Intellia Therapeutics Inc
NTLAHealthcare|Biotechnology|USA
$14.21
-1.23 (-7.99%)
Tangible Book
$5.16
Clinical Trials (10)
| Trial | Conditions | Phase | Status | Enrollment | Design | Drug |
|---|---|---|---|---|---|---|
| NCT06634420 HAELO: A Phase 3 Study to Evaluate NTLA-2002 in Participants With Hereditary Angioedema (HAE) | Hereditary Angioedema | P3 | Active | 80 | RCT, Double-blind | NTLA-2002, Normal Saline IV Administration |
| NCT06128629 MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM) | Transthyretin Amyloidosis (ATTR) With Cardiomyopathy | P3 | Recruiting | 1,200 | RCT, Double-blind | NTLA-2001, Placebo |
| NCT06672237 A Phase 3 Study of NTLA-2001 in ATTRv-PN | Neuromuscular Disease, Neuromuscular Diseases (NMD) | P3 | Recruiting | 60 | RCT, Double-blind | nexiguran ziclumeran, Normal Saline as Placebo |
| NCT06379789 A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B | Hemophilia B | P1P2 | Recruiting | 130 | Open-label | REGV131, LNP1265 |
| NCT05120830 NTLA-2002 in Adults With Hereditary Angioedema (HAE) | Hereditary Angioedema | P1P2 | Active | 37 | RCT, Double-blind | Biological NTLA-2002 |
| NCT05697861 Long-Term Follow-Up (LTFU) of Subjects Dosed With NTLA-2001 | Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy, Transthyretin-Related (ATTR) Familial Amyloid Cardiomyopathy | Recruiting | 72 | — | — | |
| NCT06622668 NTLA-3001 in Adults with Alpha-1 Antitrypsin Deficiency-Associated Lung Disease | Lung Disease, Pulmonary Disease | P1P2 | Withdrawn | — | Open-label | Biological NTLA-3001 |
| NCT05066165 Study Investigating NTLA-5001 in Subjects With Acute Myeloid Leukemia | Acute Myeloid Leukemia | P1P2 | Terminated | 6 | Open-label | — |
| NCT04601051 Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of NTLA-2001 in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy (ATTRv-PN) and Patients With Transthyretin Amyloidosis-Related Cardiomyopathy (ATTR-CM) | Transthyretin-Related (ATTR) Familial Amyloid Polyneuropathy, Transthyretin-Related (ATTR) Familial Amyloid Cardiomyopathy | P1 | Completed | 72 | Open-label | NTLA-2001 |
| NCT06262399 Long-Term Follow-Up (LTFU) of Subjects Treated With NTLA 2002 | Hereditary Angioedema | By Invite | 100 | — | — |