KPTI logo

Karyopharm Therapeutics Inc.

KPTI
Healthcare|Biotechnology|US
$0.05
-0.01 (-8.65%)
Cash / Share
$2.25

Analyst Consensus

Buy21 analysts
Strong Buy
0
Buy
13
Hold
6
Sell
2
Strong Sell
0
Consensus Target
$7.33
Implied Upside
+13251.5%
Low Target
$3.00
High Target
$16.00

Price Target Trend

Last Month
—
0 targets
Last Quarter
—
0 targets
Last Year
$12.88
8 targets · +23361% vs price
All Time
$12.13
16 targets · +21995% vs price

Rating Trend

Dec 25
5 buy · 1 hold · 0 sell
Jan 26
5 buy · 1 hold · 0 sell
Feb 26
6 buy · 1 hold · 0 sell
Mar 26
6 buy · 1 hold · 0 sell
Apr 26
6 buy · 1 hold · 0 sell
May 26
6 buy · 1 hold · 0 sell
Jun 26
6 buy · 1 hold · 0 sell
Jul 26
6 buy · 2 hold · 0 sell
Aug 26
4 buy · 2 hold · 0 sell
Sep 26
4 buy · 2 hold · 0 sell
Oct 26
4 buy · 1 hold · 0 sell
Nov 26
4 buy · 1 hold · 0 sell

Recent Price Targets

DateFirmAnalystTargetPrice ThenSource
Jul 31, 2026H.C. WainwrightRobert Burns$3.00(-57%)$7.01TheFly
Jul 31, 2026Robert W. Baird$3.00(-57%)$7.01TheFly
Jul 21, 2026RBC CapitalBrian Abrahams$16.00(+97%)$8.11StreetInsider
May 6, 2026H.C. Wainwright$13.00(+38%)$9.41TheFly
Apr 27, 2026Piper Sandler$16.00(+85%)$8.66TheFly
Mar 9, 2026UBS$28.00(+230%)$8.49TheFly
Dec 17, 2025Goldman Sachs$12.00(+90%)$6.33StreetInsider
Dec 17, 2025Piper Sandler$12.00(+90%)$6.33StreetInsider
Nov 4, 2025RBC CapitalBrian Abrahams$19.00(+239%)$5.60TheFly
Oct 13, 2025H.C. WainwrightRobert Burns$15.00(+173%)$5.50TheFly
Oct 9, 2025Robert W. Baird$21.00(+256%)$5.90TheFly
Oct 8, 2025Leerink Partners$6.00(+2%)$5.91TheFly
Jun 10, 2024RBC CapitalBrian Abrahams$3.00(+215%)$0.95StreetInsider
Jan 10, 2023Leerink Partners$5.00(+76%)$2.84Benzinga
Aug 23, 2022Robert W. BairdCollen Kusy$14.00(+152%)$5.56Pulse 2.0
Mar 10, 2022RBC CapitalBrian Abrahams$8.00(+23%)$6.49Pulse 2.0

Recent Rating Actions

FirmActionRatingDate
Rodman & RenshawdowngradeBuy →NeutralNov 2, 2026
HC Wainwright & Co.downgradeBuy →NeutralJul 31, 2026
Piper SandlermaintainOverweightJul 31, 2026
HC Wainwright & Co.maintainBuyMay 6, 2026
Piper SandlermaintainOverweightApr 27, 2026
Piper SandlermaintainOverweightMar 30, 2026
HC Wainwright & Co.maintainBuyMar 25, 2026
BairdmaintainOutperformMar 25, 2026
HC Wainwright & Co.maintainBuyFeb 18, 2026
RBC CapitalmaintainOutperformNov 4, 2025
HC Wainwright & Co.upgradeNeutral →BuyOct 13, 2025
BairdmaintainOutperformOct 9, 2025
Piper SandlermaintainOverweightOct 9, 2025
BairdmaintainOutperformAug 12, 2025
HC Wainwright & Co.downgradeBuy →NeutralJul 16, 2025
RBC CapitalmaintainOutperformMay 13, 2025
BairdmaintainOutperformMay 13, 2025
BarclaysmaintainOverweightMay 13, 2025
BairdmaintainOutperformMar 3, 2025
HC Wainwright & Co.maintainBuyFeb 26, 2025
HC Wainwright & Co.maintainBuyFeb 20, 2025
RBC CapitalmaintainOutperformFeb 20, 2025
RBC CapitalmaintainOutperformFeb 10, 2025
HC Wainwright & Co.maintainBuyJan 15, 2025
HC Wainwright & Co.maintainBuyNov 6, 2024

Earnings History

Next report: Feb 10, 2027 · EPS est. $-0.74
Report DateEPS ActualEPS Est.Revenue ActualRevenue Est.
Aug 13, 2026$-2.32$-1.37$33.4M$32.2M
May 14, 2026$-1.24$-1.45$35.1M$31.4M
Feb 12, 2026$-5.68$-2.26$34.1M$35.1M
Nov 3, 2025$-3.82$-3.47$44.0M$42.1M
Aug 11, 2025$-4.32$-3.80$37.9M$38.0M
May 12, 2025$-2.77$-4.21$30.0M$35.1M
Feb 19, 2025$-3.60$-0.25$30.5M$35.7M
Nov 5, 2024$-3.90$-3.94$38.8M$37.9M

News

Karyopharm to Present Selinexor Data in Patients with Myelofibrosis and Multiple Myeloma at the 68th American Society of Hematology Annual Meeting and Exposition (ASH)

– Week 48 Data from the Phase 3 SENTRY Trial Selected for Oral Presentation – – Data from the Phase 2 SENTRY-2 Trial Selected for Oral Presentation – NEWTON, Mass., Nov. 4, 2026 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI) ("Karyopharm" or the "Company"), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that abstracts from two of its clinical trials evaluating selinexor in patients with myelofibrosis were selected for oral presentations …

Nov 4, 2026prnewswire.com
Karyopharm Therapeutics Inc. Announces Planned Merger with Ayrmid Ltd. to Strengthen Company for the Future

– The Company Remains Focused on Supporting Patients and Advancing its Programs in Multiple Myeloma and Myelofibrosis – – Ayrmid will Serve as Lead Bidder in Court-Supervised Sale Process to Maximize Business Value for all Stakeholders – – The Company Receives a Commitment of $55 Million in Additional Financing and Ongoing Operations Are Expected to be Uninterrupted During Sale Process – NEWTON, Mass., Nov. 2, 2026 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI) ("Karyopharm" or the …

Nov 2, 2026prnewswire.com
Karyopharm Therapeutics Reports Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)

NEWTON, Mass., Oct. 1, 2026 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that the Company granted 333 restricted stock units (RSUs) to one newly-hired employee.

Oct 1, 2026prnewswire.com
Reviewing Alpha Cognition (NASDAQ:ACOG) & Karyopharm Therapeutics (NASDAQ:KPTI)

Karyopharm Therapeutics (NASDAQ: KPTI - Get Free Report) and Alpha Cognition (NASDAQ: ACOG - Get Free Report) are both small-cap healthcare companies, but which is the better business? We will contrast the two companies based on the strength of their institutional ownership, earnings, valuation, profitability, dividends, risk and analyst recommendations. Analyst Ratings This is a breakdown of

Sep 30, 2026defenseworld.net
Karyopharm Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

NEWTON, Mass., Sept. 1, 2026 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that the Company granted an aggregate of 1,850 restricted stock units (RSUs) to two newly-hired employees.

Sep 1, 2026prnewswire.com
Karyopharm Submits Supplemental New Drug Application to the FDA for XPOVIO® (selinexor) Plus Ruxolitinib for Patients with Myelofibrosis

Karyopharm Submits Supplemental New Drug Application to the FDA for XPOVIOÂ (selinexor) Plus Ruxolitinib for Patients with Myelofibrosis

Aug 31, 2026gurufocus.com
Karyopharm Submits Supplemental New Drug Application to the FDA for XPOVIO® (selinexor) Plus Ruxolitinib for Patients with Myelofibrosis

– sNDA Submitted under the Accelerated Approval Pathway; Priority Review Requested – NEWTON, Mass., Aug. 31, 2026 /PRNewswire/ -- Karyopharm Therapeutics Inc. (Nasdaq: KPTI), a commercial-stage pharmaceutical company pioneering novel cancer therapies, today announced that it has submitted a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) seeking Accelerated Approval for XPOVIO® (selinexor) in combination with ruxolitinib for patients with myelofibrosis.

Aug 31, 2026prnewswire.com
INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Karyopharm Therapeutics Inc. - KPTI

NEW YORK, Aug. 27, 2026 /PRNewswire/ -- Pomerantz LLP is investigating claims on behalf of investors of Karyopharm Therapeutics Inc. ("Karyopharm" or the "Company") (NASDAQ: KPTI).  Such investors are advised to contact Danielle Peyton at newaction@pomlaw.com or 646-581-9980, ext.

Aug 27, 2026prnewswire.com
INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Karyopharm Therapeutics Inc. - KPTI

NEW YORK, Aug. 25, 2026 (GLOBE NEWSWIRE) -- Pomerantz LLP is investigating claims on behalf of investors of Karyopharm Therapeutics Inc. (“Karyopharm” or the “Company”) (NASDAQ: KPTI).   Such investors are advised to contact Danielle Peyton at newaction@pomlaw.com or 646-581-9980, ext. 7980.

Aug 25, 2026globenewswire.com
INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Karyopharm Therapeutics Inc. - KPTI

NEW YORK, Aug. 20, 2026 /PRNewswire/ -- Pomerantz LLP is investigating claims on behalf of investors of Karyopharm Therapeutics Inc. ("Karyopharm" or the "Company") (NASDAQ: KPTI).  Such investors are advised to contact Danielle Peyton at newaction@pomlaw.com or 646-581-9980, ext.

Aug 20, 2026prnewswire.com
INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Karyopharm Therapeutics Inc. - KPTI

NEW YORK, Aug. 18, 2026 (GLOBE NEWSWIRE) -- Pomerantz LLP is investigating claims on behalf of investors of Karyopharm Therapeutics Inc. (“Karyopharm” or the “Company”) (NASDAQ: KPTI).   Such investors are advised to contact Danielle Peyton at newaction@pomlaw.com or 646-581-9980, ext. 7980.

Aug 18, 2026globenewswire.com
Karyopharm Therapeutics Inc. (KPTI) Q2 2026 Earnings Call Transcript

Karyopharm Therapeutics Inc. (KPTI) Q2 2026 Earnings Call Transcript

Aug 13, 2026seekingalpha.com
INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Karyopharm Therapeutics Inc. - KPTI

NEW YORK, Aug. 13, 2026 /PRNewswire/ -- Pomerantz LLP is investigating claims on behalf of investors of Karyopharm Therapeutics Inc. ("Karyopharm" or the "Company") (NASDAQ: KPTI).  Such investors are advised to contact Danielle Peyton at newaction@pomlaw.com or 646-581-9980, ext.

Aug 13, 2026prnewswire.com
Karyopharm Therapeutics (KPTI) Reports Q2 Loss, Beats Revenue Estimates

Karyopharm Therapeutics (KPTI) came out with a quarterly loss of $2.32 per share versus the Zacks Consensus Estimate of a loss of $1.53. This compares to a loss of $4.32 per share a year ago.

Aug 13, 2026zacks.com
Karyopharm Reports Second Quarter 2026 Financial Results and Highlights Continued Progress Toward Myelofibrosis sNDA Submission

– Planned August sNDA Submission for Selinexor in Combination with Ruxolitinib in Myelofibrosis under the Accelerated Approval Pathway Remains on Track – – Planned sNDA for Selinexor plus Ruxolitinib Supported by Phase 3 SENTRY Results Presented at ASCO and EHA and Published in the Journal of Clinical Oncology; Potential to Become the First Approved Combination Therapy for Patients with Myelofibrosis – – Total Revenue was $33.4 Million, and U.S. XPOVIO® (selinexor) Net Product Revenue was $30.8 …

Aug 13, 2026prnewswire.com
INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Karyopharm Therapeutics Inc. - KPTI

NEW YORK, Aug. 11, 2026 (GLOBE NEWSWIRE) -- Pomerantz LLP is investigating claims on behalf of investors of Karyopharm Therapeutics Inc. (“Karyopharm” or the “Company”) (NASDAQ: KPTI). Such investors are advised to contact Danielle Peyton at newaction@pomlaw.com or 646-581-9980, ext. 7980.

Aug 11, 2026globenewswire.com
Karyopharm to Report Second Quarter 2026 Financial Results on August 13, 2026

-- Conference Call Scheduled for Thursday, August 13, 2026, at 8:00 a.m. ET -- NEWTON, Mass.

Aug 10, 2026prnewswire.com