MeiraGTx Holdings PLC
MGTXHealthcare|Biotechnology|USA
$13.38
-0.56 (-3.98%)
About
MeiraGTx Holdings PLC is a vertically integrated, clinical-stage genetic medicines company focused on developing targeted therapies for diseases with high unmet need, including radiation-induced xerostomia, Parkinson's disease, and AIPL1-associated retinal dystrophy. The company's pipeline is supported by end-to-end in-house manufacturing capabilities, including GMP viral vector production, plasmid manufacturing, and quality control, enabling development from IND to commercial supply. It also utilizes proprietary platforms in viral vector optimization and riboswitch-based gene regulation to enhance efficacy and reduce dosage. The company operates in the United States, the United Kingdom, and the European Union.
Stock Price
+55.2%(1Y)
Pipeline Summary
16 total trials8
Phase 1
8
Phase 2
0
Phase 3
0
Phase 4
Active: 3Completed: 10Terminated: 1ENROLLING_BY_INVITATION: 1Recruiting: 1
Active Trials (4)
Safety of a Single Administration of AAV2hAQP1, an Adeno-Associated Viral Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in People With Irradiation-Induced Parotid Salivary Hypofunction
NCT02446249Squamous Cell Head and Neck Cancer
Phase 1Active
Enrollment: 17 participants
Long-Term Follow-Up Study of AAV2hAQP1 for Radiation Induced Xerostomia
NCT05060341Radiation-induced Xerostomia
Active
Enrollment: 22 participants
A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia
NCT05926765Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands
Phase 2Recruiting
Enrollment: 276 participants
Long-term Follow-up of Glutamic Acid Decarboxylase (GAD) Gene Transfer in Parkinson's Disease
NCT05894343Parkinson's Disease
Phase 1Phase 2Active
Enrollment: 13 participants
BioScore
5.8/10
Watchlist
Ownership
Recent Insider Trades
Naylor StuartSELL
2026-07-0727,659 shares @ $14.8
Forbes AlexandriaSELL
2026-05-1962,000 shares @ $9.17
Giroux RichardSELL
2026-04-2156,000 shares @ $10.22
Naylor StuartSELL
2026-04-0727,661 shares @ $9.36
Forbes AlexandriaSELL
2026-03-2462,000 shares @ $7.41
Recent News
2026-07-08 16:07:36
2026-07-08 14:54:43
2026-07-08 04:00:20
Data last updated: Jul 13, 2026, 12:47 PM