PMVP logo

PMV Pharmaceuticals, Inc.

PMVP
Healthcare|Biotechnology|US
$1.26
-0.01 (-1.18%)
DCF Value
$0.65
Tangible Book / Share
$1.34
Cash / Share
$1.49

About

PMV Pharmaceuticals, Inc. operates as a precision oncology company focused on discovering and developing both small molecule and tumor-agnostic therapies to address p53 mutations in cancer patients. Their leading experimental drug, PC14586, is a small molecule designed to correct the p53 protein specifically when it contains the Y220C mutation, thereby restoring its natural, functional state. The company is also progressing a pipeline of other programs targeting various mutant p53 forms, including Wild-type p53 Induced-Phosphatase, R282W, R273H, and other prevalent p53 hotspot mutations. Originally known as PJ Pharmaceuticals, Inc., the firm rebranded to PMV Pharmaceuticals, Inc. in July 2013. The company was founded in 2013 and has its main operational base in Cranbury, New Jersey.

Stock Price

+0.8%(1Y)
1M
-15.4%
3M
+5.9%
6M
-10.6%
YTD
+0.8%
1Y
-3.1%
3Y
-32.3%
5Y
-94.9%

Pipeline Summary

7 total trials
7
Phase 1
1
Phase 2
0
Phase 3
0
Phase 4
Recruiting: 3Completed: 4

Active Trials (3)

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
NCT04585750Advanced Solid Tumor
Phase 1Phase 2Recruiting
Enrollment: 300 participants
A Phase Ib Study of Rezatapopt in Combination With Azacitidine in Patients With TP53Y220C Mutant Myeloid Malignancies (Acute Myeloid Leukemia or Myelodysplastic Syndrome)
NCT06616636Myelodysplastic Syndrome
Phase 1Recruiting
Enrollment: 24 participants
A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation.
NCT07372625TP53 Y220C Mutation
Phase 1Recruiting
Enrollment: 14 participants

Key Facts

Market Cap$67.2M
Employees54 (+15% YoY)
CEODavid H. Mack
IPO DateSep 25, 2020
Beta1.35
52-Week Range$1.02 – $1.91
Avg Volume582,374
ExchangeNASDAQ

Ownership

Float91.7%
Shares Outstanding53.3M

Recent Insider Trades

Eckler Matthew JosephAWARD
Oct 1, 202684,000 shares @ $1.75
Eckler Matthew JosephOTHER
Oct 1, 20260 shares
Stelzer LaurieAWARD
Jun 4, 202642,000 shares @ $1.19
LEVINE ARNOLD JAWARD
Jun 4, 202642,000 shares @ $1.19
Gallagher Carol GiltnerAWARD
Jun 4, 202642,000 shares @ $1.19

Peers

ACRVAcrivon Therapeutics, Inc. Common Stock
$69.0M
ATYRaTyr Pharma, Inc.
$15.6M
BMEABiomea Fusion, Inc.
$41.0M
CBUSCibus, Inc.
$90.2M
IMUXImmunic, Inc.
$105.7M
LITSLite Strategy, Inc.
$31.0M
RLMDRelmada Therapeutics, Inc.
$416.0M
RPTXRepare Therapeutics Inc.
$114.2M
Data last updated: Nov 9, 2026, 04:29 AM