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Heron Therapeutics, Inc.

HRTX
Healthcare|Biotechnology|US
$0.29
+0.01 (+4.64%)
Tangible Book / Share
$0.04
Cash / Share
$0.22

About

Heron Therapeutics, Inc. is a biotechnology firm dedicated to creating innovative therapies for critical patient requirements. The company leverages its proprietary Biochronomer drug delivery platform, an advanced system that enables the controlled release of various short-acting pharmacological agents. This technology ensures therapeutic concentrations are maintained for periods ranging from days to weeks following just a single administration. Among its commercialized products is SUSTOL (granisetron), an extended-release injectable designed to prevent both immediate and delayed nausea and vomiting triggered by moderately emetogenic chemotherapy, or specific anthracycline and cyclophosphamide combination therapies. Additionally, Heron markets CINVANTI, an intravenous formulation of aprepitant. CINVANTI, which acts as a substance P/neurokinin-1 receptor antagonist, is indicated for the prevention of acute and delayed chemotherapy-induced nausea and vomiting in patients undergoing highly or moderately emetogenic cancer chemotherapy. The company's development pipeline includes ZYNRELEF, an innovative dual-acting local anesthetic that combines bupivacaine, a local anesthetic, with a low dose of the nonsteroidal anti-inflammatory drug (NSAID) meloxicam in a single fixed-dose formulation. Also in development is HTX-019, an experimental therapy aimed at preventing postoperative nausea and vomiting (PONV). Furthermore, HTX-034 is being advanced for postoperative pain management and is currently undergoing Phase Ib/II clinical trials, notably in patients recovering from bunionectomy procedures. Originally established in 1983 as A.P. Pharma, Inc., the company adopted its current name, Heron Therapeutics, Inc., in January 2014. Its corporate headquarters are situated in San Diego, California.

Stock Price

-73.4%(1Y)
1M
-18.2%
3M
-40.3%
6M
-75.8%
YTD
-77.5%
1Y
-73.6%
3Y
-59.2%
5Y
-97.7%

Pipeline Summary

33 total trials
4
Phase 1
18
Phase 2
6
Phase 3
8
Phase 4
Not Yet Recruiting: 1Completed: 23Unknown: 1Recruiting: 3Withdrawn: 2Active: 2Terminated: 1

Active Trials (5)

Boron Neutron Capture Therapy With B10 L-BPA for Unresectable Recurrent Head and Neck Cancers
NCT06952868Head and Neck Cancer
Phase 2Recruiting
Enrollment: 24 participants
A Study of the Boron Neutron Capture Therapy (BNCT) Using B10 L-BPA in Malignant Brain Tumors
NCT07003139Malignant Brain Tumors
Phase 1Phase 2Recruiting
Enrollment: 10 participants
Safety Study of Repeat Doses of SUSTOL in Adults
NCT05434663Chemotherapy-Induced Nausea and Vomiting (CINV)
Phase 4Active
Enrollment: 300 participants
A Multi-surgery Assessment of ZYNRELEF (HTX-011), AMAZE. Master Protocol HTX-011-401.
NCT05109312Analgesia
Phase 4Active
Enrollment: 90 participants
A Study to Evaluate the Safety and Diagnostic Performance of F18 FBPA PET/CT Imaging in Solid Tumors
NCT07691775Solid Tumor
Phase 1Phase 2Recruiting
Enrollment: 30 participants

Key Facts

Market Cap$55.6M
Employees128 (+5% YoY)
CEOCraig Alexander Collard
IPO DateAug 26, 1987
Beta1.65
52-Week Range$0.26 – $1.58
Avg Volume2,386,965
ExchangeNASDAQ

Ownership

Float77.1%
Shares Outstanding189.9M

Recent Insider Trades

Collard Craig AOPTION EX.
Oct 31, 202634,788 shares
Collard Craig ATAX W/H
Oct 31, 20268,471 shares @ $0.28
Collard Craig AOPTION EX.
Oct 30, 202650,021 shares
Collard Craig ATAX W/H
Oct 30, 202612,181 shares @ $0.28
Collard Craig AOPTION EX.
Oct 30, 202650,021 shares

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Data last updated: Nov 9, 2026, 04:13 AM