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Inovio Pharmaceuticals, Inc.

INO
Healthcare|Biotechnology|US
$1.22
-0.23 (-16.21%)
DCF Value
$0.69
Tangible Book / Share
$0.05
Cash / Share
$0.45

About

Inovio Pharmaceuticals, Inc. is a biotechnology firm dedicated to the research, development, and market introduction of DNA-based treatments. Its core mission is to prevent and cure illnesses associated with human papillomavirus (HPV), various types of cancer, and infectious diseases. The company's advanced DNA medicine platform utilizes meticulously engineered SynCon sequences to precisely identify and optimize the genetic blueprint of a target antigen. This innovative approach is supported by its CELLECTRA smart device technology, which efficiently delivers the DNA plasmids. Inovio is actively engaged in and planning clinical trials for its DNA medicines across a wide array of conditions. These include HPV-related precancerous lesions, such as cervical, vulvar, and anal dysplasia; HPV-driven cancers affecting areas like the head and neck, cervix, anus, penis, vulva, and vagina; and other HPV-associated disorders like recurrent respiratory papillomatosis. Beyond HPV, its pipeline addresses glioblastoma multiforme, prostate cancer, and a range of infectious diseases, including HIV, Ebola, Middle East Respiratory Syndrome (MERS), and Lassa fever. The company benefits from a vast network of collaborators and partners, encompassing prominent academic institutions, government agencies, non-profit foundations, and pharmaceutical corporations. Key examples include AstraZeneca, The Bill & Melinda Gates Foundation, the Coalition for Epidemic Preparedness Innovations (CEPI), the Defense Advanced Research Projects Agency (DARPA), the National Institutes of Health, Regeneron Pharmaceuticals, and the University of Pennsylvania. Significant partnerships also involve an agreement with Richter-Helm BioLogics GmbH & Co. KG to further develop the investigational COVID-19 DNA vaccine INO-4800, alongside a strategic alliance with the International Vaccine Institute and Seoul National University Hospital. Established in 1979, Inovio Pharmaceuticals is headquartered in Plymouth Meeting, Pennsylvania.

Stock Price

-45.8%(1Y)
1M
+11.5%
3M
+81.9%
6M
-16.8%
YTD
-30.2%
1Y
-43.5%
3Y
-73.4%
5Y
-98.5%

Pipeline Summary

54 total trials
39
Phase 1
18
Phase 2
5
Phase 3
2
Phase 4
Completed: 44Terminated: 3Unknown: 2Active: 3Withdrawn: 2

Active Trials (3)

INO 5401 Vaccination in BRCA1/2 Mutation Carriers
NCT04367675BRCA1/2 Mutation
Phase 1Active
Enrollment: 44 participants
INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With Cemiplimab (REGN2810) in Newly-Diagnosed Glioblastoma (GBM)
NCT03491683Glioblastoma
Phase 1Phase 2Active
Enrollment: 52 participants
DNA Vaccine Therapy in Treating Patients With Chronic Hepatitis C Virus Infection
NCT02772003Chronic Hepatitis
Phase 1Active
Enrollment: 33 participants

Key Facts

Market Cap$83.9M
Employees112 (-16% YoY)
CEOJacqueline E. Shea
IPO DateDec 8, 1998
Beta1.71
52-Week Range$0.56 – $2.72
Avg Volume8,385,875
ExchangeNASDAQ
Websiteinovio.com

Ownership

Float118.5%
Shares Outstanding69.1M

Recent Insider Trades

YARNO WENDY LAWARD
May 20, 202641,800 shares @ $1.23
YARNO WENDY LAWARD
May 20, 202634,200 shares
Shepard JayAWARD
May 20, 202641,800 shares @ $1.23
Shepard JayAWARD
May 20, 202634,200 shares
Miller Ann CalbyAWARD
May 20, 202641,800 shares @ $1.23

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Data last updated: Nov 9, 2026, 04:16 AM