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Coherus Oncology, Inc.

CHRS
Healthcare|Biotechnology|US
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Clinical Trials (28)

TrialConditionsPhaseStatusEnrollmentDesignDrug
NCT06457503
A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer
Nasopharyngeal Cancer Recurrent
P4
Recruiting100Open-labelToripalimab, Cisplatin, Gemcitabine, Carboplatin
NCT07140679
Immunotherapy (Toripalimab) for Reducing Recurrence Risk After Surgery for Mismatch Repair Deficient Stage IIB, IIC, or III Colon Cancer
Localized Colon Carcinoma, Stage IIB Colon Cancer AJCC v8
P2
Recruiting40Open-labelToripalimab
NCT07214987
PDT For Induction Therapy For Head And Neck Cancer
Squamous Cell Carcinoma, Head and Neck Cancer Squamous Cell Carcinoma
P2
Recruiting26Open-labelToripalimab-tpzi, Cisplatin, Docetaxel
NCT06940180
Toripalimab With Chemotherapy for Sinus Cancer
Sinonasal Cancer, Paranasal Sinus Neoplasms
P2
Recruiting20Open-labelToripalimab, Carboplatin, Docetaxel, Cisplatin
NCT06975293
STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas
Solid Tumor, Sarcoma
P1P2
Recruiting107Open-labelSTC-15 in combination with toripalimab, STC-15 monotherapy
NCT07423078
Window of Opportunity in Preserving Laryngeal Function Trial
Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M), Locally Advanced Laryngeal Squamous Cell Carcinoma
P2
Recruiting87Open-labelToripalimab, Carboplatin, Cisplatin, Paclitaxel
NCT06679985
A Trial of Casdozokitug in Combination With Toripalimab Plus Bevacizumab in Participants With Unresectable and/or Locally Advanced or Metastatic Hepatocellular Carcinoma
Hepatocellular Carcinoma
P2
Active72RCT, Open-labelCasdozokitug, Toripalimab, Bevacizumab
NCT07281716
Combination Immunotherapy for the Treatment of Chemotherapy-refractory Metastatic MSS CRC
Metastatic Microsatellite Stable Colorectal Carcinoma
P1P2
Recruiting24Open-labelNadunolimab, Toripalimab
NCT07277322
Neoadjuvant Dupilumab and Toripalimab in MSS CRC Subjects With Resectable Liver Metastases
Metastatic Colorectal Cancer, Liver Metastases
P1P2
Recruiting24Open-labelDupilumab, Toripalimab
NCT07209189
Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN)
Head and Neck Cancer, Squamous Cell Carcinoma
P2
Recruiting75Open-labelToripalimab + Chemotherapy, Toripalimab
NCT05635643
Study of CHS-114 in Participants With Advanced Solid Tumors
Advanced Solid Tumor, Head and Neck Squamous Cell Carcinoma
P1
Active87RCT, Open-labelCHS-114, toripalimab
NCT06657144
A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors
Metastatic Solid Tumor, Advanced Solid Tumor
P1
Recruiting154RCT, Open-labelCHS-114, Toripalimab, 5 Fluorouracil, Cisplatin
NCT02486939
A Long Term Safety Extension Study (CHS-0214-05)
Rheumatoid Arthritis, Plaque Psoriasis
P3
Completed359Open-labelCHS-0214
NCT02134210
Comparison of CHS-0214 to Enbrel (Etanercept) in Patients With Chronic Plaque Psoriasis (PsO)
Plaque Psoriasis
P3
Completed521RCT, Double-blindEtanercept, CHS-0214
NCT02115750
Comparison of CHS-0214 to Enbrel (Etanercept) in Patients With Rheumatoid Arthritis (RA)
Rheumatoid Arthritis
P3
Completed647RCT, Double-blindEtanercept, CHS-0214
NCT02489227
Comparison of CHS-1420 Versus Humira in Subjects With Chronic Plaque Psoriasis
Plaque Psoriasis
P3
Completed545RCT, Double-blindCHS-1420, Adalimumab
NCT05359861
Trial of Atezolizumab and Bevacizumab With CHS-388 or Placebo in Patients With Hepatocellular Carcinoma
Hepatocellular Carcinoma
P2
Terminated30RCT, Double-blindCasdozokitug, Atezolizumab, Bevacizumab, Placebo
NCT05479045
A Combination Therapy Strategy to Prevent Anti-PD-1 Therapy Resistance in Metastatic Ovarian Cancer Patients
Ovarian Cancer Stage IV, Ovarian Cancer Stage III
P2
Withdrawn—Open-labelNY-ESO-1 Peptide vaccine, Toripalimab-tpzi
NCT07836049
PhII Study of Toripalimab Followed by Definitive CRT & Adjuvant Toripalimab in Locally Advanced ESCC
Esophageal Squamous Cell Carcinoma
P2
Not Yet Recruiting20Open-labelToripalimab, Carboplatin + Paclitaxel
NCT05177770
Study of SRF617 With AB928 (Etrumadenant) and AB122 (Zimberelimab) in Patients With Metastatic Castration Resistant Prostate Cancer
Metastatic Castration-resistant Prostate Cancer, Prostate Cancer
P2
Terminated16Open-labelSRF617, etrumadenant, zimberelimab
NCT04374877
Study of CHS-388 (Formerly Known as SRF388) in Patients With Advanced Solid Tumors
Advanced Solid Tumor, Clear Cell Renal Cell Carcinoma
P1
Completed145Open-labelCHS-388, Pembrolizumab, Toripalimab
NCT04336098
Study of SRF617 in Patients With Advanced Solid Tumors
Advanced Solid Tumor
P1
Completed85Open-labelSRF617, Gemcitabine, Albumin-Bound Paclitaxel, Pembrolizumab
NCT05757492
Study to Evaluate Safety and PK of CHS-006 in Combination With Toripalimab in Patients With Advanced Solid Tumors
Advanced Solid Tumor, Non-Small Cell Lung Cancer
P1
Terminated22RCT, Open-labelCHS-006 (anti-TIGIT), toripalimab (anti-PD-1)
NCT02650973
Study to Assess the Pharmacokinetic and Pharmacodynamic Bioequivalence of CHS-1701 With Neulasta
Healthy
P1
Completed122RCT, Single-blindCHS-1701, Pegfilgrastim
NCT02385851
Comparison of the Pharmacokinetic and Pharmacodynamic Biosimilarity of CHS-1701 (Coherus Pegfilgrastim) With Neulasta® (Pegfilgrastim)
Bioequivalence
P1
Completed116RCT, Double-blindCHS-1701, Pegfilgrastim
NCT06389526
A Study of CHS-1000 in Participants With Advanced or Metastatic Solid Tumors
Advanced or Metastatic Solid Tumors
P1
Not Yet Recruiting48Open-labelCHS-1000, Toripalimab
NCT02418104
Assessing the Immunogenicity of 2 Subcutaneous Doses of CHS-1701 (Coherus Pegfilgrastim) With 2 Subcutaneous Doses Neulasta®
Immunity, Humoral
P1
Completed303RCT, Double-blindCHS-1701, Pegfilgrastim (Neulasta)
NCT04662892
An Analysis to Estimate Febrile Neutropenia (FN) in Patients Receiving Udenyca
Febrile Neutropenia, Non-myeloid Malignancy
Unknown200—Pegfilgrastim-Cbqv