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Cartesian Therapeutics, Inc.

RNAC
Healthcare|Biotechnology|US
$7.53
+0.75 (+11.06%)
DCF Value
$3.97
Cash / Share
$4.06

About

Cartesian Therapeutics, Inc., a clinical-stage biotechnology company, provides mRNA cell therapies for the treatment of autoimmune diseases. The company’s lead product candidate is Descartes-08, an autologous mRNA chimeric antigen receptor T-cell cell therapy (CAR-T) directed against the B cell maturation antigen (BCMA), which is in Phase 2b clinical trials for the treatment of autoimmune diseases, generalized myasthenia gravis, and systemic lupus erythematosus, as well as rare pediatric disease designation for the treatment of juvenile dermatomyositis. It is also developing Descartes-15, which is in phase 1 trials, an autologous autologous B cell maturation antigen (BCMA) directed mRNA CAR-T to treat patients with multiple myeloma. The company is headquartered in Frederick, Maryland.

Stock Price

-0.3%(1Y)
1M
+10.4%
3M
-14.9%
6M
-12.9%
YTD
+4.4%
1Y
+4.0%
3Y
-76.1%
5Y
-93.7%

Pipeline Summary

12 total trials
6
Phase 1
6
Phase 2
1
Phase 3
0
Phase 4
Active: 3Terminated: 6Recruiting: 2Completed: 1

Active Trials (5)

Descartes-08 for Patients With Systemic Lupus Erythematosus
NCT06038474Systemic Lupus Erythematosus (SLE)
Phase 2Active
Enrollment: 6 participants
Investigating an mRNA CAR T-cell Therapy, Known as Descartes-08, as a Potential Approach to Treat Myasthenia Gravis
NCT06799247Myasthaenia Gravis
Phase 3Active
Enrollment: 128 participants
Descartes-08 in Autoantibody Myositis
NCT07391605Antisynthetase Syndrome
Phase 2Recruiting
Enrollment: 60 participants
Descartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG)
NCT04146051Myasthenia Gravis, Generalized
Phase 2Active
Enrollment: 30 participants
Descartes-08 for Children, Adolescents, and Young Adults With Autoimmune Disorders
NCT07089121Childhood-onset Systemic Lupus Erythematous
Phase 1Phase 2Recruiting
Enrollment: 50 participants

Key Facts

Market Cap$227.8M
Employees75 (+14% YoY)
CEOCarsten Brunn
IPO DateJun 22, 2016
Beta0.62
52-Week Range$5.6 – $11
Avg Volume131,898
ExchangeNASDAQ

Ownership

Float38.3%
Shares Outstanding30.3M

Recent Insider Trades

Hoge ElizabethOPTION EX.
Apr 2, 2026758,001 shares
Hoge ElizabethOPTION EX.
Apr 2, 202622,740.03 shares
Kalayoglu MuratOPTION EX.
Apr 2, 2026758,001 shares
Kalayoglu MuratOPTION EX.
Apr 2, 202622,740.03 shares
Singer MichaelGIFT
Mar 13, 20266,555 shares

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Data last updated: Nov 9, 2026, 04:32 AM