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OnKure Therapeutics, Inc.

OKUR
Healthcare|Biotechnology|US
$2.87
+0.34 (+13.47%)
DCF Value
$4.23
Tangible Book / Share
$3.16
Cash / Share
$3.27

About

OnKure, Inc., established in 2011 and based in Boulder, Colorado, operates as a biopharmaceutical company primarily engaged in the creation and advancement of precise therapeutic agents for cancer. A core area of their research centers on developing highly selective inhibitors for histone deacetylases. Their current pipeline features OKI-179, an inhibitor specifically engineered to combat a wide spectrum of malignancies, including both blood-related cancers and solid tumor formations.

Stock Price

-9.2%(1Y)
1M
+24.6%
3M
-30.8%
6M
-26.7%
YTD
-1.2%
1Y
-6.7%
3Y
-95.9%
5Y
-96.6%

Pipeline Summary

9 total trials
6
Phase 1
3
Phase 2
1
Phase 3
0
Phase 4
Completed: 6Active: 1Terminated: 2

Active Trials (1)

First-in-Human Study of OKI-219 in Advanced Solid Tumors and Advanced Breast Cancer
NCT06239467Advanced Cancer
Phase 1Active
Enrollment: 200 participants

Key Facts

Market Cap$116.0M
Employees45 (-2% YoY)
CEONicholas A. Saccomano
IPO DateApr 8, 2021
Beta0.30
52-Week Range$2.01 – $5.38
Avg Volume253,694
ExchangeNASDAQ

Ownership

Float68.7%
Shares Outstanding40.5M

Recent Insider Trades

Saccomano Nicholas ASELL
Sep 21, 202687 shares @ $2.97
Leverone Jason A.SELL
Sep 21, 2026302 shares @ $2.97
Manke IsaacOTHER
Aug 7, 20260 shares
Mathers Edward TAWARD
Aug 7, 202622,350 shares @ $4.14
Ratcliffe LiamAWARD
Aug 7, 202622,350 shares @ $4.14

Peers

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$45.0M
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$30.2M
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$25.5M
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$36.7M
KZRKezar Life Sciences, Inc.
$53.9M
MRSNMersana Therapeutics, Inc.
$145.4M
PDSBPDS Biotechnology Corporation
$68.7M
Data last updated: Nov 9, 2026, 04:26 AM