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Tiziana Life Sciences Ltd

TLSA
Healthcare|Biotechnology|GB
$0.69
+0.07 (+11.03%)
DCF Value
$0.01
Cash / Share
$0.02

About

Tiziana Life Sciences Ltd is a biotechnology firm dedicated to the research and advancement of novel molecular therapies for human ailments, particularly within oncology and immunology. Its flagship immunology program features Foralumab (TZLS-401), a human anti-CD3 monoclonal antibody under development for a range of conditions including Crohn's disease, graft versus host disease, ulcerative colitis, multiple sclerosis, type-1 diabetes, inflammatory bowel disease, psoriasis, and rheumatoid arthritis. Additionally, the company is progressing Milciclib (TZLS-201), a small molecule inhibitor that targets multiple cyclin-dependent, tropomycin receptor, and Src family kinases to suppress abnormal cell growth and cancer progression. Another significant asset is anti-Interleukin 6 receptor (IL6R) mAb (TZLS-501), a fully human monoclonal antibody intended to mitigate IL6-induced inflammation and treat COVID-19 patients. Founded in 1998, Tiziana Life Sciences is based in London, United Kingdom.

Stock Price

-61.7%(1Y)
1M
-39.0%
3M
-31.1%
6M
-56.4%
YTD
-53.8%
1Y
-60.6%
3Y
+9.6%
5Y
-54.1%

Pipeline Summary

15 total trials
3
Phase 1
11
Phase 2
0
Phase 3
0
Phase 4
Withdrawn: 4Recruiting: 3Active: 1Terminated: 2Available: 1Unknown: 1By Invitation: 1Completed: 2

Active Trials (4)

Nasal Foralumab in Patients With Non-Active Secondary Progressive Multiple Sclerosis
NCT06890923Non-Active Secondary Progressive Multiple Sclerosis
Phase 2Recruiting
Enrollment: 55 participants
A Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis Patients
NCT06292923Secondary Progressive Multiple Sclerosis
Phase 2Active
Enrollment: 54 participants
Assessment of Foralumab Safety and Modulation of Microglial Activation in Alzheimer's Disease
NCT06489548Dementia
Phase 2Recruiting
Enrollment: 16 participants
A Phase 2a Study of Foralumab Nasal in Patients With Multiple System Atrophy (MSA)
NCT06868628Multiple System Atrophy
Phase 2Recruiting
Enrollment: 5 participants

Key Facts

Market Cap$87.7M
Employees10
CEOIvor R. Elrifi
IPO DateNov 20, 2018
Beta0.46
52-Week Range$0.5671 – $2.6
Avg Volume677,261
ExchangeNASDAQ

Ownership

Float50.4%
Shares Outstanding127.3M

Recent Insider Trades

Elrifi IvorOPTION EX.
Aug 15, 20261,050,000 shares
Elrifi IvorOPTION EX.
Aug 15, 20261,050,000 shares
CERRONE GABRIELE MBUY
Jul 21, 202642,357 shares @ $0.99
CERRONE GABRIELE MBUY
Jun 12, 202615,000 shares @ $1.11
Elrifi IvorBUY
Aug 5, 2026237,616 shares @ $1.00

Peers

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$11.2M
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$70.1M
ESLAEstrella Immunopharma, Inc.
$16.3M
EXOZeXoZymes, Inc.
$40.8M
IMMXImmix Biopharma, Inc.
$668.2M
MGNXMacroGenics, Inc.
$148.4M
OKYOOKYO Pharma Limited
$75.0M
PLRXPliant Therapeutics, Inc.
$50.1M
Data last updated: Nov 9, 2026, 04:37 AM