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Alumis Inc

ALMS
Healthcare|Biotechnology|USA
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Clinical Trials (13)

TrialConditionsPhaseStatusEnrollmentDesignDrug
NCT06846541
Long-term Safety and Efficacy of ESK-001 in Moderate to Severe Plaque Psoriasis
Plaque Psoriasis, Psoriasis (PsO)
P3
Active1,680RCT, Double-blindOpen-Label Envudeucitinib, Blinded Envudeucitinib, Placebo
NCT05966480
Phase 2 Placebo-Controlled Study to Assess the Safety and Efficacy of ESK-001 in Active Systemic Lupus Erythematosus
SLE
P2
Active408RCT, Double-blindEnvudeucitinib, Placebo
NCT05739435
Open-Label Extension Study to Evaluate the Long Term Safety and Efficacy of ESK-001 in Plaque Psoriasis
Plaque Psoriasis
P2
Active165RCT, Open-labelenvudeucitinib
NCT06588738
A Study in Patients With Moderate to Severe Plaque Psoriasis to Evaluate the Efficacy and Safety of ESK-001
Plaque Psoriasis
P3
Completed862RCT, Double-blindEnvudeucitinib, Placebo, Apremilast
NCT06586112
A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Moderate to Severe Plaque Psoriasis
Plaque Psoriasis
P3
Completed912RCT, Double-blindEnvudeucitinib, Apremilast, Placebo
NCT05600036
A Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Plaque Psoriasis
Plaque Psoriasis
P2
Completed228RCT, Double-blindESK-001, Placebo
NCT05953688
POC Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Active Intermediate, Posterior, or Pan NIU
Uveitis Posterior Non-Infectious, Uveitis, Intermediate
P2
Terminated36RCT, Double-blindESK-001
NCT05431634
Multiple Dose Study to Determine Safety and Tolerability of ESK-001 in Healthy Participants
Safety and Tolerability
P1
Completed49RCT, Double-blindExperimental drug: ESK-001
NCT05330858
Relative Bioavailability of ESK-001 Tablet Versus Liquid in Healthy Participants
Pharmacokinetics
P1
Completed14RCT, Open-labelESK-001, Rabeprazole
NCT07442149
An Investigational Study to Evaluate the Safety and Tolerability of Single and Multiple Ascending Doses of A-005
Healthy Volunteer
P1
Completed135RCT, Double-blindA-005, A-005, Placebo
NCT07378579
An Investigational Study to Evaluate the Cardiac Safety Assessment (TQTc Study) of ESK-001
Healthy Volunteer
P1
Completed52RCT, Double-blindESK-001, Moxifloxacin (400 mg), Placebo
NCT06962774
An Investigational Study of ESK-001 in Participants With Normal Renal Function and Participants With Mild, Moderate, and Severe Impaired Renal Function
Renal Impairment
P1
Completed16Single-blindESK-001
NCT06952634
An Investigational Study of ESK-001 in Participants With Normal Liver Function and Participants With Mild, Moderate, and Severe Liver Damage
Hepatic Impairment
P1
Completed32Open-labelenvudeucitinib