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Upstream Bio, Inc.

UPB
Healthcare|Biotechnology|US
$3.23
+0.02 (+0.62%)
Tangible Book / Share
$4.97
Cash / Share
$4.79
Next Earnings Report
Mar 17, 2027
EPS est. -$0.73 · Revenue est. $524.1K
Financing Filings (last 12 months)
1
Shelf registrations / offering prospectuses — latest Mar 26, 2026 (424B5). Possible dilution.

Upcoming Data Readouts (2)

Sep 2027
Est. completion
P2Severe Asthma
A Long-Term Safety and Efficacy Study of Verekitug (UPB-101) in Adult Participants With Severe Asthma (VALOUR)
NCT06966479n=396
Oct 2027
Est. completion
P2Chronic Obstructive Pulmonary Disease
A Study to Assess the Efficacy and Safety of Verekitug in Participants With COPD
NCT06981078n=666

Recent Press Releases

Upstream Bio Presents Results from the Phase 2 VALIANT Trial of Verekitug for the Treatment of Severe Asthma in Oral Presentation at ERS Congress 2026
Sep 8, 2026 · GlobeNewsWire
Upstream Bio Announces Pivotal Phase 3 Development Plans for Verekitug in Both Severe Asthma and CRSwNP
Sep 1, 2026 · GlobeNewsWire

SEC Filings (44)

Last two years from EDGAR. Insider Form 4s are on the Ownership tab.

FiledFormWhat it isLinks
Nov 6, 2026SC 13G/APassive 5%+ stakeDocumentIndex
Oct 29, 2026SC 13G/APassive 5%+ stakeDocumentIndex
Sep 1, 20268-KMaterial eventDocumentIndex
Aug 12, 2026SC 13G/APassive 5%+ stakeDocumentIndex
Aug 11, 202610-QQuarterly reportDocumentIndex
Aug 11, 20268-KMaterial eventDocumentIndex
Jul 30, 2026SC 13GPassive 5%+ stakeDocumentIndex
Jun 10, 20268-KMaterial eventDocumentIndex
May 15, 2026SC 13G/APassive 5%+ stakeDocumentIndex
May 13, 202610-QQuarterly reportDocumentIndex
May 13, 20268-KMaterial eventDocumentIndex
Apr 16, 2026ARSAnnual report to holdersDocumentIndex
Apr 16, 2026DEFA14AProxy / shareholder voteDocumentIndex
Apr 16, 2026DEF 14AProxy / shareholder voteDocumentIndex
Mar 26, 20268-KMaterial eventDocumentIndex
Mar 26, 2026424B5Offering prospectusDocumentIndex
Mar 26, 2026S-8Employee stock planDocumentIndex
Mar 26, 202610-KAnnual reportDocumentIndex
Mar 26, 20268-KMaterial eventDocumentIndex
Feb 11, 20268-KMaterial eventDocumentIndex
Feb 11, 20268-KMaterial eventDocumentIndex
Nov 14, 2025SC 13G/APassive 5%+ stakeDocumentIndex
Nov 14, 2025SC 13G/APassive 5%+ stakeDocumentIndex
Nov 5, 2025S-3ASRShelf registrationDocumentIndex
Nov 5, 202510-QQuarterly reportDocumentIndex
Nov 5, 20258-KMaterial eventDocumentIndex
Oct 24, 2025SC 13GPassive 5%+ stakeDocumentIndex
Sep 2, 20258-KMaterial eventDocumentIndex
Aug 6, 2025SC 13G/APassive 5%+ stakeDocumentIndex
Aug 6, 202510-QQuarterly reportDocumentIndex
Aug 6, 20258-KMaterial eventDocumentIndex
Jun 12, 20258-KMaterial eventDocumentIndex
May 6, 202510-QQuarterly reportDocumentIndex
May 6, 20258-KMaterial eventDocumentIndex
Apr 17, 2025ARSAnnual report to holdersDocumentIndex
Apr 17, 2025DEFA14AProxy / shareholder voteDocumentIndex
Apr 17, 2025DEF 14AProxy / shareholder voteDocumentIndex
Mar 12, 2025S-8Employee stock planDocumentIndex
Mar 12, 202510-KAnnual reportDocumentIndex
Mar 12, 20258-KMaterial eventDocumentIndex