PYXS logo

Pyxis Oncology, Inc.

PYXS
Healthcare|Biotechnology|US
$1.66
+0.05 (+3.11%)
DCF Value
$1.70
Tangible Book / Share
$0.49
Cash / Share
$0.67

Analyst Consensus

Buy12 analysts
Strong Buy
0
Buy
10
Hold
2
Sell
0
Strong Sell
0
Consensus Target
$7.00
Implied Upside
+321.7%
Low Target
$5.00
High Target
$8.00

Price Target Trend

Last Month
$5.00
1 target · +201% vs price
Last Quarter
$7.00
3 targets · +322% vs price
Last Year
$6.71
7 targets · +304% vs price
All Time
$7.17
12 targets · +332% vs price

Rating Trend

Dec 25
8 buy · 1 hold · 0 sell
Jan 26
8 buy · 1 hold · 0 sell
Feb 26
8 buy · 1 hold · 0 sell
Mar 26
8 buy · 1 hold · 0 sell
Apr 26
8 buy · 1 hold · 0 sell
May 26
9 buy · 1 hold · 0 sell
Jun 26
9 buy · 1 hold · 0 sell
Jul 26
8 buy · 1 hold · 0 sell
Aug 26
9 buy · 1 hold · 0 sell
Sep 26
9 buy · 1 hold · 0 sell
Oct 26
9 buy · 1 hold · 0 sell
Nov 26
9 buy · 1 hold · 0 sell

Recent Price Targets

DateFirmAnalystTargetPrice ThenSource
Nov 5, 2026Stifel NicolausBradley Canino$5.00(+211%)$1.61StreetInsider
Sep 10, 2026H.C. WainwrightSwayampakula Ramakanth$8.00(+137%)$3.38TheFly
Sep 10, 2026WedbushRobert Driscoll$8.00(+137%)$3.38StreetInsider
Jul 2, 2026Leerink PartnersJeffrey La Rosa$7.00(+146%)$2.85StreetInsider
May 5, 2026WedbushRobert Driscoll$6.00(+241%)$1.76TheFly
Dec 18, 2025RBC CapitalLeonid Timashev$5.00(+189%)$1.73StreetInsider
Nov 24, 2025StephensSudan Loganathan$8.00(+67%)$4.80TheFly
Nov 4, 2025GuggenheimBradley Canino$7.00(+84%)$3.81StreetInsider
Sep 4, 2025Guggenheim$5.00(+211%)$1.61TheFly
Aug 16, 2024H.C. WainwrightSwayampakula Ramakanth$7.00(+99%)$3.52StreetInsider
Aug 7, 2024Stifel NicolausBradley Canino$10.00(+219%)$3.13TheFly
May 7, 2024JefferiesFarzin Haque$10.00(+132%)$4.31StreetInsider

Recent Rating Actions

FirmActionRatingDate
WedbushmaintainOutperformNov 6, 2026
RBC CapitalmaintainOutperformNov 6, 2026
WedbushmaintainOutperformSep 10, 2026
HC Wainwright & Co.maintainBuySep 10, 2026
Wells FargomaintainOverweightSep 9, 2026
HC Wainwright & Co.maintainBuyAug 18, 2026
Leerink PartnersmaintainOutperformJul 2, 2026
HC Wainwright & Co.maintainBuyMar 24, 2026
StifelmaintainBuyMar 24, 2026
RBC CapitalmaintainOutperformDec 19, 2025
HC Wainwright & Co.maintainBuyDec 19, 2025
Stephens & Co.maintainOverweightNov 24, 2025
GuggenheimmaintainBuyNov 4, 2025
HC Wainwright & Co.maintainBuyAug 19, 2025
HC Wainwright & Co.maintainBuyMay 19, 2025
RBC CapitalmaintainOutperformMar 19, 2025
HC Wainwright & Co.maintainBuyMar 19, 2025
HC Wainwright & Co.maintainBuyDec 20, 2024
RBC CapitalmaintainOutperformDec 20, 2024
William BlairdowngradeOutperform →Market PerformNov 21, 2024
HC Wainwright & Co.maintainBuyNov 21, 2024
RBC CapitalmaintainOutperformNov 21, 2024
RBC CapitalmaintainOutperformSep 19, 2024
HC Wainwright & Co.maintainBuyAug 16, 2024
HC Wainwright & Co.maintainBuyMay 16, 2024

Earnings History

Next report: Mar 22, 2027 · EPS est. $-0.26
Report DateEPS ActualEPS Est.Revenue ActualRevenue Est.
Nov 5, 2026$-0.24$-0.27——
Aug 13, 2026$-0.40$-0.35—$33.3K
May 14, 2026$-0.37$-0.35—$19.4K
Mar 23, 2026$-0.29$-0.35$11.0M$125.0K
Nov 3, 2025$-0.35$-0.36——
Aug 14, 2025$-0.30$-0.36$2.8M—
May 15, 2025$-0.35$-0.29——
Mar 18, 2025$-0.58$-0.33—$100.0K

News

Pyxis Oncology Reports Third Quarter 2026 Financial Results and Highlights Progress Toward Pivotal Development of Micvotabart Pelidotin (MICVO)

Updated Phase 1 monotherapy results in second-line and beyond recurrent/metastatic head and neck squamous cell carcinoma (2L+ R/M HNSCC) showed compelling efficacy data with a manageable safety profile FDA feedback on dose selection from the End-of-Phase 2 meeting expected in the first quarter of 2027; global Phase 3 Headliner SM trial initiation planned for mid-2027 Updated overall survival data from the MICVO Phase 1 monotherapy study expected in the first half of 2027 MICVO Phase 1 monotherap…

Nov 5, 2026globenewswire.com
Pyxis Oncology to Participate in Upcoming Investor Conferences

BOSTON, Oct. 28, 2026 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: PYXS), a clinical-stage company developing next-generation therapeutics for difficult-to-treat cancers, today announced that Tom Civik, Chief Executive Officer and Chairman of Pyxis Oncology, will participate in fireside chats at two upcoming conferences.

Oct 28, 2026globenewswire.com
Pyxis Oncology to Present Micvotabart Pelidotin (MICVO) Phase 1 Monotherapy Data in Late-Breaking Oral Presentation and Two Poster Presentations at EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics

BOSTON, Oct. 27, 2026 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: PYXS), a clinical-stage company developing next-generation therapeutics for difficult-to-treat cancers, today announced a late-breaking oral presentation on micvotabart pelidotin (MICVO) monotherapy in previously treated recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) at the 38th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, to take place in Barcelona, Spain, November 18 - No…

Oct 27, 2026globenewswire.com
Pyxis Oncology (NASDAQ:PYXS) & Precigen (NASDAQ:PGEN) Head to Head Analysis

Precigen (NASDAQ: PGEN - Get Free Report) and Pyxis Oncology (NASDAQ: PYXS - Get Free Report) are both healthcare companies, but which is the better investment? We will compare the two companies based on the strength of their analyst recommendations, valuation, profitability, dividends, earnings, institutional ownership and risk. Institutional and Insider Ownership 33.5% of Precigen shares are

Oct 10, 2026defenseworld.net
Pyxis Oncology: Better Runway Is Bullish For MICVO's Remaining R&D

PYXS's main value driver is MICVO. This is an oncology drug candidate that could be useful for killing cancerous cells. MICVO's early data has been promising, but PYXS still has to find an adequate dose that's safe and effective. Fortunately, PYXS's recent raise helps their financing in the near term and should be enough for them to reach important clinical milestones with MICVO.

Oct 4, 2026seekingalpha.com
Pyxis Oncology Announces Closing of Up to $282.6 Million Public Offering

BOSTON, Oct. 02, 2026 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: PYXS or the “Company”), a clinical-stage company developing next-generation therapeutics for difficult-to-treat cancers, today announced that it closed its previously announced registered public offering (the "Offering") on October 1, 2026. The Offering generated approximately $110.0 million in upfront gross proceeds, before deducting underwriting discounts and commissions and other offering expenses. The Offering consisted …

Oct 2, 2026globenewswire.com
Critical Survey: Pyxis Oncology (NASDAQ:PYXS) versus Inovio Pharmaceuticals (NASDAQ:INO)

Pyxis Oncology (NASDAQ: PYXS - Get Free Report) and Inovio Pharmaceuticals (NASDAQ: INO - Get Free Report) are both small-cap healthcare companies, but which is the better stock? We will compare the two businesses based on the strength of their analyst recommendations, dividends, institutional ownership, earnings, profitability, risk and valuation. Earnings and Valuation This table compares Pyxis

Oct 1, 2026defenseworld.net
Pyxis Oncology Announces Pricing of Up to $282.6 Million Public Offering

BOSTON, Sept. 30, 2026 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: PYXS), a clinical-stage company developing next-generation therapeutics for difficult-to-treat cancers, today announced the pricing of its previously announced registered public offering (the "Offering") of 36,047,919 shares of its common stock, or in lieu of common stock to certain investors, 1,883,121 pre-funded warrants to purchase shares of common stock, and accompanying common warrants to purchase 49,310,352 shares of …

Sep 30, 2026globenewswire.com
Pyxis Oncology Announces Proposed Public Offering

BOSTON, Sept. 29, 2026 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: PYXS), a clinical-stage company developing next-generation therapeutics for difficult-to-treat cancers, today announced that it has commenced a registered public offering (the "Offering") of (i) shares of its common stock, or in lieu of common stock to certain investors, pre-funded warrants to purchase shares of common stock, and (ii) accompanying common warrants to purchase shares of common stock. Each share of common stoc…

Sep 29, 2026globenewswire.com
Critical Analysis: Pyxis Oncology (NASDAQ:PYXS) vs. ProKidney (NASDAQ:PROK)

ProKidney (NASDAQ: PROK - Get Free Report) and Pyxis Oncology (NASDAQ: PYXS - Get Free Report) are both small-cap healthcare companies, but which is the better stock? We will compare the two businesses based on the strength of their dividends, analyst recommendations, valuation, earnings, risk, institutional ownership and profitability. Analyst Recommendations This is a breakdown of recent

Sep 21, 2026defenseworld.net
Alumis (NASDAQ:ALMS) & Pyxis Oncology (NASDAQ:PYXS) Head-To-Head Review

Pyxis Oncology (NASDAQ: PYXS - Get Free Report) and Alumis (NASDAQ: ALMS - Get Free Report) are both small-cap healthcare companies, but which is the superior investment? We will compare the two businesses based on the strength of their analyst recommendations, dividends, profitability, valuation, earnings, institutional ownership and risk. Valuation and Earnings This table compares Pyxis Oncology

Sep 16, 2026defenseworld.net
Pyxis Oncology, Inc. (PYXS) Discusses MICVO Monotherapy Phase I Clinical Data in Head and Neck Squamous Cell Carcinoma Transcript

Pyxis Oncology, Inc. (PYXS) Discusses MICVO Monotherapy Phase I Clinical Data in Head and Neck Squamous Cell Carcinoma Transcript

Sep 10, 2026seekingalpha.com
Pyxis Oncology Analyst Flags Key Safety Liabilities from Cancer Drug

Pyxis Oncology Inc. (NASDAQ:PYXS) on Wednesday shared updated data from its Phase 1 trial evaluating micvotabart pelidotin (MICVO).

Sep 9, 2026benzinga.com
Pyxis Oncology Announces Positive Updated Data from Phase 1 Monotherapy Study of Micvotabart Pelidotin (MICVO) in Second-Line and Beyond Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (2L+ R/M HNSCC)

MICVO demonstrated rapid and deep responses, with a 36% confirmed objective response rate (cORR) and 94% disease control rate (DCR), with clinical activity observed across HPV status and prior-treatment subgroups Substantial survival outcomes include median progression-free survival (mPFS) of 6.2 months and 12-month overall survival (OS) probability of 79%, with clinical activity observed across HPV status and prior-treatment subgroups No new safety signals observed; tolerability profile expecte…

Sep 9, 2026globenewswire.com
Pyxis Oncology to Host Webcast to Present Updated Data from Phase 1 Monotherapy Study of Micvotabart Pelidotin (MICVO) in Second-Line and Beyond Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (2L+ R/M HNSCC)

BOSTON, Sept. 08, 2026 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: PYXS), a clinical-stage company developing next-generation therapeutics for difficult-to-treat cancers, today announced that it will host a live webcast on September 9, 2026 at 7:30 a.m.

Sep 8, 2026globenewswire.com
Pyxis Oncology Appoints Thomas Civik Chief Executive Officer and Chairman of the Board

John Flavin, Co-Founder and Founding Chairman, to serve as Lead Independent Director of the Board Leadership transition reflects continued focus on advancing MICVO through key clinical milestones BOSTON, Sept. 08, 2026 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: PYXS), a clinical-stage company developing next-generation therapeutics for difficult-to-treat cancers, announced today that its Board of Directors has appointed Thomas Civik as Chief Executive Officer and Chairman of the Board, ef…

Sep 8, 2026globenewswire.com
Pyxis Oncology to Participate in Upcoming Investor Conferences

BOSTON, Sept. 01, 2026 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: PYXS), a clinical-stage company developing next-generation therapeutics for difficult-to-treat cancers, today announced that Tom Civik, Interim Chief Executive Officer and Director of Pyxis Oncology, will participate in fireside chats at three upcoming conferences.

Sep 1, 2026globenewswire.com
Pyxis Oncology Reports Second Quarter 2026 Financial Results and Advances MICVO Toward Key 2026 Clinical Milestones

Updated data from the MICVO Phase 1 monotherapy study in 2L+ R/M HNSCC on track to be reported in Fall 2026; update to include detailed analyses of patients treated at or below a dose cap Updated data from the MICVO Phase 1/2 combination study with pembrolizumab in 1L R/M HNSCC on track to be reported in the fourth quarter of 2026 Completed private placement financing for up to $114 million, providing approximately $50 million in upfront gross proceeds to support additional patient follow-up Upf…

Aug 13, 2026globenewswire.com
Financial Analysis: Pyxis Oncology (NASDAQ:PYXS) and GenSight Biologics (OTCMKTS:GSGTF)

GenSight Biologics (OTCMKTS:GSGTF - Get Free Report) and Pyxis Oncology (NASDAQ: PYXS - Get Free Report) are both healthcare companies, but which is the superior investment? We will compare the two businesses based on the strength of their profitability, valuation, risk, earnings, analyst recommendations, dividends and institutional ownership. Insider and Institutional Ownership 39.1% of Pyxis Oncology

Aug 13, 2026defenseworld.net