Collegium Pharmaceutical Inc
COLLHealthcare|Drug Manufacturers - Specialty & Generic|USA
$35.22
-0.59 (-1.65%)
DCF (FCF)
$54.10
Earnings Power
$22.35
Clinical Trials (37)
| Trial | Conditions | Phase | Status | Enrollment | Design | Drug |
|---|---|---|---|---|---|---|
| NCT05905965 Efficacy of Double vs Standard Empapagliflozin Dose for METabolic syndromE tReatment | Metabolic Syndrome | P3 | Recruiting | 200 | RCT, Open-label | Empagliflozin 20 mg, Empagliflozin 10 mg |
| NCT06442319 The Efficiency and Safety of PRP Treatment After Anterior Cruciate Ligament Reconstruction. | ACL Injury, Knee Osteoarthritis | N/A | Recruiting | 60 | RCT, Open-label | Platelet-rich plasma |
| NCT07593352 Renal Dysfunction in Patients With Inflammatory Bowel Disease and the General Population (NEPHRO-IBD) | IBD and Renal Involement, Chronic Kidney Disease | Recruiting | 6,000 | — | — | |
| NCT07231939 Use of Flozins (Empagliflozin/Dapagliflozin) for Prevention of AKI | Coronary Artery Disease, Acute Kidney Injury | Recruiting | 4,000 | — | Flozin | |
| NCT07153211 Analysis of Selected Biochemical Parameters in Cerebrospinal Fluid and Peripheral Blood in the Treatment of Neuropathic Pain Using Spinal Cord Stimulation (SCS) | Neuropathic Pain, Chronic Pain | N/A | Recruiting | 30 | Open-label | — |
| NCT03588806 Use of Xtampza ER to Overcome Difficulties in Swallowing Opioid Pills | Chronic Pain, Opioid Use | P4 | Terminated | 11 | Open-label | Xtampza ER (oxycodone) |
| NCT02612116 Comparison of Administration Strategies of Ticagrelor in Patients With Unstable Angina Pectoris, a Pharmacokinetic / Pharmacodynamic Study | Unstable Angina Pectoris | P4 | Completed | 49 | RCT, Open-label | Pulverized ticagrelor sublingually, Pulverized ticagrelor orally, Integral ticagrelor |
| NCT02217878 Influence of Morphine on Pharmacokinetics and Pharmacodynamics of Ticagrelor in Patients With Acute Myocardial Infarction | ST-segment Elevation Myocardial Infarction, Non-ST-segment Elevation Myocardial Infarction | P4 | Completed | 74 | RCT, Double-blind | Morphine, Placebo, Ticagrelor |
| NCT03764722 Effectiveness of a Repetitive Use of 24-hour Levosimendan Infusions in Patients With Severe Systolic Heart Failure in Order to Prevent Rehospitalizations | Systolic Heart Failure | P4 | Unknown | 100 | Open-label | Levosimendan |
| NCT04442919 Influence of METHoxyflurane on ANtiplatelet Effect of Ticagrelor in Patients With Unstable Angina Pectoris | Unstable Angina | P4 | Completed | 72 | RCT, Open-label | Ticagrelor followed with Methoxyflurane, Ticagrelor followed with Morphine, Ticagrelor alone |
| NCT02939235 Influence of Metoclopramide on Ticagrelor Pharmacokinetics and Pharmacodynamics in Patients With Unstable Angina Pectoris on Concomitant Treatment With Morphine | Unstable Angina Pectoris | P4 | Completed | 32 | RCT, Open-label | Crushed ticagrelor followed by morphine, Crushed ticagrelor, morphine,metoclopramide |
| NCT07203846 Modulation of Gut MicroFLORA With Rifaximin to Reduce High Platelet Reactivity in Post-ACS Patients on Ticagrelor | ACS - Acute Coronary Syndrome, Ticagrelor | P4 | Not Yet Recruiting | 50 | Open-label | Rifaximin |
| NCT02772640 Effectiveness of Treatment of Hypercholesterolemia With Rosuvastatin and Ezetimibe | Hypercholesterolemia | P4 | Completed | 83 | RCT, Open-label | Rosuvastatin and Ezetimibe morning or evening administration |
| NCT02939248 Influence of Naloxone on Ticagrelor Pharmacokinetics and Pharmacodynamics in Patients With Unstable Angina Pectoris on Concomitant Treatment With Morphine | Unstable Angina Pectoris | P4 | Completed | 30 | RCT, Open-label | Crushed ticagrelor followed by morphine, Crushed ticagrelor, morphine,naloxone |
| NCT01685684 Oxycodone DETERx™ Versus Placebo in Chronic Low Back Pain (CLBP) | Chronic Low Back Pain | P3 | Completed | 740 | RCT, Double-blind | Oxycodone DETERx, Placebo |
| NCT06431256 Efficacy, Safety & Pharmacokinetic (PK) Study of HLD200 in Children Aged 4-5 Years With ADHD | Attention Deficit Hyperactivity Disorder | P3 | Terminated | 26 | RCT, Double-blind | HLD200 methylphenidate hydrochloride capsules, Placebo HLD200 capsules |
| NCT04941105 Impact of PCSK9 Inhibition on Clinical Outcome in Patients During the Inflammatory Stage of the COVID-19 | Sars-CoV-2 Infection | P3 | Completed | 60 | RCT, Double-blind | Evolocumab, Saline solution |
| NCT05776043 Empagliflozin and Dapagliflozin in Patients Hospitalized for Acute Decompensated Heart Failure | Acute Decompensated Heart Failure | P3 | Unknown | 1,364 | RCT, Double-blind | Empagliflozin 10 MG, Dapagliflozin 10 MG, Placebo |
| NCT03251859 Effectiveness of Lower Maintenance Dose of Ticagrelor Early After Myocardial Infarction (ELECTRA) Pilot Study | Myocardial Infarction | P3 | Completed | 52 | RCT, Single-blind | Ticagrelor 90 mg, Ticagrelor 60 mg |
| NCT04718025 Evaluation of Safety and Efficacy of Two Ticagrelor-based De-escalation Antiplatelet Strategies in Acute Coronary Syndrome | STEMI, NSTEMI | P3 | Unknown | 4,500 | RCT, Double-blind | Ticagrelor 90mg, Ticagrelor 60mg, Aspirin |
| NCT04476173 ANalgesic Efficacy and Safety of MOrphiNe Versus Methoxyflurane in Patients With Acute Myocardial Infarction | ST Elevation Myocardial Infarction, Non ST Segment Elevation Acute Coronary Syndrome | P3 | Unknown | 200 | RCT, Open-label | Methoxyflurane - Penthrox, Morphine |
| NCT05779059 Prasugrel Or Ticagrelor De-escalation in NSTE-ACS | Non ST Segment Elevation Acute Coronary Syndrome, Non-ST-Segment Elevation Myocardial Infarction (NSTEMI) | P3 | Unknown | 50 | RCT, Open-label | De-escalation to ticagrelor 60 mg at day 30, De-escalation to prasugrel 5 mg at day 30, Switch to ticagrelor 60 mg at day 45, Switch to prasugrel 5 mg at day 45 |
| NCT07661953 Autonomic and Peripheral Neurochemical Responses to Maximal Rowing Exercise | Healhty | Completed | 15 | — | — | |
| NCT05516394 National Polish Registry of Minimally Invasive Liver Surgery | Liver Tumor | Unknown | 1,000 | — | — | |
| NCT03493256 Novel BIochemical Markers for Predicting Type 2 NEurological Complications of Surgical Coronary Revascularization (BINER) | Neurological Complication of Procedure (Disorder) | Completed | 100 | — | — | |
| NCT01332526 FFT, Inflammation, Lipid Metabolism, Blood Pressure and Organ Damage in Patients With Obesity, Chronic Kidney Disease (CKD). | Obesity, Chronic Kidney Disease | Unknown | 70 | — | — | |
| NCT03061760 Effects of Urinary Bladder Hypertrophy on Urge Urine Incontinence After Radical Prostatectomy | Prostate Cancer, Urinary Incontinence, Urge | Unknown | 250 | — | — | |
| NCT02690454 Which Platelet Function Test Best Reflects the In Vivo Plasma Concentrations of Ticagrelor and Its Active Metabolite? | Infarction, Myocardial Infarction | Completed | 45 | — | — | |
| NCT02147002 Omega-3 Acids and Cardio - Vascular Complications in Patients With Chronic Kidney Disease in Stage 1-3 | Chronic Kidney Disease, Cardiovascular Complications | N/A | Unknown | 120 | Open-label | — |
| NCT03454841 Daily Variability of Platelet Aggregation in Patients With Myocardial Infarction Treated With Prasugrel and Ticagrelor | Acute Myocardial Infarction | Completed | 73 | — | Prasugrel, Ticagrelor | |
| NCT05268640 Cervical Occlusion Double-level Stitch Application | Cervical Incompetence | N/A | Completed | 81 | RCT, Open-label | — |
| NCT07476508 "Intra-articular Hyaluronic Acid Injection for Accelerating Functional Recovery After Knee Arthroscopy" | Meniscus Lesion, Knee Injuries | N/A | Completed | 290 | RCT, Open-label | — |
| NCT05109585 Determinants of the Level of Anti-SARS-CoV-2 IgG ANTibodiEs After Vaccination Study | SARS-CoV2 Infection, SARS-CoV2 Antibodies | Unknown | 1,000 | — | — | |
| NCT02602444 Comparison of Ticagrelor Pharmacokinetics and Pharmacodynamics in STEMI and NSTEMI Patients | Myocardial Infarction | Completed | 73 | — | ticagrelor | |
| NCT03074604 Carbon Dioxide Surgical Field Flooding and Aortic No-touch Off-pump Coronary Artery Bypass Grafting to Reduce Neurological Injuries After Surgical Coronary Revascularization (CANON): a Randomised, Controlled, Investigator and Patient Blinded Single Center Superiority Trial With Three Parallel Arms. | Neurological Injury, Stroke | N/A | Completed | 192 | RCT, Double-blind | — |
| NCT05162456 Determinants of the Level of Anti-SARS-CoV-2 IgG ANTibodiEs After Vaccination Study in Patients After Organ Transplantation | SARS-CoV2 Infection, SARS-CoV2 Antibodies | Unknown | 250 | — | — | |
| NCT02611934 Mild Therapeutic Hypothermia for Patients With Acute Coronary Syndrome and Cardiac Arrest Treated With PCI | Cardiac Arrest, Acute Coronary Syndrome | N/A | Terminated | 90 | Single-blind | — |