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LeonaBio, Inc.

LONA
Healthcare|Biotechnology|US
$4.42
+0.07 (+1.73%)
DCF Value
$15.07
Tangible Book / Share
$7.86
Cash / Share
$11.94

About

LeonaBio, Inc. operates as a biopharmaceutical firm engaged in clinical-stage development. Its core mission revolves around crafting small molecule therapies aimed at revitalizing neurological function and arresting the advancement of neurodegenerative conditions. The company's active development portfolio encompasses ATH-1105, an experimental therapy for amyotrophic lateral sclerosis (ALS) that is currently undergoing Phase 1 clinical assessment. Similarly, ATH-1020 is also in Phase 1 trials, targeting various neurodegenerative disorders. Furthermore, LeonaBio has an array of earlier-stage compounds in preclinical research. The company, which was originally established as Athira Pharma, Inc., rebranded itself as LeonaBio, Inc. in January 2026. Founded in 2011, its corporate headquarters are situated in Bothell, Washington.

Stock Price

+10.2%(1Y)
1M
-23.2%
3M
-42.5%
6M
-56.0%
YTD
-41.7%
1Y
-3.6%
3Y
-70.6%
5Y
-97.2%

Pipeline Summary

9 total trials
4
Phase 1
4
Phase 2
3
Phase 3
0
Phase 4
Completed: 6Terminated: 2Recruiting: 1

Active Trials (1)

Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
NCT05696626Metastatic Breast Cancer
Phase 3Recruiting
Enrollment: 600 participants

Key Facts

Market Cap$17.4M
Employees19 (-27% YoY)
CEOMark J. Litton
IPO DateSep 18, 2020
Beta1.92
52-Week Range$2.21 – $11.91
Avg Volume152,249
ExchangeNASDAQ

Ownership

Float68.0%
Shares Outstanding3.9M

Recent Insider Trades

Portman David J.BUY
Oct 26, 20263,149,470 shares @ $3149.47
Portman David J.BUY
Oct 26, 20265,502,402 shares @ $0.00
PERCEPTIVE ADVISORS LLCOPTION EX.
Oct 26, 2026776,648 shares @ $0.00
PERCEPTIVE ADVISORS LLCOPTION EX.
Oct 26, 2026776,648 shares @ $0.00
Portman David J.OTHER
Oct 26, 20265,502,402 shares @ $0.00

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$15.0M
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$9.6M
FBLGFibroBiologics, Inc. Common Stock
$6.5M
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$5.3M
LNAILunai Bioworks Inc.
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Data last updated: Nov 9, 2026, 04:20 AM