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Upstream Bio, Inc.

UPB
Healthcare|Biotechnology|US
$3.23
+0.02 (+0.62%)
Tangible Book / Share
$4.97
Cash / Share
$4.79

Analyst Consensus

Buy5 analysts
Strong Buy
0
Buy
3
Hold
2
Sell
0
Strong Sell
0
Consensus Target
$25.00
Implied Upside
+674.0%
Low Target
$25.00
High Target
$25.00

Price Target Trend

Last Month
—
0 targets
Last Quarter
$25.00
1 target · +674% vs price
Last Year
$30.33
3 targets · +839% vs price
All Time
$42.60
5 targets · +1219% vs price

Rating Trend

Dec 25
8 buy · 0 hold · 0 sell
Jan 26
8 buy · 0 hold · 0 sell
Feb 26
8 buy · 0 hold · 0 sell
Mar 26
8 buy · 1 hold · 0 sell
Apr 26
7 buy · 1 hold · 0 sell
May 26
7 buy · 1 hold · 0 sell
Jun 26
8 buy · 2 hold · 0 sell
Jul 26
8 buy · 2 hold · 0 sell
Aug 26
7 buy · 2 hold · 0 sell
Sep 26
7 buy · 2 hold · 0 sell
Oct 26
7 buy · 2 hold · 0 sell
Nov 26
6 buy · 2 hold · 0 sell

Recent Price Targets

DateFirmAnalystTargetPrice ThenSource
Aug 11, 2026Truist Financial$25.00(+253%)$7.09TheFly
Mar 27, 2026Evercore ISI$15.00(+73%)$8.67TheFly
Dec 17, 2025Mizuho SecuritiesJoseph Catanzaro$51.00(+80%)$28.33TheFly
Oct 14, 2025Truist Financial$47.00(+134%)$20.08TheFly
Nov 5, 2024Piper SandlerYasmeen Rahimi$75.00(+168%)$28.02StreetInsider

Recent Rating Actions

FirmActionRatingDate
HC Wainwright & Co.maintainBuySep 2, 2026
JP MorganmaintainNeutralAug 14, 2026
Truist SecuritiesmaintainBuyAug 12, 2026
JP MorgandowngradeOverweight →NeutralJun 12, 2026
MizuhomaintainOutperformMay 14, 2026
Evercore ISI GroupdowngradeOutperform →In LineMar 27, 2026

Earnings History

Next report: Mar 17, 2027 · EPS est. $-0.73
Report DateEPS ActualEPS Est.Revenue ActualRevenue Est.
Aug 11, 2026$-0.73$-0.78$773.0K$431.1K
May 13, 2026$-0.75$-0.75$1.0M$1.0M
Mar 26, 2026$-0.79$-0.73$668.0K$584.0K
Nov 5, 2025$-0.63$-0.78$683.0K$521.6K
Aug 6, 2025$-0.74$-0.61$937.0K$317.0K
May 6, 2025$-0.51$-0.49$566.0K$317.0K
Mar 12, 2025$-0.41$-0.56$613.0K$384.8K
Nov 7, 2024$-6.96$-0.54$607.0K$397.3K

News

Analyzing Upstream Bio (NASDAQ:UPB) and Keros Therapeutics (NASDAQ:KROS)

Keros Therapeutics (NASDAQ: KROS - Get Free Report) and Upstream Bio (NASDAQ: UPB - Get Free Report) are both small-cap healthcare companies, but which is the better business? We will compare the two businesses based on the strength of their analyst recommendations, risk, earnings, dividends, institutional ownership, profitability and valuation. Volatility and Risk Keros Therapeutics has a

Oct 5, 2026defenseworld.net
These beaten-down stocks could bounce back in January, if history is any guide

Tax-loss selling is likely to lead these 20 stocks to become artificially depressed in the fourth quarter — and therefore good bets to bounce back in the new year

Sep 21, 2026marketwatch.com
Upstream Bio Presents Results from the Phase 2 VALIANT Trial of Verekitug for the Treatment of Severe Asthma in Oral Presentation at ERS Congress 2026

– Verekitug, 100 mg dosed every 12 weeks, reduced AAER by 56% compared to placebo in patients with severe asthma – – Verekitug also delivered clinically meaningful improvements in lung function (FEV 1 ) and exhaled nitric oxide (FeNO) with every 12-week dosing – – The Company remains on track to initiate Phase 3 trials in severe asthma and CRSwNP in Q1 2027 , designed to deliver best-in-class efficacy in both indications by evaluating a 400 mg quarterly regimen of verekitug in broad patient popu…

Sep 8, 2026globenewswire.com
Upstream Bio Announces Pivotal Phase 3 Development Plans for Verekitug in Both Severe Asthma and CRSwNP

– Following productive FDA discussions, Upstream Bio will study 400 mg of verekitug administered every 12 weeks, versus placebo, in severe asthma and CRSwNP with one pivotal Phase 3 trial in each indication – – The Company's Phase 3 strategy is designed to deliver best-in-class efficacy across both indications by evaluating a high-dose, quarterly regimen of verekitug in broad patient populations – – The Company remains on track to initiate both Phase 3 trials in Q1 2027 – WALTHAM, Mass., Sept. 0…

Sep 1, 2026globenewswire.com
Fannie Mae Announces Sale of Non-Performing Loans

Fannie Mae Announces Sale of Non-Performing Loans PR Newswire WASHINGTON, Aug. 19, 2026

Aug 19, 2026gurufocus.com
Upstream Bio, Inc. (UPB) Reports Q2 Loss, Tops Revenue Estimates

Upstream Bio, Inc. (UPB) came out with a quarterly loss of $0.73 per share versus the Zacks Consensus Estimate of a loss of $0.78. This compares to a loss of $0.74 per share a year ago.

Aug 11, 2026zacks.com