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TScan Therapeutics, Inc.

TCRX
Healthcare|Biotechnology|US
$0.19
+0.01 (+3.41%)
Tangible Book / Share
$0.53
Cash / Share
$0.77

About

TScan Therapeutics, Inc., a clinical-stage biotechnology company, develops T cell receptor-engineered T cell (TCR-T) therapies for the treatment of patients with cancer in the United States. The company’s lead product is TSC-101, for the treatment of patients with acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), and acute lymphoblastic leukemia (ALL) in patients undergoing allogeneic hematopoietic cell transplantation (HCT), which is in Phase I clinical trial, as well as eliminates residual disease and promotes donor chimerism. It also develops TSC-102-A01 and TSC-102-A03, which are allogeneic and donor-derived TCR-T therapy candidates targeting epitopes. In addition, the company develops TSC-200, TSC-201, TSC-202, TSC-203, and TSC-204 for the treatment of solid tumors. It has a research collaboration and license agreement with Amgen Inc. to identify antigens recognized by T cells in patients with Crohn’s disease. TScan Therapeutics, Inc. was incorporated in 2018 and is headquartered in Waltham, Massachusetts.

Stock Price

-83.8%(1Y)
1M
-17.6%
3M
-76.4%
6M
-85.1%
YTD
-81.2%
1Y
-82.8%
3Y
-95.7%
5Y
-97.8%

Pipeline Summary

9 total trials
2
Phase 1
0
Phase 2
1
Phase 3
0
Phase 4
Active: 4Completed: 3Withdrawn: 1Recruiting: 1

Active Trials (5)

A Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation
NCT07702578AML
Phase 3Active
Enrollment: 310 participants
A Screening Study to Collect Samples for TAA, HLA & HLA Loss of Heterozygosity in Patients With Metastatic Solid Tumors
NCT05812027Head and Neck Cancer
Active
Enrollment: 1,150 participants
A Basket Study of Customized Autologous TCR-T Cell Therapies in Patients With Locally Advanced (Unresectable) or Metastatic Solid Tumors
NCT05973487Head and Neck Cancer
Phase 1Active
Enrollment: 840 participants
A Study of T-Cell Receptor Engineered Donor T Cells in Subjects Undergoing Allogeneic Peripheral Blood Stem Cell Transplantation (ALLOHA)
NCT05473910AML
Phase 1Active
Enrollment: 310 participants
A Long Term Follow-up Study of TScan TCR-T Products
NCT06976736AML
Recruiting
Enrollment: 1,000 participants

Key Facts

Market Cap$11.9M
Employees142 (-27% YoY)
CEOGavin MacBeath
IPO DateJul 16, 2021
Beta1.19
52-Week Range$0.171 – $1.47
Avg Volume739,764
ExchangeNASDAQ
Websitetscan.com

Ownership

Float85.6%
Shares Outstanding63.5M

Recent Insider Trades

MacBeath GavinAWARD
Oct 1, 20261,000,000 shares
ZDRAVESKI ZORANAWARD
Oct 1, 2026300,000 shares
BAKER BROS. ADVISORS LPAWARD
May 20, 202667,000 shares @ $0.99
Woods KeithAWARD
May 20, 202667,000 shares @ $0.99
Nicholson Garry AAWARD
May 20, 202667,000 shares @ $0.99

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Data last updated: Nov 9, 2026, 04:36 AM