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Compass Therapeutics, Inc.

CMPX
Healthcare|Biotechnology|US
$0.76
+0.07 (+10.84%)
DCF Value
$0.12
Tangible Book / Share
$0.89
Cash / Share
$0.96

About

Compass Therapeutics, Inc. is a biopharmaceutical firm focused on developing cancer treatments, with several therapeutic candidates currently in clinical trials. The company's work involves creating antibody-based medicines designed to address a variety of human health conditions. Among its leading clinical-stage programs are CTX-009, an experimental bispecific antibody engineered to inhibit the Delta-like ligand 4/Notch and vascular endothelial growth factor A signaling pathways, both of which are crucial for the growth of new blood vessels and tumor vascularization. Another significant compound is CTX-471, an IgG4 monoclonal antibody that functions as an activator of CD137. Furthermore, their developmental pipeline features CTX-8371, a bispecific inhibitor that targets both PD-1 and PD-L1. The company was established in 2014 and operates from its headquarters in Boston, Massachusetts.

Stock Price

-81.0%(1Y)
1M
-22.8%
3M
-64.7%
6M
-58.5%
YTD
-85.9%
1Y
-82.3%
3Y
-55.9%
5Y
-79.7%

Pipeline Summary

29 total trials
6
Phase 1
19
Phase 2
5
Phase 3
0
Phase 4
Terminated: 2Recruiting: 6Not Yet Recruiting: 2Active: 3Completed: 12Withdrawn: 1Unknown: 3

Active Trials (9)

CTX-009 With Gemcitabine, Cisplatin, and Durvalumab as First-line Therapy in Patients With Unresectable or Metastatic Biliary Tract Cancers
NCT06548412Metastatic Biliary Tract Cancer
Phase 1Phase 2Recruiting
Enrollment: 50 participants
Safety and Efficacy of CTX-009 With or Without CTX-471 for Recurrent Glioblastoma
NCT07392957Glioblastoma
Phase 1Phase 2Recruiting
Enrollment: 54 participants
A Phase II, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of COMP360 in Participants With Recurrent Major Depressive Disorder
NCT05733546Major Depressive Disorder
Phase 2Active
Enrollment: 102 participants
A Study of CTX-009 in Combination With Paclitaxel in Adult Patients With Unresectable Advanced, Metastatic or Recurrent Biliary Tract Cancers (COMPANION-002)
NCT05506943Biliary Tract Cancer
Phase 2Phase 3Active
Enrollment: 168 participants
Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD
NCT05711940Treatment Resistant Depression
Phase 3Active
Enrollment: 572 participants

Key Facts

Market Cap$136.7M
Employees39 (+11% YoY)
CEOThomas J. Schuetz
IPO DateApr 5, 2021
Beta0.91
52-Week Range$0.671 – $6.88
Avg Volume3,711,176
ExchangeNASDAQ

Ownership

Float71.5%
Shares Outstanding180.1M

Recent Insider Trades

Lerner NeilBUY
Oct 1, 202620,000 shares @ $0.92
Lerner NeilBUY
Sep 24, 20262,500 shares @ $1.14
Lerner NeilBUY
Apr 29, 202615,000 shares @ $1.89
Anderman JonathanBUY
Apr 29, 202625,000 shares @ $1.89
Anderman JonathanAWARD
Apr 29, 202625,000 shares @ $1.89

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Data last updated: Nov 9, 2026, 04:02 AM