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Prelude Therapeutics Incorporated

PRLD
Healthcare|Biotechnology|US
$3.60
+0.04 (+1.27%)
DCF Value
$3.79
Tangible Book / Share
$1.36
Cash / Share
$1.54

Ownership Breakdown

56.0%
Float
79.8M
Shares Outstanding
44.7M
Float Shares

Major Holders (23)

Combined: 188.8%

Holders of 5%+ from their latest Schedule 13D/13G filing in the last two years. Percentages are as of each filing date.

HolderType% of ClassSharesFiledFiling
Orbimed Advisors LLCInvestment adviser16.00%12,935,071Apr 23, 202613D/G
Baker Bros. Advisors (GP) LLCHC, OO15.50%10,295,301Apr 22, 202613D/G
Felix J. BakerHC, IN15.50%10,295,301Apr 22, 202613D/G
Julian C. BakerHC, IN15.50%10,295,301Apr 22, 202613D/G
Baker Bros. Advisors LPIA, PN15.50%10,295,301Apr 22, 202613D/G
Orbimed Capital GP VI LLCOther14.60%11,808,945Apr 23, 202613D/G
Vaddi KrishnaIndividual13.15%6,745,647Feb 13, 202613D/G
Rajeev ShahHC, IN9.90%6,477,309Apr 28, 202613D/G
RA Capital Management, L.P.IA, PN9.90%6,477,309Apr 28, 202613D/G
Peter KolchinskyHC, IN9.90%6,477,309Apr 28, 202613D/G
RA Capital Healthcare Fund, L.P.Partnership9.90%6,477,309Apr 28, 202613D/G
Incyte CorpCorporation9.90%4,372,124Nov 7, 202513D/G
Levy GuyIndividual5.20%3,378,378Jul 8, 202613D/G
Soleus GP, LLCOther5.20%3,378,378Jul 8, 202613D/G
Soleus Capital Management, L.P.Partnership5.20%3,378,378Jul 8, 202613D/G
Soleus Capital Group, LLCOther4.20%2,702,702Jul 8, 202613D/G
Soleus Capital, LLCOther4.20%2,702,702Jul 8, 202613D/G
Soleus Capital Master Fund, L.P.Non-US institution4.20%2,702,702Jul 8, 202613D/G
OrbiMed Genesis GP LLCOther1.40%1,126,126Apr 23, 202613D/G
Soleus Private Equity Fund III, L.P.Partnership1.00%675,676Jul 8, 202613D/G
Soleus Private Equity GP III, LLCOther1.00%675,676Jul 8, 202613D/G
Soleus PE GP III, LLCOther1.00%675,676Jul 8, 202613D/G
Orbimed Capital LLCInvestment adviser1.00%789,500Apr 23, 202613D/G

Insider Trades (100)

Last 4 quarters: 11,679,917 acquired · 1,432,460 disposed
InsiderPositionDateTypeSharesPriceValueFiling
BAKER BROS. ADVISORS LPdirector, 10 percent owner: Jun 9, 2026AWARD38,000$3.94$149.7KForm 4
Dorton KatinadirectorJun 9, 2026AWARD38,000$3.94$149.7KForm 4
Babler MartindirectorJun 9, 2026AWARD38,000$3.94$149.7KForm 4
Bonita David Pdirector, 10 percent owner: Jun 9, 2026AWARD38,000$3.94$149.7KForm 4
Sandor VictordirectorJun 9, 2026AWARD38,000$3.94$149.7KForm 4
FRIEDMAN PAUL AdirectorJun 9, 2026AWARD38,000$3.94$149.7KForm 4
Morris Charles QChief Medical OfficerMay 1, 2026AWARD450,000$4.70$2.1MForm 4
RA CAPITAL MANAGEMENT, L.P.10 percent ownerApr 27, 2026DISPOSED1,407,000$0.00$140.70Form 4
RA CAPITAL MANAGEMENT, L.P.10 percent ownerApr 27, 2026J1,407,000$0.00$140.70Form 4
RA CAPITAL MANAGEMENT, L.P.10 percent ownerApr 21, 2026OTHER0——Form 4
Bonita David Pdirector, 10 percent owner: Apr 21, 2026BUY1,689,189$4.44$7.5MForm 4
Bonita David Pdirector, 10 percent owner: Apr 21, 2026BUY1,126,126$4.44$5.0MForm 4
ORBIMED ADVISORS LLCdirector, 10 percent owner: Apr 21, 2026BUY1,689,189$4.44$7.5MForm 4
ORBIMED ADVISORS LLCdirector, 10 percent owner: Apr 21, 2026BUY1,126,126$4.44$5.0MForm 4
BAKER BROS. ADVISORS LPdirector, 10 percent owner: Apr 21, 2026BUY2,137,651$0.00$213.77Form 4
BAKER BROS. ADVISORS LPdirector, 10 percent owner: Apr 21, 2026BUY114,601$0.00$11.46Form 4
Morris Charles QApr 15, 2026OTHER0——Form 4
Brusky Sean P.Chief Business OfficerMar 5, 2026OTHER0——Form 4
Brusky Sean P.Chief Business OfficerMar 5, 2026OTHER275,000——Form 4
Combs AndrewChief Chemistry OfficerFeb 4, 2026AWARD230,000$2.30$529.0KForm 4
Scherle PeggyChief Scientific OfficerFeb 4, 2026AWARD230,000$2.30$529.0KForm 4
Lim Bryant DavidCLO, CFO, Corp Sec.Feb 4, 2026AWARD275,000$2.30$632.5KForm 4
Vaddi Krishnadirector, officer: CEOFeb 4, 2026AWARD837,000$2.30$1.9MForm 4
Sandor VictordirectorNov 5, 2025AWARD121,285$1.39$168.6KForm 4
Dorton KatinaOct 17, 2025OTHER0——Form 4
Huang JanePresident, CMOOct 4, 2025OPTION EX.9,375——Form 4
Huang JanePresident, CMOOct 4, 2025TAX W/H3,355$1.47$4.9KForm 4
Huang JanePresident, CMOOct 4, 2025OPTION EX.9,375——Form 4
Huang JanePresident, CMOJul 4, 2025OPTION EX.9,375——Form 4
Huang JanePresident, CMOJul 4, 2025TAX W/H3,355$0.79$2.7KForm 4
Huang JanePresident, CMOJul 4, 2025OPTION EX.9,375——Form 4
BAKER BROS. ADVISORS LPdirector, 10 percent owner: Jun 12, 2025AWARD76,000$1.04$79.0KForm 4
Scherer Paul CJun 12, 2025OTHER0——Form 4
Sandor VictordirectorJun 12, 2025AWARD38,000$1.04$39.5KForm 4
Dier MardidirectorJun 12, 2025AWARD38,000$1.04$39.5KForm 4
FRIEDMAN PAUL AdirectorJun 12, 2025AWARD38,000$1.04$39.5KForm 4
Bonita David Pdirector, 10 percent owner: Jun 12, 2025AWARD38,000$1.04$39.5KForm 4
Babler MartindirectorJun 12, 2025AWARD38,000$1.04$39.5KForm 4
Huang JanePresident, CMOApr 4, 2025OPTION EX.9,375——Form 4
Huang JanePresident, CMOApr 4, 2025TAX W/H3,355$0.68$2.3KForm 4
Huang JanePresident, CMOApr 4, 2025OPTION EX.9,375——Form 4
Combs AndrewChief Chemistry OfficerMar 25, 2025BUY100,000$0.69$69.3KForm 4
Vaddi Krishnadirector, officer: CEOMar 25, 2025BUY675,000$0.69$467.4KForm 4
Vaddi Krishnadirector, officer: CEOMar 21, 2025BUY15,000$0.73$11.0KForm 4
Vaddi Krishnadirector, officer: CEOMar 20, 2025BUY5,416$0.73$4.0KForm 4
Vaddi Krishnadirector, officer: CEOMar 17, 2025BUY9,106$0.75$6.8KForm 4
Vaddi Krishnadirector, officer: CEOMar 14, 2025BUY29,999$0.75$22.6KForm 4
Vaddi Krishnadirector, officer: CEOMar 13, 2025BUY50,000$0.72$35.8KForm 4
Vaddi Krishnadirector, officer: CEOMar 12, 2025BUY47,500$0.71$33.7KForm 4
Lim Bryant DavidCLO, CFO, Corp Sec.Feb 4, 2025AWARD200,000$1.11$222.0KForm 4
Scherle PeggyChief Scientific OfficerFeb 4, 2025AWARD175,000$1.11$194.3KForm 4
Combs AndrewChief Chemistry OfficerFeb 4, 2025AWARD175,000$1.11$194.3KForm 4
Huang JanePresident, CMOFeb 4, 2025AWARD200,000$1.11$222.0KForm 4
Vaddi Krishnadirector, officer: CEOFeb 4, 2025AWARD496,000$1.11$550.6KForm 4
Huang JanePresident, CMOJan 4, 2025OPTION EX.9,375——Form 4
Huang JanePresident, CMOJan 4, 2025TAX W/H3,859$1.39$5.4KForm 4
Huang JanePresident, CMOJan 4, 2025OPTION EX.9,375——Form 4
Vaddi Krishnadirector, officer: CEODec 31, 2024BUY5,000$1.21$6.0KForm 4
Vaddi Krishnadirector, officer: CEODec 30, 2024BUY10,000$1.20$12.0KForm 4
Combs AndrewChief Chemistry OfficerDec 23, 2024BUY60,000$1.37$82.0KForm 4
Combs AndrewChief Chemistry OfficerDec 20, 2024BUY3,075$1.15$3.5KForm 4
Lim Bryant DavidCLO, Interim CFO, Corp Sec.Dec 19, 2024BUY25,000$0.91$22.6KForm 4
Vaddi Krishnadirector, officer: CEODec 18, 2024BUY100,000$0.93$93.2KForm 4
Vaddi Krishnadirector, officer: CEODec 19, 2024BUY6,888$0.89$6.1KForm 4
Huang JanePresident, CMOJul 4, 2024OPTION EX.9,375——Form 4
Huang JanePresident, CMOJul 4, 2024OPTION EX.9,375——Form 4
Huang JanePresident, CMOJul 4, 2024TAX W/H3,347$3.60$12.0KForm 4
BAKER BROS. ADVISORS LPdirector, 10 percent owner: Jun 14, 2024AWARD23,500$3.90$91.7KForm 4
Sandor VictordirectorJun 14, 2024AWARD23,500$3.90$91.7KForm 4
FRIEDMAN PAUL AdirectorJun 14, 2024AWARD23,500$3.90$91.7KForm 4
Dier MardidirectorJun 14, 2024AWARD23,500$3.90$91.7KForm 4
Bonita David Pdirector, 10 percent owner: Jun 14, 2024AWARD23,500$3.90$91.7KForm 4
Babler MartindirectorJun 14, 2024AWARD23,500$3.90$91.7KForm 4
Lim Bryant DavidCLO, Interim CFO, Corp Sec.May 14, 2024AWARD25,000$3.86$96.5KForm 4
Huang JanePresident, CMOApr 4, 2024OPTION EX.9,375——Form 4
Huang JanePresident, CMOApr 4, 2024OPTION EX.9,375——Form 4
Huang JanePresident, CMOApr 4, 2024TAX W/H3,347$4.74$15.9KForm 4
Lim Bryant DavidChief Legal Officer, Corp Sec.Mar 1, 2024AWARD150,000$4.59$688.5KForm 4
Scherle PeggyChief Scientific OfficerMar 1, 2024AWARD150,000$4.59$688.5KForm 4
Combs AndrewChief Chemistry OfficerMar 1, 2024AWARD150,000$4.59$688.5KForm 4
Chardonnet LaurentChief Financial OfficerMar 1, 2024AWARD150,000$4.59$688.5KForm 4
Huang JanePresident, CMOMar 1, 2024AWARD175,000$4.59$803.3KForm 4
Vaddi Krishnadirector, officer: CEOMar 1, 2024AWARD425,000$4.59$2.0MForm 4
Huang JanePresident, CMOJan 4, 2024OPTION EX.9,375——Form 4
Huang JanePresident, CMOJan 4, 2024OPTION EX.9,375——Form 4
Huang JanePresident, CMOJan 4, 2024TAX W/H3,844$3.77$14.5KForm 4
BAKER BROS. ADVISORS LPdirector, 10 percent owner: Dec 13, 2023AWARD7,343,307$0.00$734.33Form 4
BAKER BROS. ADVISORS LPdirector, 10 percent owner: Dec 13, 2023AWARD593,452$0.00$59.35Form 4
Huang JanePresident, CMOOct 4, 2023OPTION EX.9,375——Form 4
Huang JanePresident, CMOOct 4, 2023OPTION EX.9,375——Form 4
Huang JanePresident, CMOJul 4, 2023OPTION EX.9,375——Form 4
Huang JanePresident, CMOJul 4, 2023OPTION EX.9,375——Form 4
Huang JanePresident, CMOJul 4, 2023TAX W/H3,242$4.65$15.1KForm 4
BAKER BROS. ADVISORS LPdirector, 10 percent owner: Jun 16, 2023AWARD23,500$5.56$130.7KForm 4
Sandor VictordirectorJun 16, 2023AWARD23,500$5.56$130.7KForm 4
FRIEDMAN PAUL AdirectorJun 16, 2023AWARD23,500$5.56$130.7KForm 4
Dier MardidirectorJun 16, 2023AWARD23,500$5.56$130.7KForm 4
Bonita David Pdirector, 10 percent owner: Jun 16, 2023AWARD23,500$5.56$130.7KForm 4
Babler MartindirectorJun 16, 2023AWARD23,500$5.56$130.7KForm 4
Vaddi Krishnadirector, officer: CEOMay 25, 2023BUY900$5.31$4.8KForm 4