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Spruce Biosciences, Inc.

SPRB
Healthcare|Biotechnology|US
$46.55
+3.84 (+8.99%)
DCF Value
$61.82
Tangible Book / Share
$34.44
Cash / Share
$39.61

About

Spruce Biosciences, Inc., founded in 2014 and situated in Daly City, California, operates as a biopharmaceutical enterprise. Its primary objective is to advance and bring to market innovative treatments, particularly for uncommon endocrine conditions. A central component of its therapeutic pipeline is tildacerfont, a non-steroidal drug candidate. This compound is currently undergoing Phase 2b clinical assessments in adult patients with congenital adrenal hyperplasia (CAH), with the aim of optimizing disease management and lessening dependence on steroid medications by examining reductions in glucocorticoid levels and their clinical consequences. Tildacerfont is also progressing through Phase 2 trials for pediatric classic CAH, as well as investigating its efficacy in women suffering from polycystic ovary syndrome (PCOS). Additionally, Spruce Biosciences maintains a collaborative licensing agreement with Eli Lilly and Company to jointly explore, formulate, and commercialize various pharmaceutical substances.

Stock Price

-61.0%(1Y)
1M
+2.2%
3M
-0.7%
6M
-17.6%
YTD
-46.6%
1Y
-59.7%
3Y
-44.6%
5Y
-86.6%

Pipeline Summary

8 total trials
0
Phase 1
6
Phase 2
1
Phase 3
0
Phase 4
Completed: 2Available: 1Terminated: 4Not Yet Recruiting: 1

Key Facts

Market Cap$133.8M
Employees8 (-62% YoY)
CEOJavier Szwarcberg
IPO DateOct 9, 2020
Beta3.54
52-Week Range$38.06 – $129
Avg Volume76,881
ExchangeNASDAQ

Ownership

Float70.2%
Shares Outstanding2.9M

Recent Insider Trades

Quartel Adrian WAWARD
Jul 27, 202613,000 shares
Quartel Adrian WOTHER
Jul 27, 20260 shares
Szwarcberg Javier B.AWARD
Jun 30, 2026266 shares @ $4.53
SPIEGELMAN DANIEL KAWARD
May 21, 20261,700 shares @ $52.70
SIMPSON CAMILLA VAWARD
May 21, 20261,700 shares @ $52.70

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Data last updated: Nov 9, 2026, 04:35 AM