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GSK

Healthcare|Drug Manufacturers - General|UK

$52.78

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$40.01

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$32.61

Clinical Trials (131)

Trial	Conditions	Phase	Status	Enrollment	Design	Drug
NCT05600777 A 24-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough	Cough, Refractory Chronic Cough	P3	Active	975	RCT, Double-blind	BLU-5937, Placebo
NCT05599191 A 52-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough	Cough, Refractory Chronic Cough	P3	Active	825	RCT, Double-blind	BLU-5937, Placebo
NCT06065462 Safety and Efficacy of Targeting PP2A in Ovarian Clear Cell Carcinoma Using Dostarlimab and LB-100	Ovarian Clear Cell Carcinoma	P1P2	Recruiting	21	Open-label	Dostarlimab, LB-100
NCT03833479 TSR-042 as Maintenance Therapy for Patients With High-risk Locally Advanced Cervical Cancer After Chemo-radiation	Cervical Cancer, Advanced Cancer	P2	Active	134	RCT, Open-label	TSR-042
NCT05489237 First-in-human Study of IDRX-42 in Participants With Metastatic and/or Unresectable Gastrointestinal Stromal Tumors	Gastrointestinal Neoplasms, Gastrointestinal Stromal Tumor (GIST)	P1	Active	276	Open-label	IDRX-42
NCT00160394 Comparison of Duac® Gel And Differin® Gel in Mild to Moderate Acne Vulgaris	Acne Vulgaris	P4	Completed	130	RCT, Single-blind	Duac® Gel / Differin® Gel
NCT00887484 A Comparative Study of the Tolerability of Two Combination Therapies for the Treatment of Acne	Acne Vulgaris	P4	Completed	50	RCT, Single-blind	BENZOYL PEROXIDE/ CLINDAMYCIN, BENZOYL PEROXIDE/ ADAPALENE
NCT00964366 Study to Determine and Compare the Tolerance and Irritation Potential of Topical Acne Medications	Acne Vulgaris	P4	Completed	53	RCT, Single-blind	clindamycin and benzoyl peroxide, Dapsone gel
NCT01015638 Compare the Tolerance of Clindamycin 1% /Benzoyl Peroxide (BPO) 5% Gel to Clindamycin 1.2%/ BPO 2.5% Topical Medications	Acne Vulgaris	P4	Completed	36	RCT, Single-blind	Clindamycin and BPO 5% gel, Clindamycin phosphate and benzoyl peroxide 2.5% gel.
NCT00837213 Comparative Efficacy and Safety of Benzoyl Peroxide Used in Combination With Clindamycin vs. Benzoyl Peroxide Used in Combination With Clindamycin and Doxycycline in the Treatment of Moderate Acne	Acne	P4	Completed	33	RCT, Single-blind	Benzoyl peroxide with clindamycin, Benzoyl peroxide with clindamycin and doxycycline
NCT01933698 Bioequivalence of Two Commercial Amoxicillin Suspensions	Bioequivalence of Amoxicillin	P4	Completed	25	RCT, Double-blind	amoxicillin
NCT01597492 A Study to Evaluate the Effect of Belimumab on Vaccine Responses in Subjects With Systemic Lupus Erythematosus (SLE)	Systemic Lupus Erythematosus	P4	Completed	79	RCT, Open-label	Belimumab plus Early Vaccination, Belimumab plus Late Vaccination
NCT00841776 Comparative Antimicrobial Efficacy of Two Topical Acne Therapies for the Treatment of Facial Acne	Acne	P4	Completed	54	RCT, Single-blind	Duac, Ziana gel
NCT00842153 Evaluation of the Efficacy and Tolerability of Clobetasol Propionate Foam Compared to Vehicle Foam	Psoriasis	P4	Completed	58	RCT, Double-blind	Clobetasol propionate foam, Vehicle foam
NCT00693654 Comparative Study of the Efficacy of SARNA Sensitive Lotion for Treatment of Uremic Itch in Adult Hemodialysis Patients	Pruritis	P4	Completed	28	RCT, Double-blind	Sarna, Cetaphil
NCT01706250 U0289-401: Eight Week, Split-face, Study to Determine and Compare the Efficacy and Tolerability of MAXCLARITY™ II to PROACTIV™	Acne Vulgaris	P4	Completed	20	RCT, Single-blind	—
NCT01632241 Efficacy and Safety of Belimumab in Black Race Patients With Systemic Lupus Erythematosus (SLE)	Systemic Lupus Erythematosus	P4	Completed	503	RCT, Double-blind	Placebo plus standard therapy, Belimumab 10 mg/kg plus standard therapy, Standard therapy
NCT02524665 8 Week Study to Evaluate and Compare the Efficacy and Tolerability of MAXCLARITY II and MURAD To Treat Acne	Acne Vulgaris	P4	Completed	20	RCT, Single-blind	—
NCT00926367 Two-week Study to Compare the Tolerance and Irritation Potential of Two Combination Topical Gel Acne Medications	Acne Vulgaris	P4	Completed	52	RCT, Single-blind	Clindamycin and benzoyl peroxide, benzoyl peroxide 2.5% and adapalene 0.1% gel
NCT00702507 Prospective Two-Year Study to Assess Miconazole Nitrate Resistance in Neonates and Infants	Diaper Rash	P4	Completed	200	Open-label	0.25 % Miconazole Nitrate Ointment
NCT00757523 Evaluation of the Effectiveness, Safety, and Tolerability of Duac Akne Gel and Epiduo Gel in the Treatment of Facial Acne Vulgaris	Acne Vulgaris	P4	Completed	382	RCT, Single-blind	Epiduo Gel, Duac Gel
NCT00852761 A Study to Evaluate the Efficacy and Tolerability of Topical Therapies for the Condition of Plaque-Type Psoriasis	Plaque-Type Psoriasis	P4	Completed	34	RCT, Single-blind	Olux-E Foam, Clobex lotion
NCT01706263 U0289-402: An Open Label, 8 Week Study to Evaluate the Efficacy and Tolerability of MAXCLARITY II in Subjects With Acne	Acne Vulgaris	P4	Completed	28	Open-label	MAXCLARITY II (2.5% BPO) Foam Cleanser, MAXCLARITY II (2.5% BPO) Foam Treatment, MAXCLARITY II (0.5% Salicylic Acid) Toner Foam
NCT01745133 Olux E Foam and Sorilux Foam Combination Therapy for the Maintenance of Treatment Response in Patients With Moderate Plaque Psoriasis	Psoriasis	P4	Completed	63	RCT, Single-blind	vehicle foam, calcipotriene, calcipotriene + clobetasol propionate
NCT01323673 Ethanol-Free Clobetasol Propionate Foam 0.05% (Olux-E Foam) vs Vehicle Foam in the Treatment of Chronic Hand Dermatitis.	Dermatitis, Chronic	P4	Completed	125	RCT, Double-blind	clobetasol propionate 0.05%, Vehicle / Placebo
NCT00240513 Study Comparing Acne in Patients Taking Oral Minocycline to Patients Taking Minocycline Plus Topical Tretinoin	Acne Vulgaris	P4	Terminated	38	RCT, Single-blind	Minocycline, Minocycline plus tretinoin
NCT01016977 A Phase 4, Single-Blind, Randomized, Study to Compare the Tolerability and Efficacy of 0.1% Tazorac Cream When Used in Combination With Either Duac Gel or Acanya Gel for the Treatment of Facial Acne Vulgaris	Acne Vulgaris	P4	Completed	40	RCT, Single-blind	Clindamycin 1%/Benzoyl Peroxide 5% and 0.1% tazarotene, clindamycin phosphate 1.2%/benzoyl peroxide 2.5% and 0.1% tazarotene
NCT00964223 A Study to Evaluate Tolerability of Two Topical Drug Products in the Treatment of Facial Acne	Acne Vulgaris	P4	Completed	28	RCT, Single-blind	Clindamycin and benzoyl peroxide gel (Duac® Topical Gel), benzoyl peroxide and adapalene gel (EPIDUO™ Gel)
NCT00703846 STUDY TO ASSESS THE LONG-TERM SAFETY OF EXTINA (KETOCONAZOLE) FOAM, 2%	Dermatitis, Seborrheic	P4	Completed	498	Open-label	Ketoconazole
NCT00807014 Evaluation of Quality of Life, Efficacy, and Tolerance of Duac® Gel Compared to Differin® Gel in the Treatment of Acne	Acne Vulgaris	P4	Completed	169	RCT, Single-blind	Duac Gel, Differin gel
NCT00832364 Trial of an Injectable Biologic and U0279 as Combination Therapy for Severe Plaque-Type Psoriasis	Plaque Psoriasis	P4	Withdrawn	—	RCT, Single-blind	Acitretin (also called U0279), Placebo, Etanercept
NCT01228409 Low-Dose (17.5 mg/Day) Acitretin: Comparable Efficacy Without the Side Effects?	Psoriasis	P4	Unknown	20	Open-label	Acitretin 17.5 mg/day
NCT00828464 Study to Evaluate Safety, Efficacy and Tolerability of Clobetasol Propionate for Chronic Hand Dermatitis	Hand Dermatosis	P4	Completed	30	Open-label	clobetasol propionate
NCT01639339 Efficacy and Safety of Belimumab in Patients With Active Lupus Nephritis	Lupus Nephritis	P3	Completed	448	RCT, Double-blind	Placebo plus standard therapy, Belimumab 10 mg/kg plus standard therapy, Standard therapy
NCT00712933 A Continuation Trial for Subjects With Lupus That Completed Protocol HGS1006-C1056 or HGS1006-C1057	Systemic Lupus Erythematosus	P3	Completed	738	Open-label	belimumab
NCT02014584 Sexual Function in Men Receiving Dutasteride for Androgenetic Alopecia	Alopecia	P3	Completed	117	RCT, Double-blind	Dutasteride, Placebo
NCT00776919 Trial of Clindamycin / Benzoyl Peroxide Gel in Subjects With Acne	Acne Vulgaris	P3	Completed	1,315	RCT, Double-blind	clindamycin / benzoyl peroxide gel, clindamycin gel, BPO gel, vehicle gel
NCT01663623 Belimumab in Remission of VASculitis	Vasculitis	P3	Completed	106	RCT, Double-blind	Placebo, Belimumab 10 mg/kg, Azathioprine
NCT00088673 Evaluation of 3APS in Patients With Mild to Moderate Alzheimer's Disease	Alzheimer Disease	P3	Unknown	950	RCT, Double-blind	3APS
NCT01017120 A Study to Evaluate the Safety and Efficacy of Tazarotene Foam, 0.1%, in Subjects With Common Facial Acne	Acne Vulgaris	P3	Completed	742	RCT, Double-blind	Tazarotene Foam, Vehicle Foam
NCT00282724 Efficacy and Safety of Two Doses of Liarozole vs. Placebo for the Treatment of Lamellar Ichthyosis	Ichthyosis, Lamellar	P2P3	Completed	98	RCT, Double-blind	Liarozole
NCT01484496 A Study of Belimumab Administered Subcutaneously in Subjects With Systemic Lupus Erythematosus (SLE)	Systemic Lupus Erythematosus	P3	Completed	839	RCT, Double-blind	Placebo, Belimumab 200 mg SC, Standard therapy
NCT00356915 Itraconazole Tablets Vs. Itraconazole Capsules vs. Placebo in Onychomycosis of the Toenail.	Onychomycosis	P3	Completed	1,381	RCT, Single-blind	Itraconazole 100mg capsules, Itraconazole 200mg tablets, Placebo tablets
NCT00817063 Efficacy and Safety of a Retinoid in the Treatment of Severe Chronic Hand Eczema	Eczema	P3	Completed	599	RCT, Double-blind	alitretinoin, Placebo
NCT00689481 Study to Compare U0267 Against Vehicle in Subjects With Plaque-type Psoriasis Two of Two Phase 3 Studies	Psoriasis	P3	Completed	323	RCT, Double-blind	U0267 Foam, Vehicle foam
NCT00724867 A Continuation Trial for Subjects With Lupus Who Completed Protocol HGS1006-C1056 in the United States	Systemic Lupus Erythematosus	P3	Completed	268	Open-label	Belimumab 1 mg/kg, Belimumab 10 mg/kg
NCT00689117 A Clinical Study to Evaluate the Safety and Effectiveness of an Investigational Product Called CT Gel	Acne Vulgaris, Acne	P3	Completed	1,649	RCT, Double-blind	CT Gel, Clindamycin Gel (clindamycin ), Tretinoin Gel (tretinoin), Vehicle Gel
NCT02101268 Efficacy of Momelotinib Versus Best Available Therapy in Anemic or Thrombocytopenic Subjects With Primary Myelofibrosis (MF), Post-polycythemia Vera MF, or Post-essential Thrombocythemia MF	Primary Myelofibrosis (PMF), Post-polycythemia Vera (Post-PV)	P3	Completed	156	RCT, Open-label	Momelotinib, Best Available Therapy (BAT)
NCT01017146 A Study to Evaluate the Safety and Efficacy of Tazarotene Foam, 0.1%, in Subjects With Common Facial Acne - W0260-301	Acne Vulgaris	P3	Completed	744	RCT, Double-blind	Tazarotene foam, Vehicle Foam
NCT00891982 A Clinical Study to Evaluate the Tolerability of a Topical Antibiotic and Retinoid Used in a Combined Regimen With a BPO Wash	Acne Vulgaris	P3	Completed	60	RCT, Single-blind	CTGel/ BPO Wash, Soap Free Cleanser and CTGel
NCT00314912 Open-Label Extension of the Phase III Study With Tramiprosate (3APS) in Patients With Mild to Moderate Alzheimer's Disease	Alzheimer's Disease	P3	Unknown	650	Open-label	Tramiprosate (3APS)
NCT00852540 Retapamulin Versus Linezolid in the Treatment of SITL and Impetigo Due to MRSA	Skin Infections, Bacterial	P3	Completed	410	RCT, Double-blind	Retpamulin Ointment, 1%, Linezolid
NCT00217763 European Study of 3APS in Mild to Moderate Alzheimer's Disease Patients	Alzheimer's Disease	P3	Unknown	930	RCT, Double-blind	3APS
NCT00688519 Study to Compare U0267 Against Vehicle in Subjects With Plaque-type Psoriasis One of Two Phase 3 Studies	Psoriasis	P3	Completed	336	RCT, Double-blind	U0267, Vehicle
NCT00035334 Study of the Safety and Efficacy of NC-503 in Secondary (AA) Amyloidosis	Secondary (AA) Amyloidosis, Rheumatoid Arthritis	P2P3	Completed	150	RCT, Double-blind	NC-503 (Anti-amyloidotic (AA) Agent)
NCT01969838 Momelotinib Versus Ruxolitinib in Subjects With Myelofibrosis	Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis	P3	Completed	432	RCT, Double-blind	Momelotinib, Ruxolitinib, Placebo to match momelotinib, Placebo to match ruxolitinib
NCT04173494 A Study of Momelotinib Versus Danazol in Symptomatic and Anemic Myelofibrosis Participants (MOMENTUM)	Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis	P3	Completed	195	RCT, Double-blind	Momelotinib, Placebo to match danazol, Danazol, Placebo to match momelotinib
NCT01139580 The Purpose of This Study is to Demonstrate the Safety and Effectiveness of Calcipotriene Foam in Subjects With Scalp and Body Psoriasis	Psoriasis	P3	Completed	363	RCT, Double-blind	Calcipotriene Foam, Vehicle Foam
NCT02101021 Gemcitabine and Nab-paclitaxel Combined With Momelotinib in Participants With Previously Untreated Metastatic Pancreatic Ductal Adenocarcinoma	Metastatic Pancreatic Ductal Adenocarcinoma	P3	Terminated	25	Double-blind	Momelotinib, Placebo to match momelotinib, Nab-paclitaxel, Gemcitabine
NCT02515630 Momelotinib in Transfusion-Dependent Adults With Primary Myelofibrosis (PMF) or Post-polycythemia Vera or Post-essential Thrombocythemia Myelofibrosis (Post-PV/ET MF)	Primary Myelofibrosis (PMF), Post-polycythemia Vera (Post-PV) Myelofibrosis	P2	Completed	41	Open-label	MMB
NCT02378038 PNT2258 for Treatment of Patients With Richter's Transformation (Brighton)	Richter's Transformation	P2	Terminated	5	Open-label	PNT2258
NCT01258608 Study of Mapatumumab in Combination With Sorafenib in Subjects With Advanced Hepatocellular Carcinoma	Carcinoma, Hepatocellular	P1P2	Completed	101	RCT, Double-blind	Mapatumumab, Placebo, Sorafenib
NCT01998828 Safety and Efficacy of Momelotinib in Subjects With Polycythemia Vera or Essential Thrombocythemia	Polycythemia Vera, Essential Thrombocythemia	P2	Terminated	39	RCT, Open-label	Momelotinib
NCT01236638 Extension Study Evaluating the Long Term Safety and Efficacy Study of CYT387 in Primary Myelofibrosis (PMF) or Post-polycythemia Vera (PV) or Post-essential Thrombocythemia (ET)	Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis	P2	Completed	120	Open-label	Momelotinib
NCT00920556 A Clinical Study to Assess the Safety and Activity of SRT501 Alone or in Combination With Bortezomib in Patients With Multiple Myeloma	Multiple Myeloma	P2	Terminated	24	Open-label	5.0g SRT501, Bortezomib
NCT00937326 Clinical Study to Assess the Safety and Pharmacokinetics of SRT2104 in Type 2 Diabetic Human Subjects	Diabetes Mellitus, Type 2	P2	Completed	227	RCT, Double-blind	SRT2104, Placebo
NCT00725439 An Open Label Trial to Assess the Safety and Efficacy of Oral R115866 in the Treatment Facial Acne	Acne	P2	Completed	16	Open-label	Talarozole
NCT01733238 Study of PNT2258 for Treatment of Relapsed or Refractory Non-Hodgkin's Lymphoma	Lymphoma, Non-Hodgkin's	P2	Completed	13	Open-label	PNT2258
NCT00675857 A Phase IIa Proof-of-concept Study of NC-503 in Patients With Type II Diabetes	Diabetes Mellitus, Type 2, Metabolic Syndrome X	P2	Completed	200	RCT, Double-blind	NC-503 (eprodisate disodium)
NCT00725348 An Open-Label, Multi-Center Trial in the Treatment of Subjects With Moderate to Severe Plaque Type Psoriasis	Psoriasis	P2	Completed	19	Open-label	Talarozole
NCT03979638 A Dose Escalation Study of BLU-5937 in Unexplained or Refractory Chronic Cough	Chronic Refractory Cough	P2	Terminated	68	RCT, Double-blind	BLU-5937, Placebo
NCT00716144 Dose Ranging Study of the Safety and Efficacy of R115966 in Plaque Psoriasis	Psoriasis	P2	Completed	176	RCT, Double-blind	Talarozole
NCT04693195 A Multiple-Dose Study of BLU-5937 in Chronic Pruritus Associated With Atopic Dermatitis	Chronic Pruritus, Atopic Dermatitis	P2	Completed	142	RCT, Double-blind	BLU-5937, Placebo
NCT00056238 Cerebril™ in Patients With Lobar Hemorrhage Related to Cerebral Amyloid Angiopathy	Stroke, Neurologic Diseases, General	P2	Completed	30	RCT, Double-blind	NC-758 (Anti amyloidotic [Aß] agent)
NCT02226965 PNT2258 for Treatment of Patients With r/r DLBCL (Wolverine)	Lymphoma, Diffuse Large B-Cell	P2	Completed	45	Open-label	PNT2258
NCT00713609 Safety and Efficacy Study of Clindamycin/Benzoyl Peroxide/Tazarotene Cream in Subjects With Acne	Acne Vulgaris	P2	Completed	591	RCT, Double-blind	Benzoyl peroxide gel, Clindamycin gel, Tazarotene cream, Vehicle gel, Vehicle cream
NCT02797964 A Phase 1/2 Trial of SRA737 in Subjects With Advanced Cancer	Advanced Solid Tumors or Non-Hodgkin's Lymphoma (NHL)	P1P2	Completed	107	Open-label	SRA737
NCT02797977 A Phase 1/2 Trial SRA737 in Combination With Gemcitabine and Cisplatin or Gemcitabine Alone in Advanced Cancer Subjects	Advanced Solid Tumors	P1P2	Completed	153	Open-label	SRA737, gemcitabine, cisplatin, SRA737, gemcitabine
NCT01649765 Pediatric Lupus Trial of Belimumab Plus Background Standard Therapy	Systemic Lupus Erythematosus	P2	Completed	93	RCT, Double-blind	Belimumab 10 mg/kg
NCT01154101 Study of the Clinical Activity, Safety, and Tolerability of SRT2104 in Subjects With Moderate to Severe Plaque-Type Psoriasis	Psoriasis	P2	Completed	40	RCT, Double-blind	Placebo, SRT2104
NCT00730405 Efficacy and Safety Study of 4 Dose Regimens of Oral Albaconazole in Subjects With Distal Subungual Onychomycosis	Onychomycosis	P2	Completed	582	RCT, Double-blind	Albaconazole 100mg, Albaconazole 200mg, Albaconazole 400mg, Albaconazole 400mg, Placebo 400 mg
NCT01245140 Efficacy of Alitretinoin Treatment in Patients With Pustular Form of Psoriasis	Psoriasis	P2	Completed	33	RCT, Double-blind	alitretinoin, Placebo
NCT00583362 A Continuation Trial for Subjects With Systemic Lupus Erythematosus That Have Completed Protocol LBSL02	Systemic Lupus Erythematosus	P2	Completed	298	Open-label	Belimumab
NCT01423058 Safety Study Evaluating Twice-Daily Administration of Momelotinib in Primary Myelofibrosis or Post-Polycythemia Vera or Post-Essential Thrombocythemia Myelofibrosis	Primary Myelofibrosis, Post-Polycythemia Vera	P1P2	Completed	61	Open-label	Momelotinib
NCT02124746 Long-term Safety and Efficacy of Momelotinib in Subjects With Primary Myelofibrosis, Post-polycythemia Vera Myelofibrosis, Post-essential Thrombocythemia Myelofibrosis, Polycythemia Vera or Essential Thrombocythemia	Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis	P2	Completed	87	Open-label	Momelotinib
NCT00935987 Safety and Efficacy Study of CYT387 in Primary Myelofibrosis (PMF) or Post-polycythemia Vera (PV) or Post-essential Thrombocythemia (ET)	Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis	P1P2	Completed	166	Open-label	CYT387
NCT02673619 A Study to Evaluate Clinical Effect, Pharmacokinetics , Safety, and Tolerability of Umeclidinium in Palmar Hyperhidrosis Subjects	Hyperhidrosis	P2	Completed	58	RCT, Double-blind	Umeclidinium, Vehicle
NCT04678206 Evaluation of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough	Refractory Chronic Cough	P2	Completed	310	RCT, Double-blind	BLU-5937, Placebo
NCT01604863 A Study of HGS1036 in Combination With Chemotherapy in Subjects With Advanced Solid Malignancies	Cancer	P1	SUSPENDED	54	Open-label	HGS1036 + Paclitaxel + Carboplatin, HGS1036 + Cisplatin + Etoposide, HGS1036 + Docetaxel
NCT01112787 A Study to Evaluate the Irritation Potential of Tazarotene Foam on Skin in Healthy Volunteers	Acne Vulgaris	P1	Completed	39	RCT, Double-blind	Tazarotene Foam, Vehicle Foam, Sodium Laural Sulfate, Distilled Water
NCT05959447 Evaluation of the Potential Drug-drug Interactions Between Gemfibrozil or Dabigatran Etexilate and Camlipixant	Cough, Healthy	P1	Completed	45	Open-label	Camlipixant, Dabigatran etexilate, Gemfibrozil
NCT01340911 A Study in Healthy Male Volunteers to Investigate Different Doses of a New Drug for the Treatment of Metabolic Diseases	Diabetes Mellitus, Type 2	P1	Completed	78	RCT, Single-blind	SRT3025, Placebo
NCT02017899 A Phase 1, Dose Escalation Study, to Evaluate a New Shigella Sonnei Vaccine in Healthy Adults.	Shigellosis	P1	Completed	50	RCT, Double-blind	S. sonnei 1790GAHB, Placebo
NCT00920803 A Clinical Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of SRT501 in Subjects With Colorectal Cancer and Hepatic Metastases	Neoplasms, Colorectal	P1	Completed	9	RCT, Double-blind	Placebo, SRT501
NCT05899829 Evaluation of the Effect of Rifampin and Rabeprazole on the Pharmacokinetics of Camlipixant	Cough, Healthy	P1	Completed	42	Open-label	Camlipixant, Rabeprazole, Rifampin
NCT01416376 Effect of Multiple Dose Levels of SRT2379 on Endotoxin-Induced Inflammation	Sepsis	P1	Completed	39	RCT, Double-blind	SRT2379, Placebo
NCT06179537 Evaluation of the Pharmacokinetics and Safety of BLU-5937 in Healthy Adult Japanese and Caucasian Subjects	Healthy	P1	Completed	34	RCT, Double-blind	BLU-5937
NCT02206763 Erlotinib and Momelotinib for the Treatment of Epidermal Growth Factor Receptor (EGFR) Mutated EGFR Tyrosine Kinase Inhibitor (TKI) Naive Metastatic Non-Small Cell Lung Cancer (NSCLC)	EGFR Mutated EGFR TKI Naive Metastatic NSCLC	P1	Terminated	11	Open-label	Momelotinib (MMB), Erlotinib
NCT01132443 W0261-101: A Phase 1, Single Center, Randomized, Open-Label Study to Evaluate the Bioavailability of Clindamycin From Clindamycin 1%-Benzoyl Peroxide 3% Gel, Topical Gel (Clindamycin 1%- Benzoyl Peroxide 5%), and Once Daily Gel (Clindamycin 1%-Benzoyl Peroxide 5%) in Subjects With Acne	Acne Vulgaris	P1	Completed	72	RCT, Open-label	Clindamycin 1%-Benzoyl Peroxide (BPO) 3% Gel,
NCT00938275 A Clinical Study to Assess the Effect of Food and Gender on the Pharmacokinetics of SRT2104 Administered as an Oral Suspension or Capsule Formulation to Normal Healthy Volunteers	Diabetes Mellitus, Type 2	P1	Completed	20	RCT, Open-label	0.5g SRT2104
NCT00712855 A Study of Mapatumumab in Combination With Sorafenib in Subjects With Advanced Hepatocellular Carcinoma	Hepatocellular Carcinoma	P1	Completed	23	Open-label	mapatumumab, sorafenib
NCT01031108 A Clinical Trial to Assess the Safety of Oral SRT2104 and Its Effects on Vascular Dysfunction in Otherwise Healthy Cigarette Smokers and Subjects With Type 2 Diabetes Mellitus	Diabetes Mellitus, Type 2	P1	Completed	38	RCT, Double-blind	Placebo, SRT2104
NCT00933530 A Clinical Study to Assess the Safety and Pharmacokinetics of SRT2104 in Normal Healthy Male Volunteers	Diabetes Mellitus, Type 2, Healthy Volunteer	P1	Completed	43	RCT, Single-blind	SRT2104, Placebo
NCT05244759 Mass Balance Recovery, Absorption, Metabolism and Excretion of [14C]-BLU-5937	Healthy	P1	Completed	6	Open-label	[14C]-BLU-5937
NCT03638180 BLU-5937: First-in-Human, Single and Multiple Doses Escalation, Safety, Tolerability, Pharmacokinetics and Food Effect	Cough	P1	Completed	90	RCT, Double-blind	BLU-5937, Placebo
NCT01115322 A Study to Evaluate the Potential of Tazarotene Foam to Cause a Reaction When Applied to the Skin and Exposed to Light on Healthy Volunteers	Acne Vulgaris	P1	Completed	38	RCT, Single-blind	Tazarotene Foam without irradiation, Tazarotene Foam with UVA and UVB irradiation, Tazarotene Foam with UVA, UVB, and visible light, Vehicle Foam without irradiation, Vehicle Foam with UVA and UVB irradiation, Vehicle Foam with UVA and UVB and visible light irradiation, No Treatment without irradiation, No Treatment with UVA and UVB irradiation, No Treatment with UVA and UVB and visible light irradiation
NCT02411162 A Single Dose Phase I Exploratory Study in Healthy Volunteers With GSK2894512 Cream	Dermatitis, Atopic	P1	Completed	15	Open-label	Combination therapy GSK2894512 Cream A + GSK2894512 Cream B, Combination therapy Vehicle Cream A + Vehicle Cream B
NCT00509275 A Study to Evaluate Efficacy and Safety of Three W0027 Regimens in the Treatment of Moccasin Type Tinea Pedis (MTTP)	Tinea Pedis	P1	Completed	120	RCT, Double-blind	W0027, Placebo
NCT01262911 Effect of SRT2379 on Endotoxin-Induced Inflammation	Sepsis	P1	Completed	17	RCT, Double-blind	SRT2379, Placebo
NCT02034500 Evaluate a New Shigella Sonnei Vaccine Administered Either by Intradermal, Intranasal or Intramuscular Route in Healthy Adults	Shigellosis	P1	Completed	52	RCT, Double-blind	S. sonnei 1790GAHB, Placebo
NCT01039883 A Study to Compare the Blood Levels of Albaconazole in Healthy Subjects Who Have Received a Single Dose of 400 mg Albaconazole as a Tablet Versus Albaconazole as a Capsule	Onychomycosis	P1	Completed	40	RCT, Open-label	Albaconazole tablet 400mg, Albaconazole 100mg capsules, then albaconazole 400mg tablet
NCT06222892 A Study of Camlipixant in Male and Female Healthy Participants and Participants With Hepatic Impairment Aged 18-75 Years of Age	Cough	P1	Completed	32	Open-label	Camlipixant
NCT01453491 A Phase 1b Study to Assess the Safety and Anti-inflammatory Effects of Two Different Doses of SRT2104 in Patients With Ulcerative Colitis	Colitis, Ulcerative	P1	Completed	17	RCT, Double-blind	SRT2104
NCT02244489 Momelotinib Combined With Capecitabine and Oxaliplatin in Adults With Relapsed/Refractory Metastatic Pancreatic Ductal Adenocarcinoma	Relapsed/Refractory Metastatic Pancreatic Ductal Adenocarcinoma	P1	Terminated	16	Open-label	Momelotinib (MMB), Capecitabine, Oxaliplatin
NCT00695071 Study to Assess Blood Levels of Itraconazole During a Two-Week Period	Healthy	P1	Completed	16	Open-label	Itraconazole
NCT06497517 A Study to Investigate the Effect of Food on Camlipixant Concentrations in Healthy Participants	Cough	P1	Completed	14	RCT, Open-label	GSK5464714- Camlipixant
NCT02258607 Efficacy and Safety of Momelotinib Combined With Trametinib in Adults With Metastatic KRAS-mutated Non-Small Cell Lung Cancer (NSCLC) Who Have Failed Platinum-Based Chemotherapy Preceded by a Dose-finding Lead-in Phase	Relapsed Metastatic KRAS-Mutated Non-Small Cell Lung Cancer	P1	Terminated	21	Open-label	Momelotinib (MMB), Trametinib
NCT01114841 A Study To Evaluate The Contact Sensitization Potential Of Tazarotene Foam On Skin In Healthy Volunteers	Acne Vulgaris	P1	Completed	254	RCT, Single-blind	Tazarotene Foam, Vehicle Foam
NCT05570539 Assessment of the Pharmacokinetics of BLU-5937 Extended Release Prototypes and a BLU-5937 Immediate Release Reference Formulation	Cough, Healthy	P1	Completed	30	Open-label	BLU-5937 IR, BLU-5937 ER
NCT01191775 A Study of PNT2258 in Patients With Advanced Solid Tumors	Cancer, Lymphoma	P1	Completed	22	Open-label	PNT2258
NCT01984775 A Study to Evaluate the Irritation Potential of GSK2894512 Cream on Skin in Healthy Subjects	Psoriasis	P1	Completed	52	RCT, Double-blind	GSK2894512 cream, Vehicle cream, Positive control, Negative control
NCT01929278 W0265-103: A Single-Center, Evaluator-Blinded, Randomized, Placebo Controlled, Phase 1 Clinical Trial Evaluating The Phototoxic Potential Of Topically Applied Clindamycin 1.0% - Tretinoin 0.025% Gel (Ct Gel) In Healthy Volunteers	Acne Vulgaris	P1	Completed	37	RCT, Single-blind	CT Gel (clindamycin 1% and tretinoin 0.025%)
NCT01702493 A Study to Assess the Relative Bioavailability of New Oral Formulations of SRT2104 in Healthy Male Volunteers	Psoriasis	P1	Completed	16	RCT, Open-label	Cap SRT2104, Tab SRT2104 slow release, Tab SRT2104 intermediate release, Tab SRT2104 fast release, Selected formulations of SRT2104 from Part 1, Selected formulations of SRT2104 from Part 1 single alternative dose
NCT01014962 A Study of the Effects of Increasing Doses of a Drug for the Treatment of Nail Fungus	Onychomycosis	P1	Completed	24	RCT, Double-blind	Albaconozole, Placebo, Albaconozole, Placebo, Albaconozole, Placebo
NCT00937872 A Clinical Study to Evaluate the Pharmacokinetics and the Absolute Bioavailability of SRT2104 Given as a 250mg Oral Suspension and Intravenous Microdose of 100 µg Carbon-14 Radio-labeled SRT2104 in Healthy Male Subjects	Diabetes Mellitus, Type 2	P1	Completed	9	Open-label	250 mg SRT2104 Suspension, Carbon-14 radio-labeled SRT2104
NCT01019603 A Study to Evaluate the Bioavailability of Tazarotene Foam, 0.1%, and Tazorac Gel, 0.1%, in Subjects With Acne Vulgaris	Acne Vulgaris	P1	Completed	30	RCT, Open-label	Tazarotene, Tazaroc Gel
NCT00719121 Study on Anti-inflammatory Effects of Topical R115866 Gel	Cutaneous Inflammation	P1	Completed	12	RCT, Single-blind	Talarozole, Differin™, 0.1% adapalene gel
NCT01119651 A Study to Evaluate the Potential of Tazarotene Foam to Cause an Allergic Reaction When Applied to the Skin and Exposed to Light on Healthy Volunteers.	Acne Vulgaris	P1	Completed	59	RCT, Single-blind	Tazarotene (Patch application in Challenge Phase)
NCT00931086 Expanded Access Trial of Belimumab Antibody in RA Patients Who Were Previously Treated Under HGS Protocol LBRA99	Rheumatoid Arthritis		NO_LONGER_AVAILABLE	—	—	belimumab
NCT01446237 U0289-405: An Open-Label, 12-Week Study to Evaluate the Efficacy and Safety of the Acne System (Benzoyl Peroxide 2.5%, Salicylic Acid 0.5%) in Subjects With Acne	Acne Vulgaris	N/A	Completed	125	Open-label	—
NCT01858792 A Pooled Analysis of the HGS1006-C1056 (BLISS-52) and HGS1006-C1057 (BLISS-76) Studies	Lupus Erythematosus, Discoid		Completed	1	—	Belimumab 1 mg/kg, Belimumab 10 mg/kg