
Molecular Partners AG
MOLNHealthcare|Biotechnology|CH
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$2.61
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$1.32
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$1.50
Clinical Trials (16)
| Trial | Conditions | Phase | Status | Enrollment | Design | Drug |
|---|---|---|---|---|---|---|
| NCT07278479 Study of [212Pb]Pb-DOTAM-MAM279 ([212Pb]Pb-MP0712) in Patients With Small Cell Lung Cancer and Other DLL3 Expressing Solid Tumors | Large Cell Neuroendocrine Carcinoma, Large Cell Pulmonary Neuroendocrine Carcinoma of the Lung (LCNEC) | P1P2 | Recruiting | 138 | Open-label | [212Pb]Pb-MP0712 |
| NCT07036380 MP0317 in Combination With Chemoimmunotherapy in First Line Treatment for Patients With Advanced Biliary Tract Carcinoma | Advanced Biliary Tract Carcinoma | P2 | Recruiting | 75 | RCT, Open-label | MP0317 + Gemcitabine + Cisplatine + Durvalumab, Gemcitabine + Cisplatin + Durvalumab |
| NCT05780463 MP0420 for Inpatients With COVID-19 (An ACTIV-3/TICO Treatment Trial) | COVID-19 | P3 | Completed | 485 | RCT, Double-blind | MP0420, Placebo, Remdesivir |
| NCT04828161 A Dose Finding, Efficacy and Safety Study of Ensovibep (MP0420) in Ambulatory Adult Patients With Symptomatic COVID-19 | COVID-19 | P2P3 | Terminated | 407 | RCT, Double-blind | ensovibep, Placebo |
| NCT04501978 ACTIV-3: Therapeutics for Inpatients With COVID-19 | Covid19 | P3 | Completed | 2,753 | RCT, Double-blind | LY3819253, Placebo, Remdesivir, VIR-7831, BRII-196/BRII-198, AZD7442, MP0420, PF-07304814 |
| NCT03136653 A Phase 2 Trial of MP0250 Plus Bortezomib + Dexamethasone in Patients With Multiple Myeloma | Multiple Myeloma in Relapse | P1P2 | Completed | 33 | Open-label | MP0250 plus BOR+DEX |
| NCT04834856 Viral Clearance, PK and Tolerability of Ensovibep in COVID-19 Patients | Covid19 | P2 | Completed | 12 | Open-label | ensovibep |
| NCT02194426 First-in-human Study to Investigate the Safety, Tolerability and Blood Levels of the Test Drug MP0250 in Cancer Patients | Neoplasms | P1P2 | Completed | 58 | Open-label | MP0250 |
| NCT04870164 Safety, Tolerability and PK of Ensovibep (MP0420 - a New Candidate With Potential for Treatment of COVID-19) | COVID-19 | P1 | Terminated | 53 | RCT, Double-blind | Ensovibep, Placebo |
| NCT01086761 Study of MP0112 Intravitreal Injection in Patients With Wet Age Related Macular Degeneration | Wet Age-Related Macular Degeneration | P1 | Terminated | 32 | RCT, Open-label | MP0112 |
| NCT03084926 First-in-human Study to Investigate Safety, Blood Levels and Activity of MP0274 in Cancer Patients With HER2-positive Solid Tumors | Neoplasms | P1 | Completed | 22 | Open-label | MP0274 |
| NCT01042678 Study of MP0112 Intravitreal Injection in Patients With Diabetic Macular Edema | Diabetic Macular Edema | P1 | Terminated | 18 | RCT, Open-label | MP0112 |
| NCT05098405 First-in-human Safety and Tolerability of MP0317 in Patients With Relapsed/Refractory Advanced Solid Tumors | Advanced Malignant Solid Tumor | P1 | Terminated | 46 | Open-label | MP0317, a tri-specific fibroblast activation protein (FAP) x CD40 DARPin® drug candidate (q3w regimen), MP0317, a tri-specific fibroblast activation protein (FAP) x CD40 DARPin® drug candidate (q1w regimen) |
| NCT05673057 Study of MP0533 in Patients Acute Myeloid Leukemia or Myelodysplastic Syndrome | Leukemia, Myeloid | P1 | Completed | 80 | Open-label | MP0533 (multispecific DARPin CD3 Engager Targeting CD33, CD123 and CD70) monotherapy, Part 1, MP0533 (multispecific DARPin CD3 Engager Targeting CD33, CD123 and CD70) monotherapy, Part 2-Arm A, MP0533 (multispecific DARPin CD3 Engager Targeting CD33, CD123 and CD70) + azacitidine + venetoclax, MP0533 with Obinutuzumab pretreatment, MP0533 + azacitidine + venetoclax with optional Obinutuzumab pretreatment, Arm B relapsed/refractory AML, MP0533 + azacitidine + venetoclax with optional Obinutuzumab pretreatment, Arm B in treatment naïve patients |
| NCT03418532 MP0250 DARPin® Protein Plus Osimertinib in Patients With EGFR-mutated NSCLC | EGFR-mutated NSCLC (Disorder) | P1 | Terminated | 8 | Open-label | — |
| NCT04049903 Study to Investigate the Safety, Blood Levels and Activity of MP0310 in Patients With Advanced Solid Tumors | Advanced Solid Tumor | P1 | Completed | 38 | Open-label | MP0310 |