Centessa Pharmaceuticals PLC
CNTAHealthcare|Biotechnology|UK
$40.50
+0.00 (+0.00%)
Tangible Book
$3.15
Earnings Power
$1.77
About
Centessa Pharmaceuticals PLC is a clinical-stage biotechnology company pioneering a new class of therapeutics in orexin-based neuroscience. The group is developing a franchise of small molecule orexin receptor 2 (OX2R) agonists designed to address neuroscience diseases underpinned by dysregulation of wakefulness, attention, cognition, mood, and other symptoms, each grounded in the shared biology of the orexin pathway. The company's programs and Pipeline are the Orexin Receptor 2 Agonist Program and LockBody Technology Platform.
Stock Price
+208.5%(1Y)
Pipeline Summary
17 total trials6
Phase 1
8
Phase 2
5
Phase 3
0
Phase 4
Terminated: 10Recruiting: 5Withdrawn: 1Completed: 1
Active Trials (5)
A Study to Investigate the Effects of Cleminorexton Compared With Placebo in the Treatment of Participants With Central Disorders of Hypersomnolence
NCT07598708Narcolepsy Type 1
Phase 2Phase 3Recruiting
Enrollment: 222 participants
A Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia
NCT06752668Narcolepsy Type 1
Phase 2Recruiting
Enrollment: 248 participants
A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia
NCT07096674Narcolepsy Type 1
Phase 2Recruiting
Enrollment: 90 participants
A Study of ORX489 in Healthy Adult Participants, Aged 18 to 60 Years
NCT07413666Healthy Adult Male and Female Volunteers
Phase 1Recruiting
Enrollment: 212 participants
A Study of ORX142 in Healthy Adult Subjects, Including Subjects 18 to 80 Years of Age
NCT07082829Excessive Daytime Sleepiness
Phase 1Recruiting
Enrollment: 208 participants
BioScore
3.9/10
Cautious
Ownership
Recent Insider Trades
Weinhoff Gregory MSELL
2026-03-2623,998 shares @ $30
Anderson Karen M.SELL
2026-03-2641,076 shares @ $30.12
Anderson Karen M.SELL
2026-03-1774,811 shares @ $28.19
Anderson Karen M.SELL
2026-03-13120,029 shares @ $26.25
Anderson Karen M.SELL
2026-03-13120,029 shares @ $26.25
Recent News
2026-07-03 00:30:27
2026-07-01 00:35:23
Data last updated: Jul 13, 2026, 12:39 PM