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Spruce Biosciences, Inc.

SPRB
Healthcare|Biotechnology|US
$46.55
+3.84 (+8.99%)
DCF Value
$61.82
Tangible Book / Share
$34.44
Cash / Share
$39.61

Ownership Breakdown

70.2%
Float
2.9M
Shares Outstanding
2.0M
Float Shares

Major Holders (40)

Combined: 199.0%

Holders of 5%+ from their latest Schedule 13D/13G filing in the last two years. Percentages are as of each filing date.

HolderType% of ClassSharesFiledFiling
Bradley L. RadoffIndividual9.60%3,975,000Nov 12, 202413D/G
AIGH Capital Management LLCIA, OO9.10%250,000Jul 27, 202613D/G
Orin HirschmanHC, IN9.10%250,000Jul 27, 202613D/G
BlackRock, Inc.Holding company6.80%187,836Jul 30, 202613D/G
Boone Peter David MrIndividual6.40%68,184Nov 24, 202513D/G
Israel A. EnglanderIndividual5.80%160,981Aug 4, 202613D/G
Millennium Group Management LLCOther5.80%160,981Aug 4, 202613D/G
Millennium Management LLCOther5.80%160,981Aug 4, 202613D/G
Integrated Core Strategies (US) LLCOther5.80%160,981Aug 4, 202613D/G
AWM Investment Company, Inc.Investment adviser5.10%146,988Aug 14, 202613D/G
Armistice Capital, LLCIA, OO4.99%2,169,245Nov 14, 202413D/G
Steven BoydHC, IN4.99%2,169,245Nov 14, 202413D/G
OrbiMed Advisors LLCInvestment adviser4.80%132,200Aug 14, 202613D/G
Ikarian Capital, LLCInvestment adviser4.80%121,356May 7, 202613D/G
Neil ShahrestaniHC, IN4.80%121,356May 7, 202613D/G
Carlyle Holdings I L.P.Partnership4.70%50,893Feb 18, 202613D/G
CG Subsidiary Holdings L.L.C.Other4.70%50,893Feb 18, 202613D/G
TC Group, L.L.C.Other4.70%50,893Feb 18, 202613D/G
Carlyle Investment Management L.L.C.Other4.70%50,893Feb 18, 202613D/G
Carlyle Genesis UK LLCOther4.70%50,893Feb 18, 202613D/G
Abingworth LLPPartnership4.70%50,893Feb 18, 202613D/G
Abingworth Bioventures VII LPPartnership4.70%50,893Feb 18, 202613D/G
The Carlyle Group Inc.Corporation4.70%50,893Feb 18, 202613D/G
Carlyle Holdings I GP Inc.Corporation4.70%50,893Feb 18, 202613D/G
Carlyle Holdings I GP Sub L.L.C.Other4.70%50,893Feb 18, 202613D/G
Anand ParekhIndividual4.49%61,670May 15, 202613D/G
Alyeska Fund GP, LLCOther4.49%61,670May 15, 202613D/G
Alyeska Investment Group, L.P.Investment adviser4.49%61,670May 15, 202613D/G
John P. McKearn, Ph.D.Individual4.20%1,759,521Jan 10, 202513D/G
Jay SchmelterIndividual4.20%1,759,521Jan 10, 202513D/G
5AM Opportunities II (GP), LLCOther4.10%1,773,000Nov 14, 202413D/G
Andrew J. SchwabIndividual4.10%1,773,000Nov 14, 202413D/G
5AM Opportunities II, L.P.Partnership4.10%1,773,000Nov 14, 202413D/G
Dr. Kush ParmarIndividual4.10%1,773,000Nov 14, 202413D/G
Wellington Investment Advisors Holdings LLPHolding company3.60%48,796May 15, 202613D/G
Wellington Group Holdings LLPHolding company3.60%48,796May 15, 202613D/G
Wellington Management Group LLPHolding company3.60%48,796May 15, 202613D/G
HealthCap VIII, L.P.Partnership3.40%36,640Oct 9, 202513D/G
HealthCap VIII GP LLCPartnership3.40%36,640Oct 9, 202513D/G
OrbiMed Capital LLCInvestment adviser2.50%67,800Aug 14, 202613D/G

Insider Trades (100)

Last 4 quarters: 126,607 acquired · 52,257 disposed
InsiderPositionDateTypeSharesPriceValueFiling
Quartel Adrian WChief Medical OfficerJul 27, 2026AWARD13,000——Form 4
Quartel Adrian WJul 27, 2026OTHER0——Form 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICERJun 30, 2026AWARD266$4.53$1.2KForm 4
SPIEGELMAN DANIEL KdirectorMay 21, 2026AWARD1,700$52.70$89.6KForm 4
SIMPSON CAMILLA VdirectorMay 21, 2026AWARD1,700$52.70$89.6KForm 4
GREY MICHAEL Gdirector, officer: Executive ChairmanMay 21, 2026AWARD1,700$52.70$89.6KForm 4
Barretto-Ko PercivaldirectorMay 21, 2026AWARD1,700$52.70$89.6KForm 4
Walbert KelidirectorMay 21, 2026AWARD1,700$52.70$89.6KForm 4
Hooks Corwin DaleChief Commercial OfficerMar 9, 2026AWARD11,000——Form 4
Hooks Corwin DaleMar 9, 2026OTHER0——Form 4
Ways Douglas Kirkdirector, officer: Interim Chief Medical OfficerDec 11, 2025AWARD5,000——Form 4
Ways Douglas Kirkdirector, officer: Interim Chief Medical OfficerDec 11, 2025OPTION EX.1,250——Form 4
Ways Douglas Kirkdirector, officer: Interim Chief Medical OfficerDec 11, 2025OPTION EX.1,250——Form 4
Ways Douglas Kirkdirector, officer: Interim Chief Medical OfficerDec 11, 2025AWARD400$104.13$41.7KForm 4
Ways Douglas Kirkdirector, officer: Interim Chief Medical OfficerDec 11, 2025AWARD266$104.13$27.7KForm 4
Ways Douglas Kirkdirector, officer: Interim Chief Medical OfficerDec 11, 2025DISPOSED266$791.25$210.5KForm 4
Ways Douglas Kirkdirector, officer: Interim Chief Medical OfficerDec 11, 2025DISPOSED400$169.50$67.8KForm 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICERDec 31, 2025AWARD4,690$4.53$21.2KForm 4
Gharib Samir M.PRESIDENT AND CFODec 15, 2025OPTION EX.513——Form 4
Gharib Samir M.PRESIDENT AND CFODec 15, 2025TAX W/H184$80.67$14.8KForm 4
Gharib Samir M.PRESIDENT AND CFODec 15, 2025OPTION EX.496——Form 4
Gharib Samir M.PRESIDENT AND CFODec 15, 2025TAX W/H178$80.67$14.4KForm 4
Gharib Samir M.PRESIDENT AND CFODec 15, 2025OPTION EX.513——Form 4
Gharib Samir M.PRESIDENT AND CFODec 15, 2025OPTION EX.496——Form 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICERDec 15, 2025OPTION EX.1,196——Form 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICERDec 15, 2025OPTION EX.1,480——Form 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICERDec 15, 2025TAX W/H608$80.67$49.0KForm 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICERDec 15, 2025TAX W/H752$80.67$60.7KForm 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICERDec 15, 2025OPTION EX.1,196——Form 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICERDec 11, 2025AWARD1,666$104.13$173.5KForm 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICERDec 15, 2025OPTION EX.1,480——Form 4
SPIEGELMAN DANIEL KdirectorDec 11, 2025AWARD458$104.13$47.7KForm 4
SPIEGELMAN DANIEL KdirectorDec 11, 2025AWARD400$104.13$41.7KForm 4
SPIEGELMAN DANIEL KdirectorDec 11, 2025AWARD88$104.13$9.2KForm 4
SPIEGELMAN DANIEL KdirectorDec 11, 2025DISPOSED88$1143.00$100.6KForm 4
SPIEGELMAN DANIEL KdirectorDec 11, 2025DISPOSED400$169.50$67.8KForm 4
SPIEGELMAN DANIEL KdirectorDec 11, 2025DISPOSED458$564.00$258.3KForm 4
GREY MICHAEL Gdirector, officer: Executive ChairmanDec 11, 2025AWARD1,499$104.13$156.1KForm 4
GREY MICHAEL Gdirector, officer: Executive ChairmanDec 11, 2025AWARD1,255$104.13$130.7KForm 4
GREY MICHAEL Gdirector, officer: Executive ChairmanDec 11, 2025AWARD666$104.13$69.4KForm 4
GREY MICHAEL Gdirector, officer: Executive ChairmanDec 11, 2025AWARD400$104.13$41.7KForm 4
GREY MICHAEL Gdirector, officer: Executive ChairmanDec 11, 2025AWARD387$104.13$40.3KForm 4
GREY MICHAEL Gdirector, officer: Executive ChairmanDec 11, 2025AWARD133$104.13$13.8KForm 4
GREY MICHAEL Gdirector, officer: Executive ChairmanDec 11, 2025DISPOSED387$108.00$41.8KForm 4
GREY MICHAEL Gdirector, officer: Executive ChairmanDec 11, 2025DISPOSED1,255$123.00$154.4KForm 4
GREY MICHAEL Gdirector, officer: Executive ChairmanDec 11, 2025DISPOSED1,499$230.25$345.1KForm 4
GREY MICHAEL Gdirector, officer: Executive ChairmanDec 11, 2025DISPOSED133$1143.00$152.0KForm 4
GREY MICHAEL Gdirector, officer: Executive ChairmanDec 11, 2025DISPOSED666$186.00$123.9KForm 4
GREY MICHAEL Gdirector, officer: Executive ChairmanDec 11, 2025DISPOSED400$169.50$67.8KForm 4
Gharib Samir M.PRESIDENT AND CFODec 11, 2025AWARD1,933$104.13$201.3KForm 4
Gharib Samir M.PRESIDENT AND CFODec 11, 2025AWARD1,579$104.13$164.4KForm 4
Gharib Samir M.PRESIDENT AND CFODec 11, 2025AWARD953$104.13$99.2KForm 4
Gharib Samir M.PRESIDENT AND CFODec 11, 2025AWARD933$104.13$97.2KForm 4
Gharib Samir M.PRESIDENT AND CFODec 11, 2025AWARD733$104.13$76.3KForm 4
Gharib Samir M.PRESIDENT AND CFODec 11, 2025DISPOSED733$1506.00$1.1MForm 4
Gharib Samir M.PRESIDENT AND CFODec 11, 2025DISPOSED1,579$123.00$194.2KForm 4
Gharib Samir M.PRESIDENT AND CFODec 11, 2025DISPOSED933$344.25$321.2KForm 4
Gharib Samir M.PRESIDENT AND CFODec 11, 2025DISPOSED1,933$186.00$359.5KForm 4
Gharib Samir M.PRESIDENT AND CFODec 11, 2025DISPOSED953$230.25$219.4KForm 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICERDec 11, 2025AWARD10,000$104.13$1.0MForm 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICERDec 11, 2025DISPOSED10,000$344.25$3.4MForm 4
SIMPSON CAMILLA VdirectorDec 11, 2025AWARD400$104.13$41.7KForm 4
SIMPSON CAMILLA VdirectorDec 11, 2025AWARD362$104.13$37.7KForm 4
SIMPSON CAMILLA VdirectorDec 11, 2025AWARD309$104.13$32.2KForm 4
SIMPSON CAMILLA VdirectorDec 11, 2025AWARD173$104.13$18.0KForm 4
SIMPSON CAMILLA VdirectorDec 11, 2025AWARD133$104.13$13.8KForm 4
SIMPSON CAMILLA VdirectorDec 11, 2025DISPOSED362$230.25$83.4KForm 4
SIMPSON CAMILLA VdirectorDec 11, 2025DISPOSED400$169.50$67.8KForm 4
SIMPSON CAMILLA VdirectorDec 11, 2025DISPOSED133$1143.00$152.0KForm 4
SIMPSON CAMILLA VdirectorDec 11, 2025DISPOSED309$123.00$38.0KForm 4
SIMPSON CAMILLA VdirectorDec 11, 2025DISPOSED173$108.00$18.7KForm 4
Barretto-Ko PercivaldirectorDec 11, 2025AWARD800$104.13$83.3KForm 4
Barretto-Ko PercivaldirectorDec 11, 2025DISPOSED800$169.50$135.6KForm 4
Walbert KelidirectorDec 11, 2025AWARD3,400$88.41$300.6KForm 4
Walbert KeliDec 11, 2025OTHER0——Form 4
Gharib Samir M.PRESIDENT AND CFODec 11, 2025OPTION EX.1,900——Form 4
Gharib Samir M.PRESIDENT AND CFODec 11, 2025TAX W/H680$88.41$60.1KForm 4
Gharib Samir M.PRESIDENT AND CFODec 11, 2025AWARD7,600——Form 4
Gharib Samir M.PRESIDENT AND CFODec 10, 2025OPTION EX.514——Form 4
Gharib Samir M.PRESIDENT AND CFODec 10, 2025TAX W/H184$85.67$15.8KForm 4
Gharib Samir M.PRESIDENT AND CFODec 11, 2025OPTION EX.1,900——Form 4
Gharib Samir M.PRESIDENT AND CFODec 10, 2025OPTION EX.514——Form 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICERDec 11, 2025AWARD19,800——Form 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICERDec 11, 2025OPTION EX.4,950——Form 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICERDec 11, 2025OPTION EX.4,950——Form 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICERDec 11, 2025TAX W/H2,194$88.41$194.0KForm 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICERDec 10, 2025OPTION EX.1,196——Form 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICERDec 10, 2025TAX W/H428$85.67$36.7KForm 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICERDec 10, 2025OPTION EX.1,196——Form 4
Gharib Samir M.PRESIDENT AND CFOOct 20, 2025OPTION EX.2,053——Form 4
Gharib Samir M.PRESIDENT AND CFOOct 20, 2025TAX W/H661$148.16$97.9KForm 4
Gharib Samir M.PRESIDENT AND CFOOct 20, 2025AWARD2,053——Form 4
Gharib Samir M.PRESIDENT AND CFOOct 20, 2025OPTION EX.2,053——Form 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICEROct 20, 2025OPTION EX.4,784——Form 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICEROct 20, 2025TAX W/H1,539$148.16$228.0KForm 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICEROct 20, 2025AWARD4,784——Form 4
Szwarcberg Javier B.director, officer: CHIEF EXECUTIVE OFFICEROct 20, 2025OPTION EX.4,784——Form 4
Parkman Healthcare Partners LLC10 percent ownerOct 6, 2025BUY256$17.91$4.6KForm 4
Parkman Healthcare Partners LLC10 percent ownerOct 6, 2025SELL232$19.33$4.5KForm 4
Parkman Healthcare Partners LLC10 percent ownerOct 6, 2025SELL25$17.46$436.39Form 4