PALI logo

Palisade Bio, Inc.

PALI
Healthcare|Biotechnology|US
$1.13
-0.03 (-2.59%)
DCF Value
$2.39
Tangible Book / Share
$0.58
Cash / Share
$0.59

Analyst Consensus

Buy4 analysts
Strong Buy
0
Buy
4
Hold
0
Sell
0
Strong Sell
0
Consensus Target
$4.50
Implied Upside
+298.2%
Low Target
$2.00
High Target
$7.00

Price Target Trend

Last Month
—
0 targets
Last Quarter
—
0 targets
Last Year
$4.50
2 targets · +298% vs price
All Time
$3.50
3 targets · +210% vs price

Rating Trend

Dec 25
4 buy · 0 hold · 0 sell
Jan 26
5 buy · 0 hold · 0 sell
Feb 26
6 buy · 0 hold · 0 sell
Mar 26
7 buy · 0 hold · 0 sell
Apr 26
8 buy · 0 hold · 0 sell
May 26
7 buy · 0 hold · 0 sell
Jun 26
8 buy · 0 hold · 0 sell
Jul 26
9 buy · 0 hold · 0 sell
Aug 26
9 buy · 0 hold · 0 sell
Sep 26
9 buy · 0 hold · 0 sell
Oct 26
10 buy · 0 hold · 0 sell
Nov 26
10 buy · 0 hold · 0 sell

Recent Price Targets

DateFirmAnalystTargetPrice ThenSource
Jun 30, 2026Oppenheimer$7.00(+214%)$2.23StreetInsider
Jun 30, 2026H.C. Wainwright$2.00(-10%)$2.23StreetInsider
Nov 17, 2023Maxim GroupNaz Rahman$1.50(-83%)$9.07StreetInsider

Recent Rating Actions

FirmActionRatingDate
HC Wainwright & Co.maintainBuyOct 13, 2026
HC Wainwright & Co.maintainBuySep 23, 2026
Brookline CapitalmaintainBuyMay 13, 2025
Maxim GroupmaintainBuyNov 13, 2024
Maxim GroupmaintainBuyMay 1, 2024
Maxim GroupmaintainBuyApr 16, 2024
Maxim GroupupgradeHold →BuyNov 17, 2023
Ladenburg ThalmannmaintainBuyMay 16, 2023
Maxim GroupupgradeHold →BuyMar 30, 2023
Maxim GroupdowngradeBuy →HoldAug 19, 2022
Ladenburg ThalmannmaintainBuyFeb 2, 2022
Maxim GroupmaintainBuyAug 31, 2021

Earnings History

Report DateEPS ActualEPS Est.Revenue ActualRevenue Est.
Aug 10, 2026$-0.05$-0.05$500.0K$500.0K
May 12, 2026$-0.05$-0.04——
Mar 23, 2026$-0.04$-0.02——
Nov 10, 2025$-0.38$-0.32——
Aug 11, 2025$-0.58$-0.48——
May 12, 2025$-0.47$-0.84——
Mar 25, 2025$-2.39$-1.99——
Nov 12, 2024$-2.32$-3.35——

News

Palisade: Initiating 'Buy' On PALI-2108 UC Study Start And Differentiated PDE4 Inhibitor

I initiate Palisade Bio with a "Buy" rating, driven by its differentiated oral PDE4 inhibitor prodrug PALI-2108 targeting inflammatory bowel diseases. PALI's phase 2b ASCENTRA-UC trial for ulcerative colitis has begun dosing, with 12-week topline results expected in Q4 2027, offering a catalyst. Expansion opportunities include a phase 2a trial in Crohn's disease [Q1 2027 start, Q1 2028 data] and potential in fibrostenotic Crohn's, leveraging proven PDE4 biology.

Nov 2, 2026seekingalpha.com
Palisade Bio Announces First Patient Dosed in Global Phase 2b ASCENTRA-UC Study Evaluating Once-Daily Oral PALI-2108 for the Treatment of Ulcerative Colitis

PALI-2108 is an investigational, gut-activated, once-daily oral PDE4 inhibitor prodrug designed for sustained exposure and anti-inflammatory activity with the potential to improve tolerability

Oct 28, 2026globenewswire.com
Palisade Bio Presents Rapid Endoscopic Improvement and New Translational Evidence for PALI-2108 in Inflammatory Bowel Disease at UEG Week 2026

Five-patient Phase 1b Crohn's disease cohort showed a 47.5% reduction in mean endoscopic disease activity and a 58.8% reduction in mean fecal calprotectin after 14 days

Oct 20, 2026globenewswire.com
Palisade Bio Presents New Clinical, Pharmacokinetic, Pharmacodynamic and Mechanistic Data Strengthening the Phase 2 Rationale for PALI-2108 in Ulcerative Colitis and Crohn’s Disease at ACG 2026

Five presentations connect targeted intestinal exposure and sustained systemic drug exposure with PDE4 target engagement and early clinical activity, supporting ongoing Phase 2 development Two presentations selected for ACG Presidential Poster Awards, a distinction received by approximately 5% of accepted abstracts Microbiome and transcriptomic analyses support the delivery platform and a potential precision medicine approach Denver, CO, Oct.

Oct 12, 2026globenewswire.com
Palisade Bio, Inc. (NASDAQ:PALI) Stock Has Average Target Price of $9.83 According to Analysts

Palisade Bio, Inc. (NASDAQ: PALI - Get Free Report) has been given a consensus rating of "Buy" by the ten ratings firms that are currently covering the firm, MarketBeat Ratings reports. One research analyst has rated the stock with a sell rating, seven have given a buy rating and two have issued a strong buy rating

Oct 3, 2026defenseworld.net
Palisade Bio to Present Clinical and Translational Data for PALI-2108 in Ulcerative Colitis and Crohn's Disease at UEG Week 2026

Oral presentation to highlight early endoscopic improvement and evidence of PDE4 target engagement in fibrostenotic Crohn's disease

Sep 28, 2026globenewswire.com
Palisade Bio Advances PALI-2108 Into Phase II for Ulcerative Colitis and Crohn’s

Palisade Bio (NASDAQ: PALI) said it is advancing its lead drug candidate, PALI-2108, into Phase II studies for ulcerative colitis and Crohn's disease after completing its Phase I program. Chief Executive Officer JD Finley said PALI-2108 is a once-daily oral phosphodiesterase 4, or PDE4, inhibitor designed as a prodrug that is bioactivated in the terminal ileum

Sep 28, 2026defenseworld.net
Palisade Bio Advances PALI-2108 Into Phase II for Ulcerative Colitis and Crohn's

Palisade Bio NASDAQ: PALI said it is advancing its lead drug candidate, PALI-2108, into Phase II studies for ulcerative colitis and Crohn's disease after completing its Phase I program.

Sep 27, 2026marketbeat.com
Palisade Bio Expands Global Phase 2b ASCENTRA-UC Program with Health Canada CTA Clearance

Canadian clearance supports site activation and enrollment in the global study of once-daily oral PALI-2108 Primary efficacy results from approximately 204 patients with moderately to severely active ulcerative colitis expected in the second half of 2027 Denver, CO, Sept. 23, 2026 (GLOBE NEWSWIRE) -- Palisade Bio, Inc. (Nasdaq: PALI) (“Palisade” or the “Company”), a clinical-stage biopharmaceutical company developing next-generation prodrugs for patients living with inflammatory and fibrotic dis…

Sep 23, 2026globenewswire.com
Palisade Bio Receives FDA Clearance of IND for PALI-2108 in Crohn's Disease, Expanding Phase 2 Development Across IBD

ASCENTRA-CD expected to enroll approximately 60 patients with moderate to severe Crohn's disease First patient dosing targeted for Q1 2027; primary efficacy readout (Week 12 endoscopic response) targeted for Q1 2028 Phase 2 program builds on clinical experience in fibrostenotic Crohn's disease demonstrating targeted tissue exposure, PDE4 target engagement and encouraging endoscopic activity Denver, CO, Sept. 22, 2026 (GLOBE NEWSWIRE) -- Palisade Bio, Inc. (Nasdaq: PALI) (“Palisade” or the “Compa…

Sep 22, 2026globenewswire.com
Palisade Bio to Present at Stifel 2026 Virtual Immunology and Inflammation Forum

Presentation scheduled for September 23, 2026 at 1:00 PM ET Access the webcast here Denver, CO, Sept. 21, 2026 (GLOBE NEWSWIRE) -- Palisade Bio, Inc. (Nasdaq: PALI) (“Palisade” or the “Company”), a clinical-stage biopharmaceutical company developing next-generation prodrugs for patients living with inflammatory and fibrotic diseases, today announced that JD Finley, Chief Executive Officer, and Mitchell Jones, M.D.

Sep 21, 2026globenewswire.com
Palisade Bio, Inc. (PALI) Presents at Morgan Stanley 24th Annual Global Healthcare Conference Transcript

Palisade Bio, Inc. (PALI) Presents at Morgan Stanley 24th Annual Global Healthcare Conference Transcript

Sep 16, 2026seekingalpha.com
Palisade Bio to Participate in Upcoming Investor Conferences

Denver, CO, Sept. 03, 2026 (GLOBE NEWSWIRE) -- Palisade Bio, Inc. (Nasdaq: PALI) (“Palisade” or the “Company”), a clinical-stage biopharmaceutical company developing next-generation prodrugs for patients living with inflammatory and fibrotic diseases, today announced that members of management will participate in three healthcare investor conferences in September 2026.

Sep 3, 2026globenewswire.com
Brokerages Set Palisade Bio, Inc. (NASDAQ:PALI) Price Target at $9.00

Palisade Bio, Inc. (NASDAQ: PALI - Get Free Report) has received a consensus rating of "Buy" from the ten ratings firms that are covering the firm, Marketbeat Ratings reports. One research analyst has rated the stock with a sell recommendation, seven have assigned a buy recommendation and two have given a strong buy recommendation to the

Aug 17, 2026defenseworld.net
Palisade Bio Reports Second Quarter 2026 Financial Results and Highlights Continued Advancement of PALI-2108 Into Phase 2 Development

Advancing a potentially best-in-class once-daily oral, locally-activated PDE4 inhibitor prodrug specifically engineered for the treatment of inflammatory bowel disease (IBD) Enrollment of first patient for Phase 2 ASCENTRA-UC trial of PALI-2108 expected in the second half of 2026; primary efficacy results expected in the second half of 2027 IND for Phase 2 ASCENTRA-CD trial of PALI-2108 for the treatment of Crohn's disease expected in the second half of 2026 Strong balance sheet expected to supp…

Aug 10, 2026globenewswire.com