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Annovis Bio, Inc.

ANVS
Healthcare|Biotechnology|US
$0.84
+0.18 (+26.31%)
DCF Value
$0.84
Cash / Share
$0.50

About

Annovis Bio, Inc. is a clinical-stage biopharmaceutical company focused on pioneering treatments for neurodegenerative disorders. The firm's flagship drug, Buntanetap, an oral medication, has successfully advanced through Phase 2a clinical trials for Alzheimer's and Parkinson's diseases. This compound is also currently being evaluated in clinical studies for Alzheimer's disease in individuals with Down Syndrome, as well as for various other chronic neurodegenerative conditions. Beyond Buntanetap, Annovis Bio is developing ANVS405 to offer protection against traumatic brain injury and stroke. Additionally, ANVS301 is progressing through Phase I clinical trials, aiming to enhance cognitive capabilities in the later stages of Alzheimer's disease and broader dementia. The company was founded in 2008 and operates out of Berwyn, Pennsylvania.

Stock Price

-57.5%(1Y)
1M
-27.8%
3M
-55.1%
6M
-62.9%
YTD
-75.6%
1Y
-57.5%
3Y
-84.8%
5Y
-97.8%

Pipeline Summary

8 total trials
3
Phase 1
5
Phase 2
5
Phase 3
0
Phase 4
Completed: 4Recruiting: 1Terminated: 1Not Yet Recruiting: 1Active: 1

Active Trials (2)

A Study of Buntanetap in Participants With PD
NCT07284784Parkinson's Disease (PD)
Phase 2Phase 3Recruiting
Enrollment: 500 participants
A Double-blind Dual Study Assessing Safety and Efficacy of Buntanetap in Participants With Early AD
NCT06709014Early Alzheimers Disease
Phase 3Active
Enrollment: 760 participants

Key Facts

Market Cap$36.1M
Employees8 (+0% YoY)
CEOMaria L. Maccecchini
IPO DateJan 29, 2020
Beta1.35
52-Week Range$0.6161 – $5.5
Avg Volume1,358,384
ExchangeNYSE

Ownership

Float88.2%
Shares Outstanding42.7M

Recent Insider Trades

Hoffman Michael BBUY
Nov 6, 20265,000,000 shares @ $1.00
Hoffman Michael BBUY
Nov 6, 20265,000,000 shares @ $1.00
Hoffman Michael BBUY
May 20, 202654,933 shares @ $1.90
Hoffman Michael BBUY
May 20, 202618,849 shares @ $1.80
Hoffman Michael BBUY
May 20, 20262,562 shares @ $1.75

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Data last updated: Nov 9, 2026, 03:55 AM