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Cardiff Oncology, Inc.

CRDF
Healthcare|Biotechnology|US
$0.80
+0.04 (+5.30%)
DCF Value
$0.03
Tangible Book / Share
$0.39
Cash / Share
$0.50

About

Cardiff Oncology, Inc., a clinical-stage biotechnology company, develops novel therapies for the treatment of various cancers in the United States. Its lead drug candidate is Onvansertib, an oral and selective polo-like kinase 1 inhibitor for treating RAS-mutated metastatic colorectal cancer. The company also focuses on the clinical program in indications, such as investigator-initiated trials in metastatic pancreatic ductal adenocarcinoma, small cell lung cancer, metastatic triple negative breast cancer, and chronic myelomonocytic leukemia; CRDF-004, a Phase 2 open-label randomized multi-center clinical trial of onvansertib in combination with FOLFIRI and bevacizumab or FOLFOX and bevacizumab for the treatment of patients confirmed metastatic and unresectable colorectal cancer in patients with a KRAS or NRAS mutation; and TROV-054, a Phase 1b/2 single-arm clinical trial in KRAS-mutated metastatic colorectal cancer. The company was formerly known as Trovagene, Inc. and changed its name to Cardiff Oncology, Inc. in May 2012. Cardiff Oncology, Inc. was founded in 1999 and is headquartered in San Diego, California.

Stock Price

-64.7%(1Y)
1M
-25.0%
3M
-19.8%
6M
-51.5%
YTD
-71.7%
1Y
-64.3%
3Y
-27.0%
5Y
-86.0%

Pipeline Summary

14 total trials
4
Phase 1
9
Phase 2
0
Phase 3
0
Phase 4
Recruiting: 2Active: 4Completed: 6No Longer Available: 1Terminated: 1

Active Trials (6)

Targeted Pathway Inhibition in Patients With Pancreatic Cancer
NCT04005690Locally Advanced Pancreatic Ductal Adenocarcinoma
Early P1Recruiting
Enrollment: 90 participants
Onvansertib + Paclitaxel In TNBC
NCT05383196Breast Cancer
Phase 1Phase 2Active
Enrollment: 50 participants
Onvansertib in Combination With NALIRIFOX for First Line Treatment of Advanced Pancreatic Cancer
NCT06736717Pancreatic Cancer
Phase 1Phase 2Active
Enrollment: 16 participants
Study of Onvansertib in Combination With FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab Versus FOLFIRI and Bevacizumab or FOLFOX and Bevacizumab for First-Line Treatment of Metastatic Colorectal Cancer in Adult Participants With a KRAS or NRAS Mutation
NCT06106308Metastatic Colorectal Cancer
Phase 2Active
Enrollment: 110 participants
ARtificial Intelligence for Gross Tumour vOlume Segmentation
NCT05775068Lung Cancer
Active
Enrollment: 2,000 participants

Key Facts

Market Cap$61.9M
Employees30 (-6% YoY)
CEOMani Mohindru
IPO DateJul 27, 2004
Beta1.56
52-Week Range$0.7499 – $3.31
Avg Volume1,084,694
ExchangeNASDAQ

Ownership

Float93.8%
Shares Outstanding77.8M

Recent Insider Trades

Alland LeilaOTHER
Oct 23, 20260 shares
PACE GARY WBUY
Jul 14, 2026687,285 shares @ $1.46
PACE GARY WBUY
Jul 14, 2026687,285 shares @ $1.33
Mohindru ManiBUY
Jul 14, 202634,364 shares @ $1.46
Mohindru ManiBUY
Jul 14, 202634,364 shares @ $1.33

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Data last updated: Nov 9, 2026, 04:04 AM