Taysha Gene Therapies Inc
TSHAHealthcare|Biotechnology|USA
$6.34
-0.23 (-3.50%)
Tangible Book
$0.74
About
Taysha Gene Therapies Inc is a clinical-stage biotechnology company focused on advancing AAV-based gene therapies for the treatment of severe monogenic diseases of the central nervous system, or CNS. The company's clinical program TSHA-102 is in development for the treatment of Rett syndrome, a rare neurodevelopmental disorder with no approved disease-modifying therapies that address the genetic root cause of the disease. The Company views its operations and manages its business as a single operating segment, the gene therapy segment, which is the business of developing AAV-based gene therapies for the treatment of rare monogenic diseases of the central nervous system.
Stock Price
+148.6%(1Y)
Pipeline Summary
5 total trials2
Phase 1
2
Phase 2
2
Phase 3
0
Phase 4
Withdrawn: 1Active: 3Recruiting: 1
Active Trials (4)
First-in-Human Study of TSHA-101 Gene Therapy for Treatment of Infantile Onset GM2 Gangliosidosis
NCT04798235Infantile GM2 Gangliosidosis (Disorder)
Phase 1Phase 2Active
Enrollment: 3 participants
Safety and Preliminary Efficacy of TSHA-102 Gene Therapy in Pediatric Females Aged >2 to <4 Years With Rett Syndrome
NCT07480564Rett Syndrome
Phase 3Recruiting
Enrollment: 3 participants
Safety and Efficacy of TSHA-102 in Pediatric Females With Rett Syndrome (REVEAL Pediatric Study)
NCT06152237Rett Syndrome
Phase 1Phase 2Active
Enrollment: 6 participants
A Phase 1/2/3 Study of TSHA-102 Gene Therapy in Females With Rett Syndrome (REVEAL Pivotal Study)
NCT05606614Rett Syndrome
Phase 3Active
Enrollment: 17 participants
BioScore
3.5/10
Cautious
Ownership
Recent Insider Trades
Nagendran SukumarSELL
2026-07-10200,000 shares @ $6.24
Nagendran SukumarSELL
2026-04-10200,000 shares @ $4.46
Alam KamranSELL
2026-02-041,655 shares @ $4.52
Nagendran SukumarSELL
2026-01-26116,050 shares @ $4.72
Nolan Sean P.SELL
2026-01-26178,101 shares @ $4.72
Recent News
2026-07-11 00:01:58
2026-07-02 13:36:17
2026-06-30 20:31:35
2026-06-30 13:00:50
2026-06-25 06:56:30
Data last updated: Jul 13, 2026, 12:46 PM