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Prelude Therapeutics Incorporated

PRLD
Healthcare|Biotechnology|US
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Clinical Trials (13)

TrialConditionsPhaseStatusEnrollmentDesignDrug
NCT07469891
A Phase 1 Study of PRT12396 in Participants With Select Myeloproliferative Neoplasms
Polycythemia Vera (PV), Myelofibrosis (MF)
P1
Recruiting100Open-labelPRT12396
NCT06682806
A Study of PRT3789 in Combination With Pembrolizumab in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation
Advanced Solid Tumor, Esophageal Cancer
P2
Terminated6Open-labelPRT3789, pembrolizumab
NCT05159518
A Study of PRT2527 in Participants With Advanced Solid Tumors
Sarcoma, Castrate Resistant Prostate Cancer
P1
Completed30Open-labelPRT2527
NCT05665530
A Study of PRT2527 as Monotherapy and in Combination With Zanubrutinib or Venetoclax in Participants With R/R Hematologic Malignancies
Aggressive B-Cell Non-Hodgkin's Lymphoma (NHL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)
P1
Completed86Open-labelPRT2527, Zanubrutinib, Venetoclax
NCT05107856
PRT1419 as Monotherapy or in Combination With Azacitidine or Venetoclax in R/R Myeloid or B-cell Malignancies
Acute Myeloid Leukemia, B-cell Non-Hodgkin Lymphoma
P1
Terminated21Open-labelPRT1419, Azacitidine, Venetoclax
NCT03886831
A Study of PRT543 in Participants With Advanced Solid Tumors and Hematologic Malignancies
Relapsed/Refractory Advanced Solid Tumors, Relapsed/Refractory Diffuse Large B-cell Lymphoma
P1
Completed232Open-labelPRT543
NCT05639751
PRT3789 Monotherapy and in Combo w/Docetaxel in Participants w/Advanced or Metastatic Solid Tumors w/SMARCA4 Mutation
Advanced Solid Tumor, Metastatic Solid Tumor
P1
Completed135Open-labelPRT3789, Docetaxel
NCT04089449
A Study of PRT811 in Participants With Advanced Solid Tumors, CNS Lymphoma and Gliomas
Advanced Solid Tumor, Recurrent Glioma
P1
Completed86Open-labelPRT811
NCT06560645
A Study of PRT7732, an Oral SMARCA2 Degrader, in Patients With Advanced or Metastatic Solid Tumors With a SMARCA4 Mutation
Advanced Solid Tumor, Metastatic Solid Tumor
P1
Terminated42Open-labelPRT7732
NCT04837677
A Study of PRT1419 in Patients With Advanced Solid Tumors
Sarcoma, Melanoma
P1
Completed26Open-labelPRT1419
NCT07905001
A Phase 1/1b Study of PRT13722 in Participants With Advanced HR+/HER2- Breast Cancer
Breast Cancer, Hormone-receptor-positive Breast Cancer
P1
Not Yet Recruiting242Open-labelPRT13722, Fulvestrant, Abemaciclib, Imlunestrant
NCT05538572
A Study of PRT3645 in Participants With Select Advanced or Metastatic Solid Tumors
Breast Cancer, Glioblastoma
P1
Completed22Open-labelPRT3645
NCT04543305
A Study of PRT1419 in Patients With Relapsed/Refractory Hematologic Malignancies
Multiple Myeloma, Acute Myeloid Leukemia
P1
Completed16Open-labelPRT1419