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Prelude Therapeutics Incorporated

PRLD
Healthcare|Biotechnology|US
$3.60
+0.04 (+1.27%)
DCF Value
$3.79
Tangible Book / Share
$1.36
Cash / Share
$1.54

About

Prelude Therapeutics, Inc. is a clinical-stage precision oncology company focused on identifying and developing innovative, targeted cancer treatments for patient populations with unmet medical needs. Its pipeline includes PRT543, currently undergoing Phase 1 clinical evaluation for certain solid tumors and myeloid malignancies. Another asset, PRT811, is also in Phase 1 trials, targeting various solid tumors, notably glioblastoma multiforme. The company is additionally progressing PRT1419, a potent and selective inhibitor of the anti-apoptotic protein; PRT2527, a powerful and highly kinome-selective CDK9 inhibitor; PRT-SCA2, which is in preclinical development for several genomically selected cancers; PRT3645, a brain-penetrant molecule that precisely and effectively targets CDK4/6; and PRT-K4, another preclinical compound for solid tumors. Founded in 2016, the firm's headquarters are located in Wilmington, Delaware.

Stock Price

+166.7%(1Y)
1M
-7.2%
3M
-26.5%
6M
-25.9%
YTD
+24.1%
1Y
+185.7%
3Y
+20.0%
5Y
-79.3%

Pipeline Summary

13 total trials
12
Phase 1
1
Phase 2
0
Phase 3
0
Phase 4
Completed: 8Terminated: 3Not Yet Recruiting: 1Recruiting: 1

Active Trials (1)

A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative Neoplasms
NCT07469891Polycythemia Vera (PV)
Phase 1Recruiting
Enrollment: 100 participants

Key Facts

Market Cap$208.4M
Employees79 (-40% YoY)
CEOKrishna Vaddi
IPO DateSep 25, 2020
Beta0.96
52-Week Range$1.17 – $6.83
Avg Volume449,545
ExchangeNASDAQ

Ownership

Float56.0%
Shares Outstanding79.8M

Recent Insider Trades

BAKER BROS. ADVISORS LPAWARD
Jun 9, 202638,000 shares @ $3.94
Dorton KatinaAWARD
Jun 9, 202638,000 shares @ $3.94
Babler MartinAWARD
Jun 9, 202638,000 shares @ $3.94
Bonita David PAWARD
Jun 9, 202638,000 shares @ $3.94
Sandor VictorAWARD
Jun 9, 202638,000 shares @ $3.94

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Data last updated: Nov 9, 2026, 04:29 AM