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WAVE Life Sciences Ltd

WVE
Healthcare|Biotechnology|Singapore
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Clinical Trials (15)

TrialConditionsPhaseStatusEnrollmentDesignDrug
NCT04906460
Open-label Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy (FORWARD-53)
Duchenne Muscular Dystrophy
P1P2
Recruiting26Open-labelWVE-N531
NCT06842186
A Phase 1/2a Study of WVE-007 in Adults Living With Overweight or Obesity
Overweight and Obesity
P1P2
Recruiting296RCT, Double-blindWVE-007
NCT06405633
A Phase 1b/2a, Open-label Single Ascending Doses and Multiple Ascending Doses Study in Participants With Pi*ZZ AATD
Alpha-1 Antitrypsin Deficiency
P1P2
Active24Open-labelWVE-006
NCT03907072
Efficacy and Safety Study of WVE-210201 (Suvodirsen) With Open-label Extension in Ambulatory Patients With Duchenne Muscular Dystrophy
Duchenne Muscular Dystrophy
P2P3
Terminated6RCT, Double-blindWVE-210201 (suvodirsen), Placebo
NCT03225846
Safety and Tolerability of WVE-120102 in Patients With Huntington's Disease
Huntington's Disease
P1P2
Terminated88RCT, Double-blindWVE-120102, Placebo
NCT07209332
Open-Label Extension Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy
Duchenne Muscular Dystrophy
P2
By Invite175Open-labelWVE-N531
NCT04617847
Open-label Extension Study to Evaluate the Safety and Tolerability of WVE-120101 in Patients With Huntington's Disease
Huntington Disease
P1P2
Terminated27Open-labelWVE-120101
NCT03225833
Safety and Tolerability of WVE-120101 in Patients With Huntington's Disease
Huntington's Disease
P1P2
Terminated61RCT, Double-blindWVE-120101, Placebo
NCT05032196
Study of WVE-003 in Patients With Huntington's Disease
Huntington Disease
P1P2
Completed47RCT, Double-blindSAD: 30mg WVE-003, SAD: 60mg WVE-003, SAD: 90mg WVE-003, SAD: Pooled Placebo, MD: 30mg WVE-003, MD: Placebo
NCT04617860
Open-label Extension Study to Evaluate the Safety and Tolerability of WVE-120102 in Patients With Huntington's Disease
Huntington Disease
P1P2
Terminated36Open-labelWVE-120102
NCT05683860
Open-label Extension (OLE) Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) and/or Frontotemporal Dementia (FTD)
ALS, FTD
P1P2
Terminated8Open-labelWVE-004
NCT04931862
Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) or Frontotemporal Dementia (FTD)
ALS, FTD
P1P2
Terminated35RCT, Double-blindWVE-004, Placebo
NCT06186492
A Phase 1 Research Study to Evaluate Safety, Tolerability, and Pharmacokinetics of WVE-006 in Healthy Participants With Wild-type AAT Expression (RestorAATion-1)
Alpha-1 Antitrypsin Deficiency (AATD)
P1
Completed47RCT, Double-blindWVE-006
NCT03508947
Safety and Tolerability of WVE-210201 in Patients With Duchenne Muscular Dystrophy
Duchenne Muscular Dystrophy
P1
Completed36RCT, Double-blindWVE-210201, Placebo
NCT03680365
Your Voice; Impact of Duchenne Muscular Dystrophy (DMD) on the Lives of Families
Duchenne Muscular Dystrophy, Burden, Dependency
Completed60