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Palisade Bio, Inc.

PALI
Healthcare|Biotechnology|US
$1.13
-0.03 (-2.59%)
DCF Value
$2.39
Tangible Book / Share
$0.58
Cash / Share
$0.59

About

Palisade Bio, Inc., a clinical-stage biopharmaceutical company, engages in developing oral phosphodiesterase-4 inhibitor prodrugs designed for targeted delivery to the terminal ileum and colon in the United States. Its lead clinical product candidate includes PALI-2108, which is in phase 1b clinical trial to treat patients with inflammatory bowel disease, including ulcerative colitis and Fibrostenotic Crohn’s disease. The company has a research collaboration and license agreement with Giiant Pharma, Inc. for the development, manufacture, and commercialization of its compounds; license agreement with the Regents of the University of California for sole purpose of maintaining the Newsoara Co-Development; and a co-development and distribution agreement with Newsoara Biopharma Co., Ltd. The company was founded in 2001 and is headquartered in Denver, Colorado.

Stock Price

-31.9%(1Y)
1M
-22.1%
3M
-46.4%
6M
-37.2%
YTD
-51.9%
1Y
-36.2%
3Y
-86.0%
5Y
-99.9%

Pipeline Summary

7 total trials
2
Phase 1
4
Phase 2
1
Phase 3
0
Phase 4
Terminated: 2Active: 1Completed: 2Withdrawn: 1Recruiting: 1

Active Trials (2)

A Study of PALI-2108 in Healthy Volunteers, Patients With Ulcerative Colitis, and Patients With Fibrostenosing Crohn's Disease
NCT07428096Fibrostenotic Crohn's Disease
Phase 1Active
Enrollment: 6 participants
A Trial to Investigate PALI-2108 Versus Placebo in Participants With Moderately to Severely Active Ulcerative Colitis
NCT07845487Ulcerative Colitis (UC)
Phase 2Recruiting
Enrollment: 204 participants

Key Facts

Market Cap$196.9M
Employees14 (+75% YoY)
CEOJ. D. Finley
IPO DateMar 30, 2007
Beta1.62
52-Week Range$1.08 – $2.86
Avg Volume2,957,893
ExchangeNASDAQ

Ownership

Float92.2%
Shares Outstanding174.3M

Recent Insider Trades

Capers Julien E.AWARD
Oct 19, 2026787,300 shares
Capers Julien E.OTHER
Oct 19, 20260 shares
Jones Mitchell LawrenceOPTION EX.
Oct 6, 20262,555,266 shares
Jones Mitchell LawrenceOPTION EX.
Oct 6, 20262,620,850 shares
Jones Mitchell LawrenceTAX W/H
Oct 6, 20261,031,102 shares @ $1.49

Peers

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$10.6M
Data last updated: Nov 9, 2026, 04:27 AM