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Clene Inc.

CLNN
Healthcare|Biotechnology|US
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Clinical Trials (13)

TrialConditionsPhaseStatusEnrollmentDesignDrug
NCT05299658
An Open-Label Extension for the Phase 2 Study in Early Symptomatic Amyotrophic Lateral Sclerosis Patients on Stable Background Therapy to Assess Bioenergetic Catalysis With CNM-Au8 to Slow Disease Progression in ALS
Amyotrophic Lateral Sclerosis
P2
Active40Open-labelCNMAu8
NCT04626921
A Multi-Center, Open-Label Long-Term Extension Study of CNM-Au8 In Patients With Stable Relapsing Multiple Sclerosis
Relapsing Multiple Sclerosis
P2P3
Completed55Open-labelCNM-Au8
NCT04414345
HEALEY ALS Platform Trial - Regimen C CNM-Au8
Amyotrophic Lateral Sclerosis
P2P3
Completed161RCT, Double-blindCNM-Au8, Matching Placebo
NCT03536559
Nanocrystalline Gold to Treat Remyelination Failure in Chronic Optic Neuropathy In Multiple Sclerosis
Relapsing Remitting Multiple Sclerosis, Optic Neuropathy
P2
Terminated73RCT, Double-blindCNM-Au8, Placebo
NCT04098406
Therapeutic Nanocatalysis to Slow Disease Progression of Amyotrophic Lateral Sclerosis (ALS)
Amyotrophic Lateral Sclerosis
P2
Completed45RCT, Double-blindCNM-Au8, Placebo
NCT04610138
Study of ZnAg Liquid Solution to Treat COVID-19 Symptomatic Participants
Covid19
P2
Completed296RCT, Double-blindCNM-ZnAg, Placebo
NCT03815916
31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Parkinson's Disease
Parkinson's Disease
P2
Completed13Open-labelGold Nanocrystals
NCT03843710
31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Amyotrophic Lateral Sclerosis (REPAIR-ALS)
Amyotrophic Lateral Sclerosis
P2
Withdrawn—Open-labelGold Nanocrystals
NCT03993171
31P-MRS Imaging to Assess the Effects of CNM-Au8 on Impaired Neuronal Redox State in Multiple Sclerosis.
Multiple Sclerosis
P2
Completed33Open-labelgold nanocrystals
NCT02755870
A Phase I SAD and MAD Clinical Trial of CNM-Au8 in Healthy Male and Female Volunteers
Healthy Volunteers - Male and Female
P1
Completed86RCT, Double-blind—
NCT05281484
Three Intermediate Expanded Access Protocols (EAP) CNMAu8.EAP01, CNMAu8.EAP02, and CNMAu8.EAP06 for ALS
Amyotrophic Lateral Sclerosis
AVAILABLE——CNM-Au8
NCT04081714
Intermediate Expanded Access Protocol CNMAu8.EAP03
Multiple Sclerosis
TEMPORARILY_NOT_AVAILABLE——CNM-Au8
NCT06408727
Intermediate Expanded Access Protocol CNMAu8.EAP04
ALS, Amyotrophic Lateral Sclerosis
TEMPORARILY_NOT_AVAILABLE——CNM-Au8