT ) traded higher for the third straight session on Wednesday after Citizens JMP Securities upgraded the stock, highlighting a recent late-stage trial update the company shared for its lead asset, ersodetug. Shares of the rare-disease drug…
Jun 3, 11:09 AM EDT
IDEAYA to work with Roche on combo pancreatic cancer treatment
IDYARHHBY
IDEAYA Bioscience ( IDYA ) and Roche ( RHHBY ) have agreed to jointly evaluate a combination of the former's IDE892 with the latter's RG6505 for MTAP-deleted RAS-mutant pancreatic cancer. Both assets are in phase 1. IDE892 is an MTA-cooperative PRMT5 inhibitor…
Jun 3, 9:52 AM EDT
CytomX gains as licensing deal with Regeneron expands
REGNCTMX
CytomX Therapeutics ( CTMX ) traded higher in the morning hours on Wednesday after the cancer drug developer announced an expanded collaboration and licensing agreement with Regeneron Pharmaceuticals ( REGN ) valued up to $4B. Two companies initially teamed up…
Jun 3, 9:45 AM EDT
Most and least shorted healthcare stocks with market cap up to $2B at the end of May
XLVQUCYIBBPPH
Short interest data from late May indicates varying investor feelings in the healthcare sector, with strong bearish bets concentrated on micro- and small-cap biotechnology names like Quantum Cyber ( QUCY ) and Sensei Biotherapeutics ( SNSE ). Meanwhile, niche…
Jun 3, 9:35 AM EDT
Most and least shorted mid- to mega-cap healthcare stocks at the end of May
XLVRXRXIBBPPH
iQoncept/iStock via Getty Images Short interest data from late May indicates varying investor feelings in the healthcare sector, with strong bearish bets concentrated on speculative biotech plays like Recursion Pharmaceuticals ( RXRX ) and Hims & Hers ( HI…
Jun 3, 9:14 AM EDT
Liminatus Pharma secures $1.9M cash via warrant exercises
LIMNLIMNW
Liminatus Pharma ( LIMN ) has entered into a warrant exercise agreement to exercise certain outstanding warrants to purchase an aggregate of 10.34M shares of common stock of the company for gross proceeds of $1.9M. In consideration for the immediate exercise o…
Jun 3, 9:04 AM EDT
LIXTE Biotechnology prices $16.6M registered direct offering
LIXT
LIXTE Biotechnology Holdings ( NASDAQ: LIXT ) on Wednesday said it entered into definitive agreements with accredited investors for a registered direct offering expected to raise approximately $16.6 million in gross proceeds. The offering consists of 2.63 mill…
Jun 3, 7:41 AM EDT
Celcuity announces $400M convertible notes offering
CELC
Celcuity ( NASDAQ: CELC ) on Wednesday said that it plans to offer $400 million of convertible senior notes due 2032 in an underwritten public offering. The clinical-stage biotechnology company said it expects to grant underwriters a 30-day option to purchase…
Jun 3, 6:36 AM EDT
Restart Life Sciences names Inez Ho CFO; Rebecca Hudson resigns
NMLSF
Restart Life Sciences ( NMLSF ) has appointed Inez Ho as CFO, effective immediately. Ho succeeds Rebecca Hudson, who has resigned from her role to pursue other commitments. Bringing over 12 years of corporate compliance, financial reporting, and capital market…
Jun 3, 6:31 AM EDT
Mineralys Therapeutics prices $150M stock offering
MLYS
Mineralys Therapeutics ( MLYS ) has priced an offering of 5.66M shares of its common stock at a price of $26.50 per share. The gross proceeds from the offering are expected to be around $150M. Mineralys plans to use the net proceeds to fund a
Jun 3, 3:54 AM EDT
Tang Capital takes 10% stake in Aurinia Pharma
AUPH
Tang Capital Management Tuesday said that it acquired 206,005 common shares of Aurinia Pharmaceuticals ( AUPH ) at a price of $15.28 per share for an aggregate purchase price of $3.1M. As a result of the purchase, Tang Capital Management, LLC beneficially owns…
Jun 2, 1:50 PM EDT
Draft FDA guidance could be a boon for gene therapy developers
CRSPNTLACMCKRYS
narvo vexar The US FDA has issued draft guidance intended to accelerate the development of gene and cell therapies. The agency hopes the document will enhance the R&D process for the treatments " by making greater use of existing scientific and regulatory
Jun 2, 1:29 PM EDT
Amgen wins EU approval for Imdylltra in small cell lung cancer
AMGN
Amgen ( AMGN ) has received marketing authorization from the European Commission to market its FDA-approved antitumor agent Imdelltra, also known as tarlatamab, as a late-line option in the EU for adults with certain types of small cell lung cancer. Specifical…