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Autolus Therapeutics plc

AUTL
Healthcare|Biotechnology|GB
$1.28
+0.02 (+1.59%)
Tangible Book / Share
$0.21
Cash / Share
$0.76

About

Autolus Therapeutics plc is a clinical-stage biopharmaceutical entity primarily focused on pioneering T-cell-based immunotherapies for various oncological conditions. The company's pipeline includes several investigational programs: obecabtagene autoleucel (AUTO1), a CD19-targeting programmed T cell therapy, is currently undergoing Phase 1b/2 trials for adult acute lymphoblastic leukemia (ALL). Additionally, AUTO1/22 is in a Phase 1 study for pediatric patients experiencing relapsed or refractory ALL. Autolus is also advancing AUTO4, a programmed T cell therapy designed to target TRBC1 for the treatment of peripheral T-cell lymphoma, and AUTO8, a product candidate currently in Phase I clinical trials for multiple myeloma. In earlier development, AUTO6NG, a programmed T cell therapy, is in preclinical research targeting GD2 for neuroblastoma, and AUTO5 is another hematological product candidate in its preclinical stages. Established in 2014, Autolus Therapeutics maintains its headquarters in London, United Kingdom.

Stock Price

-5.9%(1Y)
1M
-27.7%
3M
-39.3%
6M
-18.5%
YTD
-35.7%
1Y
-3.0%
3Y
-65.4%
5Y
-81.6%

Pipeline Summary

13 total trials
8
Phase 1
9
Phase 2
0
Phase 3
0
Phase 4
Recruiting: 5Completed: 1Active: 2By Invitation: 1Terminated: 3Available: 1

Active Trials (7)

Obe-cel in Severe, Refractory Systemic Lupus Erythematosus (SLE) With Active Lupus Nephritis (LN)
NCT07053800Lupus Nephritis
Phase 2Recruiting
Enrollment: 35 participants
Obe-cel in Adolescent [Applicable in UK Only] and Adult Severe, Refractory Systemic Lupus Erythematosus
NCT06333483Systemic Lupus Erythematosus
Phase 1Active
Enrollment: 16 participants
A Study of CD19 Targeted CAR T Cell Therapy in Adult Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukaemia (ALL)
NCT04404660Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia
Phase 1Phase 2Active
Enrollment: 153 participants
Phase 2 Study Assessing the Clinical Activity and Safety of Obecabtagene Autoleucel as a Consolidation in Patients With Newly Diagnosed High-risk B-cell Acute Lymphocytic Leukemia (ALL)
NCT07053059Acute Lymphocytic Leukemia (ALL)
Phase 2Recruiting
Enrollment: 30 participants
Obe-cel in Refractory Progressive Forms of Multiple Sclerosis
NCT07139743Progressive Multiple Sclerosis
Phase 1Recruiting
Enrollment: 24 participants

Key Facts

Market Cap$340.7M
Employees752 (+16% YoY)
CEOChristian Martin Itin
IPO DateJun 22, 2018
Beta2.35
52-Week Range$1.175 – $2.58
Avg Volume2,050,972
ExchangeNASDAQ

Ownership

Float90.4%
Shares Outstanding266.2M

Recent Insider Trades

Piccina CintiaOPTION EX.
Sep 1, 202620,000 shares
Piccina CintiaOPTION EX.
Sep 1, 202620,000 shares @ $2.35
Piccina CintiaSELL
Sep 2, 20266,713 shares @ $2.34
YOUNG WILLIAM DAWARD
Jun 29, 202647,500 shares @ $1.61
YOUNG WILLIAM DAWARD
Jun 29, 202631,667 shares

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Data last updated: Nov 9, 2026, 03:57 AM