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Sagimet Biosciences Inc.

SGMT
Healthcare|Biotechnology|US
$9.85
+0.73 (+8.00%)
DCF Value
$1.05
Tangible Book / Share
$4.82
Cash / Share
$4.52

About

Sagimet Biosciences Inc., a clinical-stage biopharmaceutical company, develops novel therapeutics called fatty acid synthase (FASN) inhibitors for the treatment of diseases that result from dysfunctional metabolic and fibrotic pathways in the United States. The company’s lead drug candidate is Denifanstat, an oral, once-daily pill and selective FASN inhibitor for the treatment of metabolic dysfunction-associated steatohepatitis, acne, and select forms of cancer. It also develops TVB-3567, a FASN inhibitor for the treatment of acne indication; and other oncology programs, such as solid tumor and glioblastoma. The company was formerly known as 3-V Biosciences, Inc. and changed its name to Sagimet Biosciences Inc. in August 2019. Sagimet Biosciences Inc. was incorporated in 2006 and is headquartered in San Mateo, California.

Stock Price

+28.1%(1Y)
1M
+10.4%
3M
+8.7%
6M
+27.8%
YTD
+66.4%
1Y
+18.2%
3Y
+180.6%
5Y
-38.2%

Pipeline Summary

13 total trials
7
Phase 1
4
Phase 2
3
Phase 3
0
Phase 4
Recruiting: 2Completed: 7Withdrawn: 2Active: 2

Active Trials (4)

Phase 1 Study to Evaluate the Safety, Tolerability, PK, and PD of TVB-3567 in Healthy Participants With or Without Acne
NCT06989840Acne
Phase 1Recruiting
Enrollment: 152 participants
Phase 3 Study of Denifanstat in Participants With Moderate to Severe Acne (AURORA)
NCT07863193Acne Vulgaris
Phase 3Recruiting
Enrollment: 800 participants
Study of TVB-2640 in Men With Metastatic Castration-Resistant Prostate Cancer
NCT05743621Prostatic Neoplasms, Castration-Resistant
Phase 1Active
Enrollment: 8 participants
Phase 2 Study of TVB-2640 in KRAS Non-Small Cell Lung Carcinomas
NCT03808558KRAS Gene Mutation
Phase 2Active
Enrollment: 18 participants

Key Facts

Market Cap$320.9M
Employees16 (+14% YoY)
CEODavid Happel
IPO DateJul 14, 2023
Beta3.47
52-Week Range$4.5 – $11.45
Avg Volume1,213,129
ExchangeNASDAQ

Ownership

Float95.8%
Shares Outstanding32.6M

Recent Insider Trades

Kemble GeorgeOPTION EX.
Aug 14, 202624,369 shares @ $6.36
Kemble GeorgeOPTION EX.
Aug 14, 2026326,618 shares @ $6.36
Kemble GeorgeSELL
Aug 14, 2026350,987 shares @ $10.23
Kemble GeorgeOPTION EX.
Aug 14, 2026326,618 shares @ $6.36
Kemble GeorgeOPTION EX.
Aug 14, 202624,369 shares @ $6.36

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Data last updated: Nov 9, 2026, 04:33 AM