Cognition Therapeutics, Inc.
CGTXHealthcare|Biotechnology|US
$0.69
+0.05 (+8.12%)
DCF Value
$0.60
Tangible Book / Share
$0.31
Cash / Share
$0.32
Clinical Trials (89)
| Trial | Conditions | Phase | Status | Enrollment | Design | Drug |
|---|---|---|---|---|---|---|
| NCT07633470 A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE) | Alzheimer Disease | P4 | Recruiting | 150 | Open-label | Zunveyl® |
| NCT06778564 Stratification and Treatment in Early Psychosis Study - ENHANCE | Psychosis, First Episode Psychosis | P3 | Recruiting | 250 | RCT, Double-blind | CBD 100 mg/mL Oral Solution |
| NCT07523048 Dextromethorphan-Bupropion on Striatal Activity in Adults With Major Depressive Disorder | Major Depressive Disorder (MDD) | P2 | Recruiting | 30 | Open-label | Dextromethorphan-Bupropion |
| NCT05531656 A Study to Evaluate the Safety and Efficacy of CT1812 in Early Alzheimer's Disease | Early Alzheimer's Disease | P2 | Active | 540 | RCT, Double-blind | CT1812, Placebo |
| NCT07274722 Influence of Control Deprivation on the Use of the Analytical Cognitive Style in Anorexic Subjects | Anorexia Nervosa | N/A | Recruiting | 54 | Open-label | — |
| NCT06591780 Innovative Multi-Variable Biofeedback for Improving Gait Performance in Individuals With Diabetic Peripheral Neuropathy | Diabetic Peripheral Neuropathy, Diabetes Mellitus | N/A | Recruiting | 25 | Open-label | — |
| NCT07531706 Cortical Tracking of Speech in the First Year of Life | Language Development, Language Development Disorders | Recruiting | 50 | — | — | |
| NCT05965336 Walking Function in Diabetic Peripheral Neuropathy | Diabetic Peripheral Neuropathy | N/A | Recruiting | 50 | RCT, Open-label | — |
| NCT07846618 Acute Mental Fatigue and Muscle Strength | Mental Fatigue, Muscle Strength Dynamometer | N/A | Recruiting | 50 | Open-label | — |
| NCT07064291 Enhancing Self-Esteem in Patients With Multiple Sclerosis: A Randomised Controlled Trial of the Lexical Association Technique | Multiple Sclerosis, Quality of Life (QOL) | N/A | Recruiting | 160 | RCT, Double-blind | — |
| NCT06507189 Multidimensional Predictive Modeling to Understand Mechanisms of Exercise Response Heterogeneity in Older Adults (M3AX) | Aging, Aging Well | N/A | Recruiting | 250 | RCT, Double-blind | — |
| NCT07531732 Links Between Self-awareness and Sociocognitive Processes in Neurodegenerative Diseases | Frontotemporal Dementia, Behavioral Variant, Alzheimer Disease | Recruiting | 34 | — | — | |
| NCT06105645 Contribution of Fast-ripples to the Improvement of the Neurosurgical Management of Drug-refractory Epilepsy | Epilepsy | N/A | Recruiting | 440 | Open-label | — |
| NCT07418905 Technology-supported Motor Rehabilitation for People With Rett Syndrome | Rett Syndrome | N/A | Active | 14 | Open-label | — |
| NCT07326124 Stratification and Treatment in Early Psychosis Study -ASSIST | Treatment Resistant Psychosis, Psychosis | P3 | Not Yet Recruiting | 250 | RCT, Double-blind | CBD 100 mg/mL Oral Solution, Placeb |
| NCT03053362 THINC-it Vortioxetine - Sensitivity to Change | Major Depressive Disorder, Cognitive Change | P2P3 | Completed | 158 | Open-label | Vortioxetine |
| NCT05948553 Department of Defense PTSD Adaptive Platform Trial - Intervention A - Fluoxetine | Post Traumatic Stress Disorder | P2 | SUSPENDED | 200 | RCT, Double-blind | Intervention A Fluoxetine Hydrochloride (HCl), Intervention A Placebo |
| NCT05047952 Vortioxetine for Post-COVID-19 Condition | Post-COVID-19 Condition, Post-COVID-19 Syndrome | P2 | Completed | 149 | RCT, Double-blind | Vortioxetine, Placebo |
| NCT02907567 Clinical Trial of CT1812 in Mild to Moderate Alzheimer's Disease | Alzheimer's Disease | P1P2 | Completed | 19 | RCT, Double-blind | CT1812, Placebo |
| NCT07432997 Pharmacological Enhancement of Glymphatic Function in Humans | Alzheimer Disease | P1P2 | Completed | 31 | Double-blind | Dexmedetomidine, Dexmedetomidine and Midodrine |
| NCT04738838 Oxytocin on Cold Water Task Performance and Recovery | Cold Exposure | P2 | Completed | 17 | RCT, Double-blind | Oxytocin nasal spray, Placebo nasal spray |
| NCT05893537 Study to Evaluate the Efficacy and Safety of Oral CT1812 in Participants With Geographic Atrophy (GA) Secondary to Dry Age-Related Macular Degeneration (AMD). | Age-Related Macular Degeneration | P2 | Terminated | 100 | RCT, Double-blind | Active Comparator CT1812, Placebo Comparator |
| NCT04732247 Oxytocin for Oxidative Stress and Inflammation | Oxidative Stress, Inflammation | P2 | Completed | 40 | RCT, Double-blind | Oxytocin nasal spray, Placebo nasal spray |
| NCT05948579 Department of Defense PTSD Adaptive Platform Trial - Intervention B - Vilazodone | Post Traumatic Stress Disorder | P2 | Not Yet Recruiting | 200 | RCT, Double-blind | Intervention B Vilazodone Hydrochloride (HCl), Intervention B Placebo |
| NCT05225415 Study to Evaluate the Safety, Tolerability and Efficacy of CT1812 in Subjects With Mild to Moderate Dementia With Lewy Bodies | Dementia With Lewy Bodies | P2 | Completed | 130 | RCT, Double-blind | CT1812 |
| NCT03143634 The Modular Protocol for Mental Health (MPMH) | Major Depressive Disorder, Generalized Anxiety Disorder | P1P2 | Completed | 43 | RCT, Single-blind | — |
| NCT03507790 A Study to Evaluate the Safety and Efficacy of CT1812 in Subjects With Mild to Moderate Alzheimer's Disease. | Mild to Moderate Alzheimer's Disease | P2 | Completed | 153 | RCT, Double-blind | CT1812, Placebo |
| NCT07304843 A Two-part Study to Investigate the Effects in Adults of Two Doses of Golexanolone in Patients With Primary Biliary Cholangitis (PBC) With Fatigue and Cognitive Dysfunction | Primary Biliary Cholangitis (PBC) | P1P2 | Completed | 207 | RCT, Double-blind | golexanolone, golexanolone, Placebo, golexanolone, Placebo |
| NCT00529581 A Study of C105 on Cognitive Dysfunction in Persons With Multiple Sclerosis | Cognition Disorders, Multiple Sclerosis | P2 | Completed | 150 | RCT, Double-blind | C105 |
| NCT02614326 MemFlex to Prevent Depressive Relapse | Major Depressive Disorder | P2 | Completed | 70 | RCT, Single-blind | — |
| NCT02371291 Memory Flexibility Training for Depression | Major Depressive Disorder | P1P2 | Completed | 60 | RCT, Single-blind | — |
| NCT06816433 Department of Defense PTSD Adaptive Platform Trial - Intervention D - SLS-002 | Post Traumatic Stress Disorder | P2 | SUSPENDED | 200 | RCT, Double-blind | Intervention D SLS-002, Intervention D Placebo |
| NCT05422612 Department of Defense PTSD Adaptive Platform Trial - Master Protocol | Post Traumatic Stress Disorder | P2 | SUSPENDED | 800 | RCT, Double-blind | Intervention A Fluoxetine Hydrochloride (HCl), Intervention A Placebo, Intervention B Vilazodone Hydrochloride (HCl), Intervention B Placebo, Intervention C Daridorexant, Intervention C Placebo, Intervention D SLS-002, Intervention D Placebo |
| NCT05948540 Department of Defense PTSD Adaptive Platform Trial - Intervention C - Daridorexant | Post Traumatic Stress Disorder | P2 | SUSPENDED | 200 | RCT, Double-blind | Intervention C Daridorexant, Intervention C Placebo |
| NCT03493282 Effect of CT1812 Treatment on Brain Synaptic Density | Alzheimer Disease | P1P2 | Completed | 43 | RCT, Double-blind | Active Treatment- CT1812 100 mg, Active Treatment- CT1812 300 mg, Placebo |
| NCT05029466 Psilocybin for Treatment-Resistant Depression | Treatment Resistant Depression | P2 | Completed | 30 | RCT, Open-label | Psilocybin |
| NCT04735536 Pilot Clinical Study of CT1812 in Mild to Moderate Alzheimer's Disease Using EEG | Alzheimer Disease | P2 | Completed | 16 | RCT, Double-blind | CT1812 |
| NCT02570997 Ascending Dose Study of CT1812 in Healthy Volunteers | Cognitive Impairment | P1 | Completed | 80 | RCT, Double-blind | CT1812, Placebo |
| NCT06194864 Drug Interaction Study | Drug Interaction | P1 | Completed | 45 | Open-label | Itraconazole, rifampicin, Ecopipam |
| NCT03716427 Drug Interaction Study of CT1812 in Healthy Volunteers | Healthy Volunteers | P1 | Completed | 16 | Open-label | CT1812, tolbutamide, dextromethorphan, Omeprazole, midazolam |
| NCT03522129 Study to Evaluate the Effect of CT1812 Treatment on Amyloid Beta Oligomer Displacement Into CSF in Subjects With Mild to Moderate Alzheimer's Disease | Alzheimer Disease | P1 | Completed | 3 | RCT, Double-blind | CT1812, Placebo |
| NCT05225389 Study to Assess the Absorption, Metabolism, Excretion, and Mass Balance of CT1812 in Healthy Adult Male Subjects | Alzheimer Disease | P1 | Completed | 8 | Open-label | 300 mg [C14] CT1812 |
| NCT05248672 Study to Assess the Pharmacokinetics of CT1812 in Older Healthy Volunteers | Alzheimer Disease | P1 | Completed | 35 | RCT, Double-blind | CT1812 |
| NCT05753605 My Experiences: Leveraging Digital Technologies to Better Understand Mental Health | Mental Health Symptoms, Wearables | Completed | 302 | — | — | |
| NCT06060054 Continuous Measurement of Glymphatic Activity in the Human Brain During Sleep-Wake States | Healthy | N/A | Completed | 15 | RCT, Single-blind | — |
| NCT03661190 Online Grammatical Reasoning Training for Older Adults | Healthy Aging | N/A | Completed | 6,544 | RCT, Single-blind | — |
| NCT03659825 Ketone Esters for Optimization of Cognitive Performance in Hypoxia | Hypoxia, Ketosis | N/A | Unknown | 16 | RCT, Double-blind | — |
| NCT02590796 Validating Studies to Assess the Diagnostic Accuracy of a Software Application for Detection and Monitoring of Attentional Deficits in Delirium | Delirium, Dementia | Completed | 907 | — | — | |
| NCT01898390 TRANSEURO Open Label Transplant Study in Parkinson's Disease | Parkinson's Disease | N/A | Completed | 13 | RCT, Open-label | — |
| NCT04209296 Chart Review of Patients Undergoing Ketamine Infusions | Major Depressive Disorder, Bipolar Disorder | Completed | 891 | — | Ketamine Hydrochloride | |
| NCT03634709 Autobiographical Memory Flexibility Training (MemFlex) for Posttraumatic Stress Disorder | Post Traumatic Stress Disorder | N/A | Completed | 40 | RCT, Single-blind | — |
| NCT02080351 A Simple Cognitive Task to Reduce the Build-Up of Flashbacks After a Road Traffic Accident | Post-traumatic Stress Disorders | N/A | Completed | 71 | RCT, Open-label | — |
| NCT04513743 Ultra Long-Term Sleep Monitoring Using UNEEG™ Medical 24/7 EEG™ SubQ | Sleep | N/A | Completed | 25 | Open-label | — |
| NCT01070004 Effect of Countermeasures on Nocturnal Driving Performance | Sleepiness | N/A | Completed | 72 | Open-label | — |
| NCT04713111 Stress and Recovery in Frontline COVID-19 Workers | Covid19, Stress | N/A | Completed | 383 | Open-label | — |
| NCT07500909 Study of the Role of Top-down Processes in Neuronal Reorganization and Recovery From Sensory Loss: an Exploratory Behavioral and Electroencephalographic Study in Cochlear-supported Deaf Patients | Deafness, Bilateral | Not Yet Recruiting | 90 | — | — | |
| NCT05563597 Cognitive Monitoring in Planned Arthroplasty Surgery | Cognitive Change | Completed | 117 | — | — | |
| NCT03538158 A Personalized Health Behavior System | Social Isolation, Aging | N/A | Completed | 181 | RCT, Double-blind | — |
| NCT02286505 Automated Brain Morphometry for Dementia Diagnosis | Dementia | N/A | Unknown | 80 | RCT, Open-label | — |
| NCT04180709 CBT to Reduce Insomnia and Improve Social Recovery in Early Psychosis | Psychotic Disorders, Psychosis | N/A | Completed | 45 | RCT, Open-label | — |
| NCT03117413 Positron Emission Tomography Imaging of Brain Reorganisation of the Central Auditory Cortex in Asymetrical Profound Deaf Patient With a Cochlear Implantation. | Profound Hearing Impairment | N/A | Completed | 20 | Open-label | — |
| NCT07814534 Synthetic Vasomotion for Glymphatic Enhancement | Parkinson Disease (PD) | N/A | Not Yet Recruiting | 20 | RCT, Single-blind | — |
| NCT02416245 Impact of Beverage Powder With Micronutrients and Brahmi Extract on Cognitive Variables in Indian School Children | Cognition | N/A | Completed | 310 | RCT, Double-blind | — |
| NCT07866794 Group Transdiagnostic Cognitive Behavioural Therapy for Intolerance of Uncertainty Versus Applied Relaxation | Mental Disorders, Mood Disorders | N/A | Not Yet Recruiting | 135 | RCT, Single-blind | — |
| NCT04714905 Better Understanding the Metamorphosis of Pregnancy (BUMP) | Pregnancy Related, Pregnancy Early | Completed | 712 | — | — | |
| NCT01946607 Antidepressants, Emotions and Personality | Antidepressive Agents, Second-Generation | N/A | Completed | 42 | RCT, Double-blind | Citalopram, Placebo |
| NCT02603380 Feasibility of a Software App for Testing Inattention in Delirium | Delirium | Completed | 48 | — | — | |
| NCT07572266 Adjuvant Nitrate to Boost Exercise-induced Health Benefits in Older Adults | Aging, Aging Well | N/A | Not Yet Recruiting | 226 | RCT, Double-blind | — |
| NCT03012685 Sleep and Wellbeing Study | Sleep, Intrusive Memories | Completed | 100 | — | — | |
| NCT01981018 MAPP: Imagery-focused Therapy for Bipolar Disorder | Bipolar Disorder | N/A | Completed | 15 | Open-label | — |
| NCT07830745 Effects of Optokinetic Stimulation Without a Reading Task in Patients With Hemianopic Alexia | Hemianopia Homonymous, Stroke | N/A | Not Yet Recruiting | 30 | RCT, Single-blind | — |
| NCT07862244 A Grief Support App for Adults Experiencing Bereavement | Grief | N/A | Not Yet Recruiting | 80 | RCT, Open-label | — |
| NCT04695405 Pharmacogenetics Associated With IV Ketamine | Treatment Resistant Depression | Completed | 85 | — | — | |
| NCT06222385 Applied Cognition Benchmarking Study | Healthy | N/A | Completed | 34 | RCT, Single-blind | — |
| NCT03999567 Validation Study: Mobile DSST on Cognition in Adults With MDD | Major Depressive Episode | N/A | Completed | 30 | Open-label | — |
| NCT04161261 Minimizing Facial Nerve Stimulation in Cochlear Implants | Cochlear Hearing Loss, Hearing Loss, Sensorineural | N/A | Unknown | 24 | Open-label | — |
| NCT04631302 The Work Engagement and Wellbeing Study | Mindfulness, Exercise | N/A | Completed | 241 | RCT, Single-blind | — |
| NCT03776513 Neuro-cognitive Impact of Juvenile Obesity | Pediatric Obesity, Behavior and Behavior Mechanisms | N/A | Terminated | 30 | Open-label | — |
| NCT02053207 Feasibility Study of Preoperative Cognitive Training in Cardiac Surgical Patients | Postoperative Cognitive Dysfunction | N/A | Unknown | 10 | Open-label | — |
| NCT02597686 The STAGE Study for Bipolar Disorder | Bipolar Disorder | N/A | Unknown | 12 | Open-label | — |
| NCT03238001 Evaluation of DCTclock™ as a Cognitive Assessment Aid | Cognitive Function | N/A | Completed | 450 | Open-label | — |
| NCT02502513 Prevention of Intrusive Memories and Posttraumatic Stress Symptoms After Emergency Cesarean Section | Posttraumatic Stress Disorder, Acute Stress Disorder | N/A | Completed | 56 | RCT, Open-label | — |
| NCT07512375 The Effectiveness of an ETP Programme in Myasthenia Gravis: a Proof-of-concept Study. | Myasthenia Gravis (MG) | Not Yet Recruiting | 62 | — | — | |
| NCT03923569 Epileptiform Activity During REM Sleep in Alzheimer's Disease | Alzheimer Disease, Early Onset | N/A | Unknown | 62 | Open-label | — |
| NCT06961760 Expanded Access Program for CT1812 (Zervimesine) | Dementia With Lewy Bodies | NO_LONGER_AVAILABLE | — | — | zervimesine | |
| NCT02508493 Validation of the THINC-it Tool for Cognitive Dysfunction in Major Depressive Disorder | Major Depressive Disorder | Completed | 200 | — | — | |
| NCT07065864 Ketone Esters for Optimization of Operator Performance in Hypoxia | Hypoxia | N/A | Completed | 17 | RCT, Single-blind | — |
| NCT03939676 Evaluating Motivation and Reward Mechanisms and Brain Substrates in Adults With Obesity | Anhedonia, Obesity | Completed | 12 | — | — | |
| NCT02675075 DESIPHER_Speech Degradation as an Indicator of Physiological Degeneration in ALS | Amyotrophic Lateral Sclerosis | Completed | 34 | — | — |