SPRO logo

Spero Therapeutics, Inc.

SPRO
Healthcare|Biotechnology|US
$1.03
+0.01 (+0.98%)
Tangible Book / Share
$0.76
Graham Number
$1.48
Cash / Share
$0.88

Ownership Breakdown

80.9%
Float
58.2M
Shares Outstanding
47.1M
Float Shares

Major Holders (7)

Combined: 33.8%

Holders of 5%+ from their latest Schedule 13D/13G filing in the last two years. Percentages are as of each filing date.

HolderType% of ClassSharesFiledFiling
GSK PLCCorporation16.40%9,190,606Mar 28, 202513D/G
Amin NathooHC, IN2.90%1,615,469Aug 14, 202513D/G
Anson Funds Management LPIA, PN2.90%1,615,469Aug 14, 202513D/G
Anson Management GP LLCHC, OO2.90%1,615,469Aug 14, 202513D/G
Anson Advisors Inc.FI, CO2.90%1,615,469Aug 14, 202513D/G
Tony MooreHC, IN2.90%1,615,469Aug 14, 202513D/G
Moez KassamHC, IN2.90%1,615,469Aug 14, 202513D/G

Insider Trades (100)

Last 4 quarters: 1,162,000 acquired · 245,374 disposed
InsiderPositionDateTypeSharesPriceValueFiling
Zack DebraChief Medical OfficerAug 3, 2026AWARD324,675$1.54$500.0KForm 4
Zack DebraChief Medical OfficerAug 3, 2026AWARD162,311——Form 4
Zack DebraAug 3, 2026OTHER0——Form 4
Deshpande MilinddirectorJun 23, 2026AWARD10,000——Form 4
Deshpande MilinddirectorJun 23, 2026AWARD20,000$2.15$43.0KForm 4
Tregoning KathleendirectorJun 23, 2026AWARD10,000——Form 4
Tregoning KathleendirectorJun 23, 2026AWARD20,000$2.15$43.0KForm 4
Smith CynthiadirectorJun 23, 2026AWARD10,000——Form 4
Smith CynthiadirectorJun 23, 2026AWARD20,000$2.15$43.0KForm 4
VINK PATRICK V.J.J.directorJun 23, 2026AWARD10,000——Form 4
VINK PATRICK V.J.J.directorJun 23, 2026AWARD20,000$2.15$43.0KForm 4
THOMAS FRANK EdirectorJun 23, 2026AWARD10,000——Form 4
THOMAS FRANK EdirectorJun 23, 2026AWARD20,000$2.15$43.0KForm 4
Jackson Scott ThomasdirectorJun 23, 2026AWARD10,000——Form 4
Jackson Scott ThomasdirectorJun 23, 2026AWARD20,000$2.15$43.0KForm 4
Pottage John C JrdirectorJun 23, 2026AWARD10,000——Form 4
Pottage John C JrdirectorJun 23, 2026AWARD20,000$2.15$43.0KForm 4
Rajavelu EstherSee RemarksMay 4, 2026SELL25,240$2.51$63.4KForm 4
Rajavelu EstherSee RemarksFeb 6, 2026SELL37,101$2.36$87.6KForm 4
Rajavelu EstherSee RemarksFeb 6, 2026SELL50,816$2.36$119.9KForm 4
Keutzer TimothyChief Operating OfficerFeb 6, 2026SELL18,652$2.36$44.0KForm 4
Keutzer TimothyChief Operating OfficerFeb 2, 2026AWARD68,000——Form 4
Keutzer TimothyChief Operating OfficerFeb 2, 2026SELL18,891$2.20$41.6KForm 4
Keutzer TimothyChief Operating OfficerFeb 3, 2026SELL24,224$2.14$51.8KForm 4
Keutzer TimothyChief Operating OfficerFeb 4, 2026SELL3,471$2.24$7.8KForm 4
Keutzer TimothyChief Operating OfficerFeb 2, 2026AWARD137,000$2.23$305.5KForm 4
Rajavelu EstherSee RemarksFeb 2, 2026AWARD249,000——Form 4
Rajavelu EstherSee RemarksFeb 2, 2026SELL18,442$2.20$40.6KForm 4
Rajavelu EstherSee RemarksFeb 2, 2026AWARD498,000$2.23$1.1MForm 4
Rajavelu EstherSee RemarksNov 7, 2025SELL40,270$2.37$95.4KForm 4
Mahadevia AnkitdirectorAug 28, 2025SELL6,572$1.97$12.9KForm 4
Keutzer TimothyChief Operating OfficerAug 28, 2025SELL1,695$1.97$3.3KForm 4
Mahadevia AnkitdirectorJun 12, 2025AWARD20,000——Form 4
Deshpande MilinddirectorJun 12, 2025AWARD20,000——Form 4
Jackson Scott ThomasdirectorJun 12, 2025AWARD20,000——Form 4
VINK PATRICK V.J.J.directorJun 12, 2025AWARD20,000——Form 4
Pottage John C JrdirectorJun 12, 2025AWARD20,000——Form 4
Smith CynthiadirectorJun 12, 2025AWARD20,000——Form 4
THOMAS FRANK EdirectorJun 12, 2025AWARD20,000——Form 4
Tregoning KathleendirectorJun 12, 2025AWARD20,000——Form 4
Rajavelu EstherSee RemarksMay 2, 2025AWARD185,000——Form 4
Keutzer TimothyChief Operating OfficerFeb 3, 2025AWARD266,139——Form 4
Keutzer TimothyChief Operating OfficerFeb 5, 2025SELL3,974$0.78$3.1KForm 4
Keutzer TimothyChief Operating OfficerFeb 5, 2025SELL27,643$0.78$21.6KForm 4
Keutzer TimothyChief Operating OfficerFeb 5, 2025SELL24,920$0.78$19.4KForm 4
Rajavelu EstherCFO & CBOFeb 3, 2025AWARD100,000——Form 4
Rajavelu EstherCFO & CBOFeb 5, 2025SELL20,689$0.78$16.1KForm 4
Rajavelu EstherCFO & CBOFeb 3, 2025AWARD266,139——Form 4
Shukla SathCEO & PresidentFeb 3, 2025AWARD751,407——Form 4
Shukla SathCEO & PresidentFeb 5, 2025SELL6,139$0.78$4.8KForm 4
Shukla SathCEO & PresidentFeb 5, 2025SELL42,786$0.78$33.4KForm 4
Shukla SathCEO & PresidentFeb 5, 2025SELL106,408$0.78$83.0KForm 4
Mahadevia AnkitdirectorFeb 5, 2025SELL13,959$0.78$10.9KForm 4
Mahadevia AnkitdirectorFeb 5, 2025SELL55,260$0.78$43.1KForm 4
Rajavelu EstherCFO & CBONov 7, 2024SELL23,351$1.31$30.6KForm 4
Rajavelu EstherCFO & CBONov 8, 2024SELL17,245$1.30$22.4KForm 4
Mahadevia AnkitdirectorAug 27, 2024SELL5,912$1.35$8.0KForm 4
Keutzer TimothyChief Operating OfficerAug 27, 2024SELL2,213$1.35$3.0KForm 4
Shukla SathCEO & PresidentAug 27, 2024SELL2,757$1.35$3.7KForm 4
Shukla SathCEO and PresidentAug 2, 2024SELL14,800$1.32$19.5KForm 4
Shukla SathCEO and PresidentAug 5, 2024SELL17,641$1.31$23.1KForm 4
Deshpande MilinddirectorMay 29, 2024AWARD20,000——Form 4
Jackson Scott ThomasdirectorMay 29, 2024AWARD20,000——Form 4
Mahadevia AnkitdirectorMay 29, 2024AWARD20,000——Form 4
VINK PATRICK V.J.J.directorMay 29, 2024AWARD20,000——Form 4
Tregoning KathleendirectorMay 29, 2024AWARD20,000——Form 4
Smith CynthiadirectorMay 29, 2024AWARD20,000——Form 4
THOMAS FRANK EdirectorMay 29, 2024AWARD20,000——Form 4
Pottage John C JrdirectorMay 29, 2024AWARD20,000——Form 4
Keutzer TimothyChief Operating OfficerFeb 1, 2024AWARD239,731——Form 4
Keutzer TimothyChief Operating OfficerFeb 2, 2024SELL30,971$1.36$42.1KForm 4
Mahadevia AnkitdirectorFeb 2, 2024SELL63,795$1.37$87.4KForm 4
JOSEPH TAMARA LChief Legal OfficerFeb 1, 2024AWARD239,731——Form 4
JOSEPH TAMARA LChief Legal OfficerFeb 2, 2024SELL30,906$1.37$42.3KForm 4
HAMED KAMALChief Medical OfficerFeb 1, 2024AWARD239,731——Form 4
HAMED KAMALChief Medical OfficerFeb 2, 2024SELL28,075$1.37$38.5KForm 4
Rajavelu EstherSee RemarksFeb 1, 2024AWARD119,866——Form 4
Shukla Sathdirector, officer: CEO and PresidentFeb 1, 2024AWARD679,501——Form 4
Shukla Sathdirector, officer: CEO and PresidentFeb 2, 2024SELL30,901$1.37$42.3KForm 4
Shukla Sathdirector, officer: CEO and PresidentFeb 5, 2024SELL45,093$1.45$65.4KForm 4
Tregoning KathleendirectorJan 2, 2024AWARD35,604$1.52$54.1KForm 4
Rajavelu EstherSee RemarksNov 13, 2023AWARD300,000——Form 4
Rajavelu EstherNov 6, 2023OTHER0——Form 4
Pottage John C JrdirectorOct 5, 2023AWARD20,000——Form 4
Smith CynthiadirectorOct 5, 2023AWARD20,000——Form 4
THOMAS FRANK EdirectorOct 5, 2023AWARD20,000——Form 4
Deshpande MilinddirectorOct 5, 2023AWARD20,000——Form 4
Tregoning KathleendirectorOct 5, 2023AWARD20,000——Form 4
VINK PATRICK V.J.J.directorOct 5, 2023AWARD20,000——Form 4
Jackson Scott ThomasdirectorOct 5, 2023AWARD20,000——Form 4
Mahadevia AnkitdirectorOct 5, 2023AWARD20,000——Form 4
HAMED KAMALChief Medical OfficerSep 13, 2023SELL39,496$1.27$50.2KForm 4
Keutzer TimothyChief Development OfficerAug 28, 2023SELL1,854$1.26$2.3KForm 4
JOSEPH TAMARA LChief Legal OfficerAug 28, 2023SELL1,854$1.26$2.3KForm 4
Mahadevia AnkitdirectorAug 28, 2023SELL9,040$1.26$11.4KForm 4
Shukla Sathdirector, officer: CEO and PresidentAug 28, 2023SELL1,854$1.26$2.3KForm 4
Shukla Sathdirector, officer: CEO and PresidentAug 29, 2023SELL4,163$1.30$5.4KForm 4
Shukla Sathdirector, officer: CEO and PresidentAug 1, 2023AWARD266,000——Form 4
DiPalma Stephen J.Jul 15, 2023OTHER0——Form 4
HAMED KAMALChief Medical OfficerJun 12, 2023AWARD140,000——Form 4